2aqa - Revision history

OCA at 09:22, 22 May 2024

2024-05-22T09:22:59Z

← Older revision		Revision as of 09:22, 22 May 2024
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	==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==		==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
	<StructureSection load='2aqa' size='340' side='right'caption='[[2aqa~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2aqa' size='340' side='right'caption='[[2aqa]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>NOP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~4932 ATCC 18824])~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [https://pdbe.org/2aqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [https://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [https://pdbe.org/2aqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [https://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>		[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 18824]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Amare, A R.~~Ferre-D]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Hamma, T]]		[[Category: Ferre-D'Amare AR]]
	[[Category: Reichow~~, S L~~]]		[[Category: Hamma T]]
	[[Category: Varani, G]]		[[Category: Reichow SL]]
	~~[[Category: Nop10p]]~~		[[Category: Varani G]]
	~~[[Category: Rna binding protein~~]]

OCA at 08:36, 27 January 2021

2021-01-27T08:36:02Z

← Older revision		Revision as of 08:36, 27 January 2021
Line 1:		Line 1:

	==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==		==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
	<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2aqa' size='340' side='right'caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2AQA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [~~http~~://pdbe.org/2aqa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [https://pdbe.org/2aqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [https://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>		[[https://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
			[[Category: Large Structures]]
	[[Category: Amare, A R.Ferre-D]]		[[Category: Amare, A R.Ferre-D]]
	[[Category: Hamma, T]]		[[Category: Hamma, T]]

OCA at 07:17, 9 May 2018

2018-05-09T07:17:24Z

← Older revision		Revision as of 07:17, 9 May 2018
Line 1:		Line 1:

	==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==		==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
	<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://pdbe.org/2aqa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://pdbe.org/2aqa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2aqa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqa_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:41, 9 February 2016

2016-02-09T22:41:40Z

← Older revision		Revision as of 22:41, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aqa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:45, 11 September 2015

2015-09-11T02:45:56Z

← Older revision		Revision as of 02:45, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://pdbe.org/2aqa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2aqa" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Saccharomyces cerevisiae~~]]		[[Category: Atcc 18824]]
	[[Category: Amare, A R.Ferre-D]]		[[Category: Amare, A R.Ferre-D]]
	[[Category: Hamma, T]]		[[Category: Hamma, T]]

OCA at 10:02, 25 December 2014

2014-12-25T10:02:47Z

← Older revision		Revision as of 10:02, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/NOP10_YEAST NOP10_YEAST]] Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. Essential for growth.<ref>PMID:9843512</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Amare, A R.Ferre-D.]]		[[Category: Amare, A R.Ferre-D]]
	[[Category: Hamma, T.]]		[[Category: Hamma, T]]
	[[Category: Reichow, S L.]]		[[Category: Reichow, S L]]
	[[Category: Varani, G.]]		[[Category: Varani, G]]
	[[Category: Nop10p]]		[[Category: Nop10p]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]

OCA at 01:16, 30 September 2014

2014-09-30T01:16:51Z

← Older revision		Revision as of 01:16, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2aqa~~.~~png~~\|~~left~~\|~~200px~~]]		==NMR structural analysis of Nop10p from Saccharomyces cerevisiae==
			<StructureSection load='2aqa' size='340' side='right' caption='[[2aqa]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AQA FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NOP10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2aqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2aqa RCSB], [http://www.ebi.ac.uk/pdbsum/2aqa PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aqa_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Box H/ACA ribonucleoprotein particles (RNPs) catalyze RNA pseudouridylation and direct processing of ribosomal RNA, and are essential architectural components of vertebrate telomerases. H/ACA RNPs comprise four proteins and a multihelical RNA. Two proteins, Cbf5 and Nop10, suffice for basal enzymatic activity in an archaeal in vitro system. We now report their cocrystal structure at 1.95-A resolution. We find that archaeal Cbf5 can assemble with yeast Nop10 and with human telomerase RNA, consistent with the high sequence identity of the RNP components between archaea and eukarya. Thus, the Cbf5-Nop10 architecture is phylogenetically conserved. The structure shows how Nop10 buttresses the active site of Cbf5, and it reveals two basic troughs that bidirectionally extend the active site cleft. Mutagenesis results implicate an adjacent basic patch in RNA binding. This tripartite RNA-binding surface may function as a molecular bracket that organizes the multihelical H/ACA and telomerase RNAs.

	~~{{STRUCTURE_2aqa\| PDB=2aqa \| SCENE= }}~~		The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.,Hamma T, Reichow SL, Varani G, Ferre-D'Amare AR Nat Struct Mol Biol. 2005 Dec;12(12):1101-7. Epub 2005 Nov 15. PMID:16286935<ref>PMID:16286935</ref>

	~~===NMR structural analysis~~ of ~~Nop10p from Saccharomyces cerevisiae===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16286935}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2aqa]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016286935<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Amare, A R.Ferre-D.]]		[[Category: Amare, A R.Ferre-D.]]

OCA: Protected "2aqa" [edit=sysop:move=sysop]

2013-01-06T10:31:17Z

Protected "2aqa" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:31, 6 January 2013
(No difference)

OCA at 10:31, 6 January 2013

2013-01-06T10:31:15Z

← Older revision		Revision as of 10:31, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2aqa.png\|left\|200px]]		[[Image:2aqa.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2aqa", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2aqa\| PDB=2aqa \| SCENE= }}		{{STRUCTURE_2aqa\| PDB=2aqa \| SCENE= }}

	===NMR structural analysis of Nop10p from Saccharomyces cerevisiae===		===NMR structural analysis of Nop10p from Saccharomyces cerevisiae===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16286935}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16286935 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_16286935}}		{{ABSTRACT_PUBMED_16286935}}

	==About this Structure==		==About this Structure==
	~~2AQA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA].		[[2aqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16286935~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016286935</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Amare, A R.Ferre-D.]]		[[Category: Amare, A R.Ferre-D.]]
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	[[Category: Varani, G.]]		[[Category: Varani, G.]]
	[[Category: Nop10p]]		[[Category: Nop10p]]
			[[Category: Rna binding protein]]
	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 13:18:53 2009''~~

OCA at 11:18, 17 February 2009

2009-02-17T11:18:55Z

← Older revision		Revision as of 11:18, 17 February 2009
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	==About this Structure==		==About this Structure==
	2AQA is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA].		2AQA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQA OCA].

	==Reference==		==Reference==
	~~The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs., Hamma T, Reichow SL, Varani G, Ferre-D'Amare AR, Nat Struct Mol Biol. 2005 Dec;12(12):1101-7. Epub 2005 Nov 15.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16286935 16286935]~~		<ref group="xtra">PMID:16286935</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	~~[[Category: Single protein]]~~
	[[Category: Amare, A R.Ferre-D.]]		[[Category: Amare, A R.Ferre-D.]]
	[[Category: Hamma, T.]]		[[Category: Hamma, T.]]
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	[[Category: Nop10p]]		[[Category: Nop10p]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28~~ 17:52:~~49 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:18:53 2009''