View source for 9zfl


==Structure of an Engineered Sodium/Iodide Symporter (PF-NIS)==
<StructureSection load='9zfl' size='340' side='right'caption='[[9zfl]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9zfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZFL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=REO:PERRHENATE'>REO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zfl OCA], [https://pdbe.org/9zfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zfl RCSB], [https://www.ebi.ac.uk/pdbsum/9zfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zfl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SC5A5_RAT SC5A5_RAT] Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:32084174, PubMed:8559252, PubMed:9341168). Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:9341168).<ref>PMID:32084174</ref> <ref>PMID:8559252</ref> <ref>PMID:9341168</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Abbott GW]]
[[Category: Bianchet MA]]
[[Category: Carrasco N]]
[[Category: Hoffsmith K]]
[[Category: Leyva JA]]
[[Category: Llorente-Esteban A]]
[[Category: Lopez-Gonzalez D]]
[[Category: Manville RW]]
[[Category: Reyna-Neyra A]]
[[Category: Sabbineni H]]