View source for Basic Pancreatic Trypsin Inhibitor

<StructureSection load='3tgi' size='350' side='right' scene='43/430026/Cv/2' caption='Bovine BPTI (in salmon) complex with trypsin (magenta), sulfate and Ca+2 ion (green) (PDB code [[3tgi]])'>

== Function ==

[[Basic Pancreatic Trypsin Inhibitor]] (BPTI) is a small protein which inhibits trypsin and related proteases. <ref>PMID:15299722</ref>  For other trypsin inhibitors see [[Trypsin inhibitor]].

== Relevance ==

BPTI is used as drug called Aprotinin used to reduce bleeding during surgery.

== Structural highlights ==

<scene name='43/430026/Cv/3'>Residue K15 of BPTI</scene> extends into the active site of trypsin and inhibits its proteolytic function. <ref>PMID:10210204</ref>

== 3D Structures of BPTI ==
[[BPTI 3D structures]]

</StructureSection>

== References ==
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