View source for 9zwq


==Crystal structure of the N4BP2 polynucleotide kinase (PNK) domain in complex with ADP and Mg.==
<StructureSection load='9zwq' size='340' side='right'caption='[[9zwq]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9zwq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZWQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZWQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zwq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zwq OCA], [https://pdbe.org/9zwq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zwq RCSB], [https://www.ebi.ac.uk/pdbsum/9zwq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zwq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/N4BP2_HUMAN N4BP2_HUMAN] Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination.<ref>PMID:12730195</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Stanley RE]]
[[Category: Wang H]]