2b2d - Revision history

OCA at 08:19, 25 October 2023

2023-10-25T08:19:08Z

← Older revision		Revision as of 08:19, 25 October 2023
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	<StructureSection load='2b2d' size='340' side='right'caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2b2d' size='340' side='right'caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacteriophage_ms2 Bacteriophage ms2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2bny\|2bny]]~~, [[~~1aq3~~\|~~1aq3~~]]~~, [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [https://pdbe.org/2b2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [https://www.ebi.ac.uk/pdbsum/2b2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [https://pdbe.org/2b2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [https://www.ebi.ac.uk/pdbsum/2b2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/~~COAT_BPMS2 COAT_BPMS2~~]~~] Forms~~ the ~~phage~~ shell~~; binds~~ to the ~~phage~~ RNA.		[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacteriophage ms2~~]]		[[Category: Escherichia phage MS2]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Adams~~, C J~~]]		[[Category: Adams CJ]]
	[[Category: Baron~~, A J~~]]		[[Category: Baron AJ]]
	[[Category: Grahn, E]]		[[Category: Grahn E]]
	[[Category: Helgstrand, C]]		[[Category: Helgstrand C]]
	[[Category: Horn~~, W T~~]]		[[Category: Horn WT]]
	[[Category: Lago, H]]		[[Category: Lago H]]
	[[Category: Liljas, L]]		[[Category: Liljas L]]
	[[Category: Peabody~~, D S~~]]		[[Category: Peabody DS]]
	[[Category: Phillips~~, S E.V~~]]		[[Category: Phillips SEV]]
	[[Category: Stockley~~, P G~~]]		[[Category: Stockley PG]]
	[[Category: Stonehouse~~, N J~~]]		[[Category: Stonehouse NJ]]
	[[Category: Tars, K]]		[[Category: Tars K]]
	~~[[Category: Capsid]]~~
	~~[[Category: Levivirus]]~~
	~~[[Category: Protein/rna]]~~
	~~[[Category: Virus-viral protein-rna complex]]~~
	~~[[Category: Virus/viral~~]]

OCA at 06:46, 10 November 2021

2021-11-10T06:46:23Z

← Older revision		Revision as of 06:46, 10 November 2021
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	<StructureSection load='2b2d' size='340' side='right'caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2b2d' size='340' side='right'caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [~~http~~://pdbe.org/2b2d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2b2d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2d ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [https://pdbe.org/2b2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [https://www.ebi.ac.uk/pdbsum/2b2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.		[[https://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:05, 19 February 2020

2020-02-19T08:05:06Z

← Older revision		Revision as of 08:05, 19 February 2020
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	==RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid==		==RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid==
	<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2b2d' size='340' side='right'caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage ms2]]		[[Category: Bacteriophage ms2]]
			[[Category: Large Structures]]
	[[Category: Adams, C J]]		[[Category: Adams, C J]]
	[[Category: Baron, A J]]		[[Category: Baron, A J]]

OCA at 06:29, 16 May 2018

2018-05-16T06:29:09Z

← Older revision		Revision as of 06:29, 16 May 2018
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	==RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid==		==RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid==
	<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
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	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://pdbe.org/2b2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://pdbe.org/2b2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2b2d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b2d_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b2d_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:55, 9 February 2016

2016-02-09T16:55:37Z

← Older revision		Revision as of 16:55, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b2d ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:17, 11 September 2015

2015-09-11T00:17:07Z

← Older revision		Revision as of 00:17, 11 September 2015
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	<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacterio_phage_ms2 Enterobacterio phage~~ ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://pdbe.org/2b2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2b2d" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Enterobacterio phage~~ ms2]]		[[Category: Bacteriophage ms2]]
	[[Category: Adams, C J]]		[[Category: Adams, C J]]
	[[Category: Baron, A J]]		[[Category: Baron, A J]]

