1o7j - Revision history

OCA at 12:29, 13 December 2023

2023-12-13T12:29:30Z

← Older revision		Revision as of 12:29, 13 December 2023
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	<StructureSection load='1o7j' size='340' side='right'caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1o7j' size='340' side='right'caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Erwinia_chrysanthemi Erwinia~~ chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Dickeya_chrysanthemi Dickeya chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=EDO:1,2~~-~~ETHANEDIOL'>EDO</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]~~</~~div~~><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [https://pdbe.org/1o7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [https://www.ebi.ac.uk/pdbsum/1o7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [https://pdbe.org/1o7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [https://www.ebi.ac.uk/pdbsum/1o7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7j ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/ASPG_DICCH ASPG_DICCH]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Asparaginase]]~~		[[Category: Dickeya chrysanthemi]]
	~~[[Category: Erwinia~~ chrysanthemi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Aghaiypour, K]]		[[Category: Aghaiypour K]]
	[[Category: Dauter, M]]		[[Category: Dauter M]]
	[[Category: Dauter, Z]]		[[Category: Dauter Z]]
	[[Category: Lubkowski, J]]		[[Category: Lubkowski J]]
	[[Category: Wlodawer, A]]		[[Category: Wlodawer A]]
	~~[[Category: Atomic resolution]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: L-asparaginase~~]]

OCA at 07:06, 24 February 2021

2021-02-24T07:06:40Z

← Older revision		Revision as of 07:06, 24 February 2021
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	<StructureSection load='1o7j' size='340' side='right'caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1o7j' size='340' side='right'caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [~~http~~://pdbe.org/1o7j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1o7j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7j ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [https://pdbe.org/1o7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [https://www.ebi.ac.uk/pdbsum/1o7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:04, 23 May 2019

2019-05-23T07:04:36Z

← Older revision		Revision as of 07:04, 23 May 2019
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	==Atomic resolution structure of Erwinia chrysanthemi L-asparaginase==		==Atomic resolution structure of Erwinia chrysanthemi L-asparaginase==
	<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1o7j' size='340' side='right'caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 1o7j" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1o7j" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Asparaginase 3D structures\|Asparaginase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: Erwinia chrysanthemi]]		[[Category: Erwinia chrysanthemi]]
			[[Category: Large Structures]]
	[[Category: Aghaiypour, K]]		[[Category: Aghaiypour, K]]
	[[Category: Dauter, M]]		[[Category: Dauter, M]]

OCA at 07:28, 7 February 2018

2018-02-07T07:28:44Z

← Older revision		Revision as of 07:28, 7 February 2018
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	==~~ATOMIC RESOLUTION STRUCTURE OF ERWINIA CHRYSANTHEMI~~ L-~~ASPARAGINASE~~==
			==Atomic resolution structure of Erwinia chrysanthemi L-asparaginase==
	<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Dickeya_chrysanthemi Dickeya~~ chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://pdbe.org/1o7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://pdbe.org/1o7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1o7j ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7j_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7j_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</div>		</div>
	<div class="pdbe-citations 1o7j" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1o7j" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Asparaginase\|Asparaginase]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: ~~Dickeya~~ chrysanthemi]]		[[Category: Erwinia chrysanthemi]]
	[[Category: Aghaiypour, K]]		[[Category: Aghaiypour, K]]
	[[Category: Dauter, M]]		[[Category: Dauter, M]]

OCA at 07:30, 7 February 2016

2016-02-07T07:30:20Z

← Older revision		Revision as of 07:30, 7 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o7j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:12, 9 September 2015

2015-09-09T23:12:01Z

← Older revision		Revision as of 23:12, 9 September 2015
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	<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>		<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Erwinia_chrysanthemi Erwinia~~ chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Dickeya_chrysanthemi Dickeya chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://pdbe.org/1o7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 1o7j" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: ~~Erwinia~~ chrysanthemi]]		[[Category: Dickeya chrysanthemi]]
	[[Category: Aghaiypour, K]]		[[Category: Aghaiypour, K]]
	[[Category: Dauter, M]]		[[Category: Dauter, M]]

OCA at 16:01, 5 January 2015

2015-01-05T16:01:21Z

← Older revision		Revision as of 16:01, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>		<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: Erwinia chrysanthemi]]		[[Category: Erwinia chrysanthemi]]
	[[Category: Aghaiypour, K.]]		[[Category: Aghaiypour, K]]
	[[Category: Dauter, M.]]		[[Category: Dauter, M]]
	[[Category: Dauter, Z.]]		[[Category: Dauter, Z]]
	[[Category: Lubkowski, J.]]		[[Category: Lubkowski, J]]
	[[Category: Wlodawer, A.]]		[[Category: Wlodawer, A]]
	[[Category: Atomic resolution]]		[[Category: Atomic resolution]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: L-asparaginase]]		[[Category: L-asparaginase]]

