View source for 9wno


==Cryo-EM structure of Candida glabrata GPI mannosyltransferase I bound to Dol-P-Man==
<StructureSection load='9wno' size='340' side='right'caption='[[9wno]], [[Resolution|resolution]] 3.48&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9wno]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WNO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WNO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.48&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MJC:[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]+[(3~{R},14~{E},18~{E},22~{E},30~{Z},34~{E},38~{E})-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-6,10,14,18,22,26,30,34,38,42-decaenyl]+hydrogen+phosphate'>MJC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wno OCA], [https://pdbe.org/9wno PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wno RCSB], [https://www.ebi.ac.uk/pdbsum/9wno PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wno ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GPI14_CANGA GPI14_CANGA] Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Sun H]]
[[Category: Wu WH]]
[[Category: Yan ZF]]