OCA at 08:13, 25 December 2014

2014-12-25T08:13:25Z

← Older revision		Revision as of 08:13, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J]]
	[[Category: Baron, A J.]]		[[Category: Baron, A J]]
	[[Category: Grahn, E.]]		[[Category: Grahn, E]]
	[[Category: Helgstrand, C.]]		[[Category: Helgstrand, C]]
	[[Category: Horn, W T.]]		[[Category: Horn, W T]]
	[[Category: Lago, H.]]		[[Category: Lago, H]]
	[[Category: Liljas, L.]]		[[Category: Liljas, L]]
	[[Category: Peabody, D S.]]		[[Category: Peabody, D S]]
	[[Category: Phillips, S E.V.]]		[[Category: Phillips, S E.V]]
	[[Category: Stockley, P G.]]		[[Category: Stockley, P G]]
	[[Category: Stonehouse, N J.]]		[[Category: Stonehouse, N J]]
	[[Category: Tars, K.]]		[[Category: Tars, K]]
	[[Category: Capsid]]		[[Category: Capsid]]
	[[Category: Levivirus]]		[[Category: Levivirus]]

OCA at 09:24, 3 October 2014

2014-10-03T09:24:13Z

← Older revision		Revision as of 09:24, 3 October 2014
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	~~{{STRUCTURE_2b2d\| PDB=2b2d \| SCENE= }}~~		==RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid==
	===RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid===		<StructureSection load='2b2d' size='340' side='right' caption='[[2b2d]], [[Resolution\|resolution]] 2.90Å' scene=''>
	~~{{ABSTRACT_PUBMED_16531233}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2b2d]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B2D FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bny\|2bny]], [[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1dzs\|1dzs]], [[1e6t\|1e6t]], [[2b2e\|2b2e]], [[2b2g\|2b2g]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b2d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2b2d RCSB], [http://www.ebi.ac.uk/pdbsum/2b2d PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b2d_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Sequence-specific interactions between RNA stem-loops and coat protein (CP) subunits play vital roles in the life cycles of the RNA bacteriophages, e.g., by allowing translational repression of their replicase cistrons and tagging their own RNA genomes for encapsidation. The CPs of bacteriophages Qbeta and MS2 each discriminate in favor of their cognate translational operators, even in the presence of closely related operators from other phages in vivo. Discrete mutations within the MS2 CP have been shown to relax this discrimination in vitro. We have determined the structures of eight complexes between such mutants and both MS2 and Qbeta stem-loops with X-ray crystallography. In conjunction with previously determined in vivo repression data, the structures enable us to propose the molecular basis for the discrimination mechanism.

	~~==Function==~~		Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2.,Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ, Lago H, Adams CJ, Peabody DS, Phillips SE, Stonehouse NJ, Liljas L, Stockley PG Structure. 2006 Mar;14(3):487-95. PMID:16531233<ref>PMID:16531233</ref>
	~~[[http://www~~.~~uniprot~~.~~org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell~~; ~~binds to the phage RNA~~.

	~~==About this Structure==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[2b2d]] is~~ a ~~5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2B2D OCA].~~		</div>
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:016531233</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J.]]

OCA at 08:47, 23 April 2014

2014-04-23T08:47:05Z

← Older revision		Revision as of 08:47, 23 April 2014
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	~~[[Image:2b2d.png\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2b2d", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2b2d\| PDB=2b2d \| SCENE= }}		{{STRUCTURE_2b2d\| PDB=2b2d \| SCENE= }}

	===RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid===		===RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid===
			{{ABSTRACT_PUBMED_16531233}}

			==Function==
	~~<!--~~		[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16531233}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 16531233 is~~ the ~~PubMed ID number~~.
	~~-->~~
	~~{{ABSTRACT_PUBMED_16531233}}~~

	==About this Structure==		==About this Structure==
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	==Reference==		==Reference==
	<ref group="xtra">PMID:016531233</ref><references group="xtra"/>		<ref group="xtra">PMID:016531233</ref><references group="xtra"/><references/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Adams, C J.]]		[[Category: Adams, C J.]]

OCA: Protected "2b2d" [edit=sysop:move=sysop]

2011-12-14T10:51:29Z

Protected "2b2d" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:51, 14 December 2011
(No difference)