2bbj - Revision history

OCA at 07:36, 23 August 2023

2023-08-23T07:36:22Z

← Older revision		Revision as of 07:36, 23 August 2023
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	<StructureSection load='2bbj' size='340' side='right'caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>		<StructureSection load='2bbj' size='340' side='right'caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2bbh~~\|~~2bbh~~]]~~</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [https://pdbe.org/2bbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [https://www.ebi.ac.uk/pdbsum/2bbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [https://pdbe.org/2bbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [https://www.ebi.ac.uk/pdbsum/2bbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CORA_THEMA CORA_THEMA]] Mediates influx of magnesium ions (By similarity).		[https://www.uniprot.org/uniprot/CORA_THEMA CORA_THEMA] Mediates influx of magnesium ions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 43589]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bochkarev, A]]		[[Category: Thermotoga maritima]]
	[[Category: Dobrovetsky, E]]		[[Category: Bochkarev A]]
	[[Category: Edwards~~, A M~~]]		[[Category: Dobrovetsky E]]
	[[Category: Joachimiak, A]]		[[Category: Edwards AM]]
	[[Category: Khutoreskaya, G]]		[[Category: Joachimiak A]]
	[[Category: Koth~~, C M~~]]		[[Category: Khutoreskaya G]]
	[[Category: Lunin~~, V V~~]]		[[Category: Koth CM]]
	[[Category: Maguire~~, M E]]~~		[[Category: Lunin VV]]
	~~[[Category: Structural genomic~~]]		[[Category: Maguire ME]]
	[[Category: Zhang, R]]		[[Category: Zhang R]]
	~~[[Category: Membrane]]~~
	~~[[Category: Metal transport-membrane protein complex]]~~
	~~[[Category: Mg]]~~
	~~[[Category: Pentamer]]~~
	~~[[Category: Sgc]]~~
	~~[[Category: Transporter~~]]

OCA at 13:07, 24 November 2021

2021-11-24T13:07:30Z

← Older revision		Revision as of 13:07, 24 November 2021
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	<StructureSection load='2bbj' size='340' side='right'caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>		<StructureSection load='2bbj' size='340' side='right'caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bbh\|2bbh]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [~~http~~://pdbe.org/2bbj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bbj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [https://pdbe.org/2bbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [https://www.ebi.ac.uk/pdbsum/2bbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CORA_THEMA CORA_THEMA]] Mediates influx of magnesium ions (By similarity).		[[https://www.uniprot.org/uniprot/CORA_THEMA CORA_THEMA]] Mediates influx of magnesium ions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:58, 19 February 2020

2020-02-19T07:58:15Z

← Older revision		Revision as of 07:58, 19 February 2020
Line 1:		Line 1:

	==Crystal structure of the CorA Mg2+ transporter==		==Crystal structure of the CorA Mg2+ transporter==
	<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>		<StructureSection load='2bbj' size='340' side='right'caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
			[[Category: Large Structures]]
	[[Category: Bochkarev, A]]		[[Category: Bochkarev, A]]
	[[Category: Dobrovetsky, E]]		[[Category: Dobrovetsky, E]]

OCA at 06:18, 16 May 2018

2018-05-16T06:18:46Z

← Older revision		Revision as of 06:18, 16 May 2018
Line 1:		Line 1:

	==Crystal structure of the CorA Mg2+ transporter==		==Crystal structure of the CorA Mg2+ transporter==
	<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>		<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://pdbe.org/2bbj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://pdbe.org/2bbj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bbj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/2bbj_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/2bbj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bbj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:23, 11 September 2015

2015-09-11T14:23:50Z

← Older revision		Revision as of 14:23, 11 September 2015
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	<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>		<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://pdbe.org/2bbj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CORA_THEMA CORA_THEMA]] Mediates influx of magnesium ions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bbj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Thermotoga maritima~~]]		[[Category: Atcc 43589]]
	[[Category: Bochkarev, A]]		[[Category: Bochkarev, A]]
	[[Category: Dobrovetsky, E]]		[[Category: Dobrovetsky, E]]

OCA at 10:04, 8 January 2015

2015-01-08T10:04:00Z

← Older revision		Revision as of 10:04, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Bochkarev, A.]]		[[Category: Bochkarev, A]]
	[[Category: Dobrovetsky, E.]]		[[Category: Dobrovetsky, E]]
	[[Category: Edwards, A M.]]		[[Category: Edwards, A M]]
	[[Category: Joachimiak, A.]]		[[Category: Joachimiak, A]]
	[[Category: Khutoreskaya, G.]]		[[Category: Khutoreskaya, G]]
	[[Category: Koth, C M.]]		[[Category: Koth, C M]]
	[[Category: Lunin, V V.]]		[[Category: Lunin, V V]]
	[[Category: Maguire, M E.]]		[[Category: Maguire, M E]]
	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]		[[Category: Structural genomic]]
	[[Category: Zhang, R.]]		[[Category: Zhang, R]]
	[[Category: Membrane]]		[[Category: Membrane]]
	[[Category: Metal transport-membrane protein complex]]		[[Category: Metal transport-membrane protein complex]]
Line 44:		Line 44:
	[[Category: Pentamer]]		[[Category: Pentamer]]
	[[Category: Sgc]]		[[Category: Sgc]]
	~~[[Category: Structural genomic]]~~
	~~[[Category: Structural genomics consortium]]~~
	[[Category: Transporter]]		[[Category: Transporter]]

