1iw4 - Revision history

OCA at 07:18, 9 October 2024

2024-10-09T07:18:46Z

← Older revision		Revision as of 07:18, 9 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [https://pdbe.org/1iw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [https://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [https://pdbe.org/1iw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [https://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:23, 14 June 2023

2023-06-14T08:23:18Z

← Older revision		Revision as of 08:23, 14 June 2023
Line 1:		Line 1:

	==Solution structure of ascidian trypsin inhibitor==		==Solution structure of ascidian trypsin inhibitor==
	<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
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	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ITRP_HALRO ITRP_HALRO]] Potent inhibitor of trypsin.		[https://www.uniprot.org/uniprot/ITRP_HALRO ITRP_HALRO] Potent inhibitor of trypsin.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Halocynthia roretzi]]		[[Category: Halocynthia roretzi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hasegawa, J]]		[[Category: Hasegawa J]]
	[[Category: Hemmi, H]]		[[Category: Hemmi H]]
	[[Category: Kobayashi, Y]]		[[Category: Kobayashi Y]]
	[[Category: Kumazaki, T]]		[[Category: Kumazaki T]]
	[[Category: Kyogoku, Y]]		[[Category: Kyogoku Y]]
	[[Category: Nemoto, N]]		[[Category: Nemoto N]]
	[[Category: Nishioka, F]]		[[Category: Nishioka F]]
	[[Category: Yokosawa, H]]		[[Category: Yokosawa H]]
	[[Category: Yoshida, T]]		[[Category: Yoshida T]]
	~~[[Category: Ascidian]]~~
	~~[[Category: Cystine-stabilized alpha-helical motif]]~~
	~~[[Category: Disulfide bond]]~~
	~~[[Category: Kazal-type inhibitor]]~~
	~~[[Category: Protein binding]]~~
	~~[[Category: Solution structure]]~~
	~~[[Category: Trypsin inhibitor~~]]

OCA at 06:42, 1 December 2021

2021-12-01T06:42:28Z

← Older revision		Revision as of 06:42, 1 December 2021
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	<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [~~http~~://pdbe.org/1iw4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [https://pdbe.org/1iw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [https://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ITRP_HALRO ITRP_HALRO]] Potent inhibitor of trypsin.		[[https://www.uniprot.org/uniprot/ITRP_HALRO ITRP_HALRO]] Potent inhibitor of trypsin.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
	*[[NMR Ensembles of Models\|NMR Ensembles of Models]]		*[[Trypsin inhibitor 3D structures\|Trypsin inhibitor 3D structures]]
	*[[Trypsin inhibitor\|Trypsin inhibitor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:30, 26 February 2020

2020-02-26T09:30:51Z

← Older revision		Revision as of 09:30, 26 February 2020
Line 3:		Line 3:
	<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cynthia_roretzi Cynthia~~ roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://pdbe.org/1iw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://pdbe.org/1iw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>
	</table>		</table>
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Cynthia~~ roretzi]]		[[Category: Halocynthia roretzi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hasegawa, J]]		[[Category: Hasegawa, J]]

OCA at 06:59, 10 July 2019

2019-07-10T06:59:32Z

← Older revision		Revision as of 06:59, 10 July 2019
Line 1:		Line 1:

	==Solution structure of ascidian trypsin inhibitor==		==Solution structure of ascidian trypsin inhibitor==
	<StructureSection load='1iw4' size='340' side='right' caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1iw4' size='340' side='right'caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cynthia_roretzi Cynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cynthia_roretzi Cynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Cynthia roretzi]]		[[Category: Cynthia roretzi]]
			[[Category: Large Structures]]
	[[Category: Hasegawa, J]]		[[Category: Hasegawa, J]]
	[[Category: Hemmi, H]]		[[Category: Hemmi, H]]

OCA at 09:50, 4 October 2017

2017-10-04T09:50:30Z

← Older revision		Revision as of 09:50, 4 October 2017
Line 1:		Line 1:

	==Solution structure of ascidian trypsin inhibitor==		==Solution structure of ascidian trypsin inhibitor==
	<StructureSection load='1iw4' size='340' side='right' caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1iw4' size='340' side='right' caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Halocynthia_roretzi Halocynthia~~ roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cynthia_roretzi Cynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://pdbe.org/1iw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://pdbe.org/1iw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1iw4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Halocynthia~~ roretzi]]		[[Category: Cynthia roretzi]]
	[[Category: Hasegawa, J]]		[[Category: Hasegawa, J]]
	[[Category: Hemmi, H]]		[[Category: Hemmi, H]]

