View source for Hemolysin

<StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''>
== Function ==
'''Hemolysin''' (HL) is exotoxin from bacteria which causes lysis of red blood cells<ref>PMID:20110774</ref>. 
*'''alpha-hemolysin''' is a transmembrane pore-forming heptameric molecule<ref>PMID:8943190</ref>.  See details for in [[Pore forming toxin, α-hemolysin]].  
*'''delta-hemolysin''' is a 26 amino acid peptide from the bacterium ''Staphylococcus'' exhibiting antimicrobial activity against'' Legionerlla'' <ref>PMID:19150639</ref>. 

See details of hemolysin E in [[Molecular Playground/ClyA]].

For toxins in Proteopdia see [[Toxins]].

== Relevance ==
HL acts as a virulence factor in the pathogenesis of invasive infections<ref>PMID:12564994</ref>.

==3D Printed Physical Model of Hemolysin==

Shown below is a 3D printed physical model of Hemolysin. The model is shown in alpha carbon backbone format with each chain colored uniquely. 

[[Image:hemolysin1_centerForBioMolecularModeling.jpg|550px]]
[[Image:hemolysin2_centerForBioMolecularModeling.jpg|550px]]

====The MSOE Center for BioMolecular Modeling====

[[Image:CbmUniversityLogo.jpg | left | 150px]]

The [http://cbm.msoe.edu MSOE Center for BioMolecular Modeling] uses 3D printing technology to create physical models of protein and molecular structures, making the invisible molecular world more tangible and comprehensible. To view more protein structure models, visit our [http://cbm.msoe.edu/educationalmedia/modelgallery/ Model Gallery].

== 3D Structures of hemolysin ==

[[Hemolysin 3D structures]]

</StructureSection>

== References ==
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[[Category:Topic Page]]
[[Category:3D printer files]]