OCA at 14:37, 28 September 2014

2014-09-28T14:37:25Z

← Older revision		Revision as of 14:37, 28 September 2014
Line 1:		Line 1:
	[[Image:~~1o7j~~.~~png~~\|~~left~~\|~~200px~~]]		==ATOMIC RESOLUTION STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE==
			<StructureSection load='1o7j' size='340' side='right' caption='[[1o7j]], [[Resolution\|resolution]] 1.00Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1O7J FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hfj\|1hfj]], [[1hfk\|1hfk]], [[1hfw\|1hfw]], [[1hg0\|1hg0]], [[1hg1\|1hg1]], [[1jsl\|1jsl]], [[1jsr\|1jsr]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Asparaginase Asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1o7j RCSB], [http://www.ebi.ac.uk/pdbsum/1o7j PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/1o7j_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			An X-ray structure of L-asparaginase from Erwinia chrysanthemi (ErA) has been refined at 1 A resolution to an R factor of below 0.1, using data collected on a synchrotron source. With four molecules of the enzyme consisting of 327 amino acids each, this crystal contains one of the largest asymmetric units of a protein refined to date at atomic resolution. Previously, structures of ErA and of related enzymes from other bacterial sources have been refined at resolutions not exceeding 1.7 A; thus, the present structure represents a very significant improvement in the quality of the available models of these proteins and should provide a good basis for future studies of the conformational variability of proteins, identification of subtle conformational features and corroboration of the stereochemical libraries, amongst other things. L-Asparaginases, which are enzymes that catalyze the hydrolysis of L-asparagine to aspartic acid, have been used for over 30 y as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia, although the details of the enzymatic reaction and substrate specificity have not yet been completely elucidated. This atomic resolution structure is a step in that direction.

	~~{{STRUCTURE_1o7j\| PDB=1o7j \| SCENE= }}~~		Atomic resolution structure of Erwinia chrysanthemi L-asparaginase.,Lubkowski J, Dauter M, Aghaiypour K, Wlodawer A, Dauter Z Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):84-92. Epub 2002, Dec 19. PMID:12499544<ref>PMID:12499544</ref>

	~~===ATOMIC RESOLUTION STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_12499544}}~~		==See Also==
			*[[Asparaginase\|Asparaginase]]
	==~~About this Structure~~==		== References ==
	[[~~1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA~~].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:012499544<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: Erwinia chrysanthemi]]		[[Category: Erwinia chrysanthemi]]

OCA: Protected "1o7j" [edit=sysop:move=sysop]

2012-12-12T21:53:10Z

Protected "1o7j" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:53, 12 December 2012
(No difference)

OCA at 21:53, 12 December 2012

2012-12-12T21:53:03Z

← Older revision		Revision as of 21:53, 12 December 2012
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	~~{{Seed}}~~
	[[Image:1o7j.png\|left\|200px]]		[[Image:1o7j.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_1o7j", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_1o7j\| PDB=1o7j \| SCENE= }}		{{STRUCTURE_1o7j\| PDB=1o7j \| SCENE= }}

	===ATOMIC RESOLUTION STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE===		===ATOMIC RESOLUTION STRUCTURE OF ERWINIA CHRYSANTHEMI L-ASPARAGINASE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_12499544}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 12499544 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_12499544}}		{{ABSTRACT_PUBMED_12499544}}

	==About this Structure==		==About this Structure==
	~~1O7J~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA].		[[1o7j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Erwinia_chrysanthemi Erwinia chrysanthemi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O7J OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~12499544~~</ref><references group="xtra"/>		<ref group="xtra">PMID:012499544</ref><references group="xtra"/>
	[[Category: Asparaginase]]		[[Category: Asparaginase]]
	[[Category: Erwinia chrysanthemi]]		[[Category: Erwinia chrysanthemi]]
Line 31:		Line 19:
	[[Category: Lubkowski, J.]]		[[Category: Lubkowski, J.]]
	[[Category: Wlodawer, A.]]		[[Category: Wlodawer, A.]]
	[[Category: Atomic resolution~~,hydrolase~~]]		[[Category: Atomic resolution]]
			[[Category: Hydrolase]]
	[[Category: L-asparaginase]]		[[Category: L-asparaginase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:16:31 2009''~~