1cms - Revision history

OCA at 06:29, 30 October 2024

2024-10-30T06:29:49Z

← Older revision		Revision as of 06:29, 30 October 2024
Line 14:		Line 14:
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/1cms_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/1cms_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 05:26, 5 June 2024

2024-06-05T05:26:38Z

@@ Line 19: / Line 19: @@
 </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cms ConSurf].
 <div style="clear:both"></div>
 __TOC__
 </StructureSection>

OCA at 15:40, 13 March 2024

2024-03-13T15:40:53Z

← Older revision		Revision as of 15:40, 13 March 2024
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	<StructureSection load='1cms' size='340' side='right'caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1cms' size='340' side='right'caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Chymosin Chymosin~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4~~.~~23.4~~ 3~~.4.23.4] </span>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [https://pdbe.org/1cms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [https://www.ebi.ac.uk/pdbsum/1cms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cms ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [https://pdbe.org/1cms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [https://www.ebi.ac.uk/pdbsum/1cms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cms ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN]] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.		[https://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cms ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cms ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The crystal structure of recombinant bovine chymosin (EC 3.4.23.4; renin), which was cloned and expressed in Escherichia coli, has been determined using X-ray data extending to 2.3 A resolution. The crystals of the enzyme used in this study belong to the space group I222 with unit cell dimensions alpha = 72.7 A, b = 80.3 A, and c = 114.8 A. The structure was solved by the molecular replacement method and was refined by a restrained least-squares procedure. The crystallographic R factor is 0.165 and the deviation of bond distances from ideality is 0.020 A. The resulting model includes all 323 amino acid residues, as well as 297 water molecules. The enzyme has an irregular shape with approximate maximum dimensions of 40 x 50 x 65 A. The secondary structure consists primarily of parallel and antiparallel beta-strands with a few short alpha-helices. The enzyme can be subdivided into N- and C-terminal domains which are separated by a deep cleft containing the active aspartate residues Asp-34 and Asp-216. The amino acid residues and waters at the active site form an extensive hydrogen-bonded network which maintains the pseudo 2-fold symmetry of the entire structure. A comparison of recombinant chymosin with other acid proteinases reveals the high degree of structural similarity with other members of this family of proteins as well as the subtle differences which make chymosin unique. In particular, Tyr-77 of the flap region of chymosin does not hydrogen bond to Trp-42 but protrudes out in the P1 pocket forming hydrophobic interactions with Phe-119 and Leu-32. This may have important implications concerning the mechanism of substrate binding and substrate specificity.

	~~The three-dimensional structure of recombinant bovine chymosin at 2.3 A resolution.,Gilliland GL, Winborne EL, Nachman J, Wlodawer A Proteins. 1990;8(1):82-101. PMID:2217166<ref>PMID:2217166</ref>~~

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 1cms" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bovin]]~~		[[Category: Bos taurus]]
	~~[[Category: Chymosin~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Gilliland~~, G L~~]]		[[Category: Gilliland GL]]
	[[Category: Nachman, J]]		[[Category: Nachman J]]
	[[Category: Winborne~~, E L~~]]		[[Category: Winborne EL]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer A]]

OCA at 10:38, 14 July 2021

2021-07-14T10:38:11Z

← Older revision		Revision as of 10:38, 14 July 2021
Line 3:		Line 3:
	<StructureSection load='1cms' size='340' side='right'caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1cms' size='340' side='right'caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [~~http~~://pdbe.org/1cms PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1cms PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1cms ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [https://pdbe.org/1cms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [https://www.ebi.ac.uk/pdbsum/1cms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cms ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN]] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.		[[https://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN]] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:46, 10 October 2019

2019-10-10T06:46:47Z

← Older revision		Revision as of 06:46, 10 October 2019
Line 1:		Line 1:

	==THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION==		==THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION==
	<StructureSection load='1cms' size='340' side='right' caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1cms' size='340' side='right'caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/1cms_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/1cms_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 34:		Line 34:
	[[Category: Bovin]]		[[Category: Bovin]]
	[[Category: Chymosin]]		[[Category: Chymosin]]
			[[Category: Large Structures]]
	[[Category: Gilliland, G L]]		[[Category: Gilliland, G L]]
	[[Category: Nachman, J]]		[[Category: Nachman, J]]
	[[Category: Winborne, E L]]		[[Category: Winborne, E L]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer, A]]

OCA at 08:09, 29 November 2017

2017-11-29T08:09:50Z

← Older revision		Revision as of 08:09, 29 November 2017
Line 1:		Line 1:

	==THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION==		==THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION==
	<StructureSection load='1cms' size='340' side='right' caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1cms' size='340' side='right' caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://pdbe.org/1cms PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://pdbe.org/1cms PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1cms ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:05, 8 February 2016

2016-02-08T23:05:07Z

← Older revision		Revision as of 23:05, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cms ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:13, 10 September 2015

2015-09-10T16:13:32Z

← Older revision		Revision as of 16:13, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1cms' size='340' side='right' caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1cms' size='340' side='right' caption='[[1cms]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://pdbe.org/1cms PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 1cms" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bos taurus~~]]		[[Category: Bovin]]
	[[Category: Chymosin]]		[[Category: Chymosin]]
	[[Category: Gilliland, G L]]		[[Category: Gilliland, G L]]

OCA at 02:45, 25 December 2014

2014-12-25T02:45:17Z

← Older revision		Revision as of 02:45, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN]] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 18:23, 22 December 2014

2014-12-22T18:23:18Z

← Older revision		Revision as of 18:23, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1cms]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CMS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1CMS FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cms OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cms RCSB], [http://www.ebi.ac.uk/pdbsum/1cms PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Chymosin]]		[[Category: Chymosin]]
	[[Category: Gilliland, G L.]]		[[Category: Gilliland, G L]]
	[[Category: Nachman, J.]]		[[Category: Nachman, J]]
	[[Category: Winborne, E L.]]		[[Category: Winborne, E L]]
	[[Category: Wlodawer, A.]]		[[Category: Wlodawer, A]]