View source for 9zeb


==Cryo-EM structure of the TREX-2.1 complex (Thp3/Csn12/Sem1) bound to the DEAD-box ATPase Sub2==
<StructureSection load='9zeb' size='340' side='right'caption='[[9zeb]], [[Resolution|resolution]] 3.72&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9zeb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZEB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.72&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AMM:(2~{S})-2-azanyl-3-[4-(phenylmethyl)phenyl]propanoic+acid'>A1AMM</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zeb OCA], [https://pdbe.org/9zeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zeb RCSB], [https://www.ebi.ac.uk/pdbsum/9zeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zeb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THP3_YEAST THP3_YEAST] Forms a complex with CSN12 that is recruited to transcribed genes and required for transcription elongation. May also be involved in pre-mRNA splicing.<ref>PMID:19061648</ref> <ref>PMID:19289793</ref> <ref>PMID:21149575</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Angelos AE]]
[[Category: Clarke BP]]
[[Category: Ren Y]]
[[Category: Xie Y]]