View source for C-di-GMP

<applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP, as found in complex with the diguanylate cyclase PleD  [[2v0n]]' />

Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)<br><br>



C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.

<scene name='C-di-GMP/C-di-gmp/3'>C-di-GMP</scene>
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties.  It tends to associate to form  <scene name='C-di-GMP/C-di-gmp/4'>dimers</scene> with intercalated, stacked bases.


Several protein structures involved in c-di-GMP signaling have been determined (see  [[C-di-GMP signaling]]).

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[http://www.uniprot.org/keywords/973 UNIPROT link]
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==References==
Reviews:
<ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref>
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[[Category: C-di-GMP]]