View source for 9ygy


==Structure of a GRP94 folding intermediate engaged with a CCDC134- and FKBP11-bound secretory translocon==
<StructureSection load='9ygy' size='340' side='right'caption='[[9ygy]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9ygy]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YGY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YGY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=ELU:phosphono+[(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl]+hydrogen+phosphate'>ELU</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ygy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ygy OCA], [https://pdbe.org/9ygy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ygy RCSB], [https://www.ebi.ac.uk/pdbsum/9ygy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ygy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SSRA_HUMAN SSRA_HUMAN] TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Jha R]]
[[Category: Keenan RJ]]
[[Category: Yamsek M]]