View source for HIV Protease Resistance

{| class="wikitable" border="1" width="98%" style="text-align:center"
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!  colspan="40" align="center"| Resistance Mutations
|-
!
!Inhibitor/ Mutation Site
!L10
!V11
!I13
!G16
!K20
!L24
!D30
!V32
!L33
!E34
!E35
!M36
!K43
!M46
!I47
!G48
!I50
!F53
!I54
!Q58
!D60
!I62
!L63
!I64
!H69
!A71
!G73
!T74
!L76
!V77
!V82
!N83
!I84
!I85
!N88
!L89
!L90
!I93
|-
!<scene name='HIV_Protease_Resistance/Ritonavir/3'>Visualize</scene>
![[Ritonavir]]
!I,R,V
!-
!-
!-
!M,R
!-
!-
!I
!F
!-
!-
!I
!-
!I,L
!-
!-
!-
!-
!<font color='red'>V,L</font>
!-
!-
!-
!-
!-
!-
!V,T
!-
!-
!-
!<font color='red'>I</font>
!<font color='red'>A,F,T, S</font>
!-
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Indinavir/4'>Visualize</scene>
![[Indinavir]]
!I,R,V
!-
!-
!-
!M,R
!I
!-
!I
!-
!-
!-
!I
!-
!<font color='red'>I,L</font>
!-
!-
!-
!-
!V
!-
!-
!-
!-
!-
!-
!V,T
!<font color='red'>S,A</font>
!-
!-
!<font color='red'>I</font>
!<font color='red'>A,F,T</font>
!
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Saquinavir/2'>Visualize</scene>
![[Saquinavir]]
!I,R,V
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!<font color='red'>V</font>
!-
!-
!V,L
!-
!-
!-
!-
!-
!-
!V,T
!<font color='red'>S</font>
!-
!-
!<font color='red'>I</font>
!A
!-
!V
!-
!-
!-
!<font color='red'>M</font>
!-
|-
!<scene name='HIV_Protease_Resistance/Nelfinavir/1'>Visualize</scene>
![[Nelfinavir]]
!F,I
!-
!-
!-
!-
!-
!<font color='red'>N</font>
!-
!-
!-
!-
!I
!-
!I,L
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!-
!V,T
!-
!-
!-
!I
!A,F,T, S
!-
!V
!-
!D,S
!
!<font color='red'>M</font>
!-
|-
!<scene name='HIV_Protease_Resistance/Amprenavir/1'>Visualize</scene>
![[Amprenavir]]
!F,I,R, V
!-
!-
!-
!-
!-
!-
!I
!-
!-
!-
!-
!-
!I,L
!V
!-
!<font color='red'>V</font>
!-
!L,V,M
!-
!-
!-
!-
!-
!-
!-
!S
!-
!-
!-
!-
!-
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Atazanavir/1'>Visualize</scene>
![[Atazanavir]]
!I,F,V
!-
!-
!-
!R,M,I
!I
!-
!I
!I,F,V
!-
!-
!I,L,V
!-
!I
!-
!V
!<font color='red'>L</font>
!-
!L
!-
!-
!-
!-
!-
!-
!V
!C,S,T, A
!-
!-
!-
!A
!-
!V
!-
!S
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Lopinavir_and_ritonavir/1'>Visualize</scene>
![[Lopinavir]] & [[Ritonavir]]
!F,I,R, V
!-
!-
!-
!M,R
!I
!-
!<font color='red'>I</font>
!F
!-
!-
!-
!-
!I,L
!<font color='red'>V,A</font>
!-
!V
!L
!V,L,A, M,T,S
!-
!-
!-
!P
!-
!-
!V,T
!S
!-
!<font color='red'>V</font>
!-
!<font color='red'>A,F,T, S</font>
!-
!V
!-
!-
!-
!M
!
|-
!<scene name='HIV_Protease_Resistance/Atazanavir_and_ritonavir/1'>Visualize</scene>
![[Atazanavir]] & [[Ritonavir]]
!I,F,V, C
!-
!-
!E
!R,M,I, T,V
!I
!-
!I
!I,F,V
!Q
!-
!I,L,V
!-
!I,L
!-
!V
!<font color='red'>V</font>
!L,Y
!L,V,M, T,A
!-
!E
!V
!-
!L,M,V
!-
!V,I,T, L
!C,S,T, A
!-
!-
!-
!A,T,F, I
!-
!<font color='red'>V</font>
!V
!<font color='red'>S</font>
!-
!M
!L,M
|-
!<scene name='HIV_Protease_Resistance/Darunavir_and_ritonavir/1'>Visualize</scene>
![[Darunavir]] & [[Ritonavir]]
!-
!I
!-
!-
!-
!-
!-
!I
!F
!-
!-
!-
!-
!-
!<font color='red'>V</font>
!-
!<font color='red'>V</font>
!-
!<font color='red'>M,L</font>
!-
!-
!-
!-
!-
!-
!-
!-
!P
!<font color='red'>V</font>
!-
!-
!-
!<font color='red'>V</font>
!-
!-
!V
!-
!-
|-
!<scene name='HIV_Protease_Resistance/Fosamprenavir_and_ritonavir/1'>Visualize</scene>
![[Fosamprenavir]] & [[Ritonavir]]
!F,I,R, V
!-
!-
!-
!-
!-
!-
!I
!-
!-
!-
!-
!-
!I,L
!V
!-
!<font color='red'>V</font>
!-
!L,V,M
!-
!-
!-
!-
!-
!-
!-
!S
!-
!V
!-
!A,F,S, T
!-
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Indinavir_and_ritonair/1'>Visualize</scene>
![[Indinavir]] & [[Ritonavir]]
!I,R,V
!-
!-
!-
!M,R
!I
!-
!I
!-
!-
!-
!I
!-
!<font color='red'>I,L</font>
!-
!-
!-
!-
!V
!-
!-
!-
!-
!-
!-
!V,T
!S,A
!-
!V
!I
!<font color='red'>A,F,T</font>
!-
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
!<scene name='HIV_Protease_Resistance/Saquinavir_and_ritonavir/1'>Visualize</scene>
![[Saquinavir]] & [[Ritonavir]]
!I,R,V
!-
!-
!-
!-
!I
!-
!-
!-
!-
!-
!-
!-
!-
!-
!<font color='red'>V</font>
!-
!-
!V,L
!-
!-
!V
!-
!-
!-
!V,T
!S
!-
!-
!I
!A,F,T, S
!-
!V
!-
!-
!-
!<font color='red'>M</font>
!-
|-
!<scene name='HIV_Protease_Resistance/Tip_and_rot/1'>Visualize</scene>
![[Tipranavir]] & [[Ritonavir]]
!V
!-
!V
!-
!M,R
!-
!-
!-
!F
!-
!G
!I
!T
!L
!<font color='red'>V</font>
!-
!-
!-
!A,M,V
!<font color='red'>E<font>
!-
!-
!-
!-
!K
!-
!-
!<font color='red'>P</font>
!-
!-
!<font color='red'>L,T</font>
!D
!<font color='red'>V</font>
!-
!-
!-
!M
!-
|-
|}