1gnu - Revision history

OCA at 12:01, 13 December 2023

2023-12-13T12:01:23Z

← Older revision		Revision as of 12:01, 13 December 2023
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	<StructureSection load='1gnu' size='340' side='right'caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1gnu' size='340' side='right'caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [https://pdbe.org/1gnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [https://www.ebi.ac.uk/pdbsum/1gnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [https://pdbe.org/1gnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [https://www.ebi.ac.uk/pdbsum/1gnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN]] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref>		[https://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Driscoll~~, P C~~]]		[[Category: Driscoll PC]]
	[[Category: Harris, R]]		[[Category: Harris R]]
	[[Category: Keep~~, N H~~]]		[[Category: Keep NH]]
	[[Category: Knight, D]]		[[Category: Knight D]]
	[[Category: Moss, S]]		[[Category: Moss S]]
	~~[[Category: Receptor]]~~
	~~[[Category: Transport]]~~
	~~[[Category: Ubiquitin-like~~]]

OCA at 11:26, 28 July 2021

2021-07-28T11:26:21Z

← Older revision		Revision as of 11:26, 28 July 2021
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	<StructureSection load='1gnu' size='340' side='right'caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1gnu' size='340' side='right'caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [~~http~~://pdbe.org/1gnu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gnu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [https://pdbe.org/1gnu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [https://www.ebi.ac.uk/pdbsum/1gnu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN]] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref>		[[https://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN]] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:42, 23 October 2019

2019-10-23T08:42:17Z

← Older revision		Revision as of 08:42, 23 October 2019
Line 1:		Line 1:

	==GABA(A) receptor associated protein GABARAP==		==GABA(A) receptor associated protein GABARAP==
	<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1gnu' size='340' side='right'caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
Line 30:		Line 30:

	==See Also==		==See Also==
	*[[GABA~~(A)~~ receptor-associated protein\|GABA~~(A)~~ receptor-associated protein]]		*[[GABA receptor-associated protein 3D structures\|GABA receptor-associated protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Driscoll, P C]]		[[Category: Driscoll, P C]]
	[[Category: Harris, R]]		[[Category: Harris, R]]

OCA at 06:26, 3 January 2018

2018-01-03T06:26:39Z

← Older revision		Revision as of 06:26, 3 January 2018
Line 1:		Line 1:
	==GABA(A) ~~RECEPTOR ASSOCIATED PROTEIN~~ GABARAP==
			==GABA(A) receptor associated protein GABARAP==
	<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://pdbe.org/1gnu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://pdbe.org/1gnu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gnu_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gnu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1gnu" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1gnu" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[GABA(A) receptor-associated protein\|GABA(A) receptor-associated protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:33, 10 February 2016

2016-02-10T04:33:24Z

← Older revision		Revision as of 04:33, 10 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gnu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:25, 11 September 2015

2015-09-11T05:25:16Z

← Older revision		Revision as of 05:25, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://pdbe.org/1gnu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 1gnu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Driscoll, P C]]		[[Category: Driscoll, P C]]
	[[Category: Harris, R]]		[[Category: Harris, R]]

OCA at 11:49, 25 December 2014

2014-12-25T11:49:22Z

← Older revision		Revision as of 11:49, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/GBRAP_HUMAN GBRAP_HUMAN]] May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity).<ref>PMID:15977068</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:25, 22 December 2014

2014-12-22T19:25:55Z

← Older revision		Revision as of 19:25, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Driscoll, P C.]]		[[Category: Driscoll, P C]]
	[[Category: Harris, R.]]		[[Category: Harris, R]]
	[[Category: Keep, N H.]]		[[Category: Keep, N H]]
	[[Category: Knight, D.]]		[[Category: Knight, D]]
	[[Category: Moss, S.]]		[[Category: Moss, S]]
	[[Category: Receptor]]		[[Category: Receptor]]
	[[Category: Transport]]		[[Category: Transport]]
	[[Category: Ubiquitin-like]]		[[Category: Ubiquitin-like]]

OCA at 09:20, 28 September 2014

2014-09-28T09:20:43Z

← Older revision		Revision as of 09:20, 28 September 2014
Line 1:		Line 1:
	[[Image:~~1gnu~~.~~png~~\|~~left~~\|~~200px~~]]		==GABA(A) RECEPTOR ASSOCIATED PROTEIN GABARAP==
			<StructureSection load='1gnu' size='340' side='right' caption='[[1gnu]], [[Resolution\|resolution]] 1.75Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[1gnu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GNU FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene><br>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gnu RCSB], [http://www.ebi.ac.uk/pdbsum/1gnu PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gnu_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The gamma-aminobutyric acid receptor type A (GABA(A)) receptor-associated protein (GABARAP) has been reported to mediate the interaction between the GABA(A) receptor and microtubules. We present the three-dimensional structure of GABARAP obtained by x-ray diffraction at 1.75 A resolution. The structure was determined by molecular replacement using the structure of the homologous protein GATE-16. NMR spectroscopy of isotope-labeled GABARAP showed the structure in solution to be compatible with the overall fold but showed evidence of conformation heterogeneity that is not apparent in the crystal structure. We assessed the binding of GABARAP to peptides derived from reported binding partner proteins, including the M3-M4 loop of the gamma2 subunit of the GABA(A) receptor and the acidic carboxyl-terminal tails of human alpha- and beta-tubulin. There is a small area of concentrated positive charge on one surface of GABARAP, which we found interacts weakly with all peptides tested, but we found no evidence for specific binding to the proposed physiological target peptides. These results are compatible with a more general role in membrane targeting and transportation for the GABARAP family of proteins.

	~~{{STRUCTURE_1gnu\| PDB=1gnu \| SCENE= }}~~		The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein.,Knight D, Harris R, McAlister MS, Phelan JP, Geddes S, Moss SJ, Driscoll PC, Keep NH J Biol Chem. 2002 Feb 15;277(7):5556-61. Epub 2001 Nov 29. PMID:11729197<ref>PMID:11729197</ref>

	~~===GABA(A) RECEPTOR ASSOCIATED PROTEIN GABARAP===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_11729197}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[1gnu]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1GNU OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:011729197<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Driscoll, P C.]]		[[Category: Driscoll, P C.]]

OCA: Protected "1gnu" [edit=sysop:move=sysop]

2012-11-21T15:47:08Z

Protected "1gnu" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:47, 21 November 2012
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