View source for VCA0042 complexed with c-di-GMP

<StructureSection load="2rde" size="350" color="" frame="true"  spin="on" Scene='2rde/Plzd_start/1'  side="right" caption='PlZD_VIBCH (PilZ domain) homology model [[2rde]]' >

[[Image:2rde.png|left|200px]]

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===Crystal structure of VCA0042 complexed with c-di-GMP ([[2rde]])===

==Pilz domain==

<scene name='2rde/Plzd_start/1'>PilZ</scene>

<scene name='2rde/Plzd_active/1'>Binding sites</scene> (R136, R140, D162, S164, G167)

<scene name='2rde/Plzd_active_ligand/2'>Binding sites + ligand</scene>

<scene name='2rde/Pilz_domain/1'>Active sites</scene> (R136, R140, D162, S164, G167)

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{{ABSTRACT_PUBMED_18034161}}

==About this Structure==
2RDE is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o395 Vibrio cholerae o395]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDE OCA]. 
</StructureSection>
==Reference==
The structural basis of cyclic diguanylate signal transduction by PilZ domains., Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF, EMBO J. 2007 Dec 12;26(24):5153-66. Epub 2007 Nov 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18034161 18034161]
[[Category: Vibrio cholerae o395]]
[[Category: Benach, J.]]
[[Category: Camilli, A.]]
[[Category: Forouhar, F.]]
[[Category: Handelman, S.]]
[[Category: Hunt, J F.]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Neely, H.]]
[[Category: Seetharaman, J.]]
[[Category: Swaminathan, S S.]]
[[Category: Tamayo, R.]]
[[Category: C-di-GMP]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Vca0042]]
[[Category: Vibrio cholerae]]

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Created by [[User:Tilman Schirmer|Tilman Schirmer]].