1vb3 - Revision history

OCA at 00:00, 28 December 2023

2023-12-28T00:00:53Z

← Older revision		Revision as of 00:00, 28 December 2023
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	<StructureSection load='1vb3' size='340' side='right'caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1vb3' size='340' side='right'caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=KPA:2~~-~~OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https:~~/~~/en.wikipedia.org/wiki/Threonine_synthase Threonine synthase]~~, ~~with EC number [https~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1]~~ </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [https://pdbe.org/1vb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vb3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [https://pdbe.org/1vb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vb3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/THRC_ECOLI THRC_ECOLI]] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction.		[https://www.uniprot.org/uniprot/THRC_ECOLI THRC_ECOLI] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Threonine synthase]]~~		[[Category: Omi R]]
	[[Category: Omi, R]]
	~~[[Category: Lyase]]~~
	~~[[Category: Plp-dependent enzyme~~]]

OCA at 13:19, 13 October 2021

2021-10-13T13:19:13Z

← Older revision		Revision as of 13:19, 13 October 2021
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	<StructureSection load='1vb3' size='340' side='right'caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1vb3' size='340' side='right'caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [~~http~~://pdbe.org/1vb3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1vb3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1vb3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [https://pdbe.org/1vb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vb3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/THRC_ECOLI THRC_ECOLI]] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction.		[[https://www.uniprot.org/uniprot/THRC_ECOLI THRC_ECOLI]] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:53, 8 January 2020

2020-01-08T10:53:04Z

← Older revision		Revision as of 10:53, 8 January 2020
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	==Crystal Structure of Threonine Synthase from Escherichia coli==		==Crystal Structure of Threonine Synthase from Escherichia coli==
	<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1vb3' size='340' side='right'caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Threonine synthase]]		[[Category: Threonine synthase]]
	[[Category: Omi, R]]		[[Category: Omi, R]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]

OCA at 07:54, 4 April 2018

2018-04-04T07:54:20Z

← Older revision		Revision as of 07:54, 4 April 2018
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	==Crystal Structure of Threonine Synthase from Escherichia coli==		==Crystal Structure of Threonine Synthase from Escherichia coli==
	<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://pdbe.org/1vb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://pdbe.org/1vb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1vb3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vb3_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vb3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:59, 8 February 2016

2016-02-08T06:59:51Z

← Older revision		Revision as of 06:59, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vb3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 09:03, 10 September 2015

2015-09-10T09:03:33Z

← Older revision		Revision as of 09:03, 10 September 2015
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	<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://pdbe.org/1vb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Threonine synthase]]		[[Category: Threonine synthase]]
	[[Category: Omi, R]]		[[Category: Omi, R]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]

OCA at 21:29, 24 December 2014

2014-12-24T21:29:39Z

← Older revision		Revision as of 21:29, 24 December 2014
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/THRC_ECOLI THRC_ECOLI]] Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Threonine synthase]]		[[Category: Threonine synthase]]
	[[Category: Omi, R.]]		[[Category: Omi, R]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]

OCA at 21:42, 29 September 2014

2014-09-29T21:42:16Z

← Older revision		Revision as of 21:42, 29 September 2014
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	~~[[Image:1vb3.png\|left\|200px]]~~		==Crystal Structure of Threonine Synthase from Escherichia coli==
			<StructureSection load='1vb3' size='340' side='right' caption='[[1vb3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	~~{{STRUCTURE_1vb3\| PDB=1vb3 \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VB3 FirstGlance]. <br>
	===Crystal Structure of Threonine Synthase from Escherichia coli===		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPA:2-OXO-5-PHOSPHONOPENTANOIC+ACID'>KPA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Threonine_synthase Threonine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.1 4.2.3.1] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vb3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vb3 RCSB], [http://www.ebi.ac.uk/pdbsum/1vb3 PDBsum]</span></td></tr>
	==~~About this Structure~~==		<table>
	[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA].		== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vb3_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Threonine synthase]]		[[Category: Threonine synthase]]

OCA: Protected "1vb3" [edit=sysop:move=sysop]

2013-01-05T13:07:03Z

Protected "1vb3" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:07, 5 January 2013
(No difference)

OCA at 13:07, 5 January 2013

2013-01-05T13:07:01Z

← Older revision		Revision as of 13:07, 5 January 2013
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	~~{{Seed}}~~
	[[Image:1vb3.png\|left\|200px]]		[[Image:1vb3.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_1vb3", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_1vb3\| PDB=1vb3 \| SCENE= }}		{{STRUCTURE_1vb3\| PDB=1vb3 \| SCENE= }}

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	==About this Structure==		==About this Structure==
	~~1VB3~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA].		[[1vb3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VB3 OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Threonine synthase]]		[[Category: Threonine synthase]]
	[[Category: Omi, R.]]		[[Category: Omi, R.]]
			[[Category: Lyase]]
	[[Category: Plp-dependent enzyme]]		[[Category: Plp-dependent enzyme]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:01:09 2009''~~