View source for 9wgm


==Crystal structure of the OcuKAI2d2 protein from Orobanche cumana==
<StructureSection load='9wgm' size='340' side='right'caption='[[9wgm]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9wgm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Orobanche_cernua_var._cumana Orobanche cernua var. cumana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WGM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wgm OCA], [https://pdbe.org/9wgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wgm RCSB], [https://www.ebi.ac.uk/pdbsum/9wgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wgm ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Seed germination of the parasitic plant Orobanche cumana is induced by host-derived strigolactones and dehydrocostus lactone. We show that the KAI2d2 receptor perceives both ligands through distinct modes of interaction. Triazole urea compounds covalently inhibit KAI2d receptors, suppressing germination without affecting sunflower growth.

Orobanche cumana KAI2d2 mediates perception of dehydrocostus lactone and strigolactones and is inhibited by triazole ureas.,Shahul Hameed UF, Jamil M, Zarban R, Saito Y, Alashoor K, Balakrishna A, Asami T, Arold ST, Al-Babili S Plant Commun. 2026 May 7:101889. doi: 10.1016/j.xplc.2026.101889. PMID:42104616<ref>PMID:42104616</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 9wgm" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Orobanche cernua var. cumana]]
[[Category: Arold ST]]
[[Category: Hameed UFS]]