OCA at 20:49, 10 September 2015

2015-09-10T20:49:11Z

← Older revision		Revision as of 20:49, 10 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://pdbe.org/1iw4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 1iw4" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[NMR Ensembles of Models\|NMR Ensembles of Models]]		*[[NMR Ensembles of Models\|NMR Ensembles of Models]]
			*[[Trypsin inhibitor\|Trypsin inhibitor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:58, 25 December 2014

2014-12-25T05:58:23Z

← Older revision		Revision as of 05:58, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/ITRP_HALRO ITRP_HALRO]] Potent inhibitor of trypsin.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 14:02, 17 December 2014

2014-12-17T14:02:45Z

← Older revision		Revision as of 14:02, 17 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_1iw4~~\| ~~PDB~~=1iw4 ~~\| SCENE~~= }}		==Solution structure of ascidian trypsin inhibitor==
	===~~Solution~~ structure of ascidian trypsin inhibitor~~===~~		<StructureSection load='1iw4' size='340' side='right' caption='[[1iw4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	~~{{ABSTRACT_PUBMED_12186551}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[1iw4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halocynthia_roretzi Halocynthia roretzi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IW4 FirstGlance]. <br>
			</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1iw4 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The three-dimensional solution structure of ascidian trypsin inhibitor (ATI), a 55 amino acid residue protein with four disulfide bridges, was determined by means of two-dimensional nuclear magnetic resonance (2D NMR) spectroscopy. The resulting structure of ATI was characterized by an alpha-helical conformation in residues 35-42 and a three-stranded antiparallel beta-sheet in residues 22-26, 29-32, and 48-50. The presence of an alpha-helical conformation was predicted from the consensus sequences of the cystine-stabilized alpha-helical (CSH) motif, which is characterized by an alpha-helix structure in the Cys-X(1)-X(2)-X(3)-Cys portion (corresponding to residues 37-41), linking to the Cys-X-Cys portion (corresponding to residues 12-14) folded in an extended structure. The secondary structure and the overall folding of the main chain of ATI were very similar to those of the Kazal-type inhibitors, such as Japanese quail ovomucoid third domain (OMJPQ3) and leech-derived tryptase inhibitor form C (LDTI-C), although ATI does not show extensive sequence homology to these inhibitors except for a few amino acid residues and six of eight half-cystines. On the basis of these findings, we realign the amino acid sequences of representative Kazal-type inhibitors including ATI and discuss the unique structure of ATI with four disulfide bridges.

	~~==About this Structure==~~		Solution structure of ascidian trypsin inhibitor determined by nuclear magnetic resonance spectroscopy.,Hemmi H, Yoshida T, Kumazaki T, Nemoto N, Hasegawa J, Nishioka F, Kyogoku Y, Yokosawa H, Kobayashi Y Biochemistry. 2002 Aug 27;41(34):10657-64. PMID:12186551<ref>PMID:12186551</ref>
	~~[[1iw4]] is a 1 chain~~ structure ~~with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Halocynthia_roretzi Halocynthia roretzi]~~. ~~Full experimental information is available from [http~~://~~oca~~.~~weizmann~~.ac.~~il/oca-bin~~/~~ocashort?id=1IW4 OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[NMR Ensembles of Models\|NMR Ensembles of Models]]		*[[NMR Ensembles of Models\|NMR Ensembles of Models]]
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Halocynthia roretzi]]		[[Category: Halocynthia roretzi]]
	[[Category: Hasegawa, J.]]		[[Category: Hasegawa, J]]
	[[Category: Hemmi, H.]]		[[Category: Hemmi, H]]
	[[Category: Kobayashi, Y.]]		[[Category: Kobayashi, Y]]
	[[Category: Kumazaki, T.]]		[[Category: Kumazaki, T]]
	[[Category: Kyogoku, Y.]]		[[Category: Kyogoku, Y]]
	[[Category: Nemoto, N.]]		[[Category: Nemoto, N]]
	[[Category: Nishioka, F.]]		[[Category: Nishioka, F]]
	[[Category: Yokosawa, H.]]		[[Category: Yokosawa, H]]
	[[Category: Yoshida, T.]]		[[Category: Yoshida, T]]
	[[Category: Ascidian]]		[[Category: Ascidian]]
	[[Category: Cystine-stabilized alpha-helical motif]]		[[Category: Cystine-stabilized alpha-helical motif]]

OCA at 10:20, 11 March 2013

2013-03-11T10:20:05Z

← Older revision		Revision as of 10:20, 11 March 2013
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	~~[[Image:1iw4.png\|left\|200px]]~~

	{{STRUCTURE_1iw4\| PDB=1iw4 \| SCENE= }}		{{STRUCTURE_1iw4\| PDB=1iw4 \| SCENE= }}

	===Solution structure of ascidian trypsin inhibitor===		===Solution structure of ascidian trypsin inhibitor===

	{{ABSTRACT_PUBMED_12186551}}		{{ABSTRACT_PUBMED_12186551}}