OCA at 00:49, 30 September 2014

2014-09-30T00:49:07Z

← Older revision		Revision as of 00:49, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2bbj~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of the CorA Mg2+ transporter==
			<StructureSection load='2bbj' size='340' side='right' caption='[[2bbj]], [[Resolution\|resolution]] 3.90Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BBJ FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bbh\|2bbh]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bbj RCSB], [http://www.ebi.ac.uk/pdbsum/2bbj PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/2bbj_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The magnesium ion, Mg2+, is essential for myriad biochemical processes and remains the only major biological ion whose transport mechanisms remain unknown. The CorA family of magnesium transporters is the primary Mg2+ uptake system of most prokaryotes and a functional homologue of the eukaryotic mitochondrial magnesium transporter. Here we determine crystal structures of the full-length Thermotoga maritima CorA in an apparent closed state and its isolated cytoplasmic domain at 3.9 A and 1.85 A resolution, respectively. The transporter is a funnel-shaped homopentamer with two transmembrane helices per monomer. The channel is formed by an inner group of five helices and putatively gated by bulky hydrophobic residues. The large cytoplasmic domain forms a funnel whose wide mouth points into the cell and whose walls are formed by five long helices that are extensions of the transmembrane helices. The cytoplasmic neck of the pore is surrounded, on the outside of the funnel, by a ring of highly conserved positively charged residues. Two negatively charged helices in the cytoplasmic domain extend back towards the membrane on the outside of the funnel and abut the ring of positive charge. An apparent Mg2+ ion was bound between monomers at a conserved site in the cytoplasmic domain, suggesting a mechanism to link gating of the pore to the intracellular concentration of Mg2+.

	~~{{STRUCTURE_2bbj\| PDB=2bbj \| SCENE= }}~~		Crystal structure of the CorA Mg2+ transporter.,Lunin VV, Dobrovetsky E, Khutoreskaya G, Zhang R, Joachimiak A, Doyle DA, Bochkarev A, Maguire ME, Edwards AM, Koth CM Nature. 2006 Apr 6;440(7085):833-7. PMID:16598263<ref>PMID:16598263</ref>

	~~===Crystal structure~~ of the ~~CorA Mg2+ transporter===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16598263}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2bbj]] is a 5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermotoga_maritima Thermotoga maritima]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016598263<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Bochkarev, A.]]		[[Category: Bochkarev, A.]]

OCA: Protected "2bbj" [edit=sysop:move=sysop]

2013-01-06T10:08:56Z

Protected "2bbj" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:08, 6 January 2013
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OCA at 10:08, 6 January 2013

2013-01-06T10:08:53Z

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	~~{{Seed}}~~
	[[Image:2bbj.png\|left\|200px]]		[[Image:2bbj.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2bbj", creates the "Structure Box" on the page.~~
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	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
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	{{STRUCTURE_2bbj\| PDB=2bbj \| SCENE= }}		{{STRUCTURE_2bbj\| PDB=2bbj \| SCENE= }}

	===Crystal structure of the CorA Mg2+ transporter===		===Crystal structure of the CorA Mg2+ transporter===


	~~<!--~~
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	{{ABSTRACT_PUBMED_16598263}}		{{ABSTRACT_PUBMED_16598263}}

	==About this Structure==		==About this Structure==
	~~2BBJ~~ is a 5 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA].		[[2bbj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16598263~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016598263</ref><references group="xtra"/>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Bochkarev, A.]]		[[Category: Bochkarev, A.]]
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	[[Category: Zhang, R.]]		[[Category: Zhang, R.]]
	[[Category: Membrane]]		[[Category: Membrane]]
			[[Category: Metal transport-membrane protein complex]]
	[[Category: Mg]]		[[Category: Mg]]
	[[Category: Pentamer]]		[[Category: Pentamer]]
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	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
	[[Category: Transporter]]		[[Category: Transporter]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:29:08 2009''~~

OCA at 22:29, 17 February 2009

2009-02-17T22:29:09Z

← Older revision		Revision as of 22:29, 17 February 2009
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	==About this Structure==		==About this Structure==
	2BBJ is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA].		2BBJ is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBJ OCA].

	==Reference==		==Reference==
	Crystal structure of the CorA Mg2+ transporter., Lunin VV, Dobrovetsky E, Khutoreskaya G, Zhang R, Joachimiak A, Doyle DA, Bochkarev A, Maguire ME, Edwards AM, Koth CM, Nature. 2006 Apr 6;440(7085):833-7. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16598263 16598263]~~		<ref group="xtra">PMID:16598263</ref><references group="xtra"/>
	~~[[Category: Single protein]]~~
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Bochkarev, A.]]		[[Category: Bochkarev, A.]]
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	[[Category: Transporter]]		[[Category: Transporter]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul~~ 29 ~~07:52~~:~~00 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:29:08 2009''