2bcb - Revision history

OCA at 09:24, 22 May 2024

2024-05-22T09:24:35Z

← Older revision		Revision as of 09:24, 22 May 2024
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	==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==		==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==
	<StructureSection load='2bcb' size='340' side='right'caption='[[2bcb~~]], [[NMR_Ensembles_of_Models \| 32 NMR models~~]]' scene=''>		<StructureSection load='2bcb' size='340' side='right'caption='[[2bcb]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[2bca\|2bca]]</div~~></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [https://pdbe.org/2bcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [https://www.ebi.ac.uk/pdbsum/2bcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [https://pdbe.org/2bcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [https://www.ebi.ac.uk/pdbsum/2bcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcb ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/S100G_BOVIN S100G_BOVIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bovin~~]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Akke, M]]		[[Category: Akke M]]
	[[Category: Chazin~~, W J~~]]		[[Category: Chazin WJ]]
	[[Category: Kordel, J]]		[[Category: Kordel J]]
	[[Category: Skelton~~, N J]]~~		[[Category: Skelton NJ]]
	~~[[Category: Calcium-binding protein~~]]

OCA at 13:07, 24 November 2021

2021-11-24T13:07:56Z

← Older revision		Revision as of 13:07, 24 November 2021
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	<StructureSection load='2bcb' size='340' side='right'caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>		<StructureSection load='2bcb' size='340' side='right'caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bca\|2bca]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [~~http~~://pdbe.org/2bcb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bcb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [https://pdbe.org/2bcb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [https://www.ebi.ac.uk/pdbsum/2bcb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcb ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:15, 19 February 2020

2020-02-19T08:15:29Z

← Older revision		Revision as of 08:15, 19 February 2020
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	==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==		==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==
	<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>		<StructureSection load='2bcb' size='340' side='right'caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[S100 ~~protein~~\|S100 ~~protein~~]]		*[[S100 proteins 3D structures\|S100 proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bovin]]		[[Category: Bovin]]
			[[Category: Large Structures]]
	[[Category: Akke, M]]		[[Category: Akke, M]]
	[[Category: Chazin, W J]]		[[Category: Chazin, W J]]

OCA at 06:45, 16 May 2018

2018-05-16T06:45:37Z

← Older revision		Revision as of 06:45, 16 May 2018
Line 1:		Line 1:

	==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==		==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==
	<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>		<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>
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	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://pdbe.org/2bcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://pdbe.org/2bcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bcb ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bcb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:15, 11 September 2015

2015-09-11T13:15:35Z

← Older revision		Revision as of 13:15, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>		<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://pdbe.org/2bcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bcb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bos taurus~~]]		[[Category: Bovin]]
	[[Category: Akke, M]]		[[Category: Akke, M]]
	[[Category: Chazin, W J]]		[[Category: Chazin, W J]]

OCA at 10:33, 8 January 2015

2015-01-08T10:33:38Z

← Older revision		Revision as of 10:33, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Akke, M.]]		[[Category: Akke, M]]
	[[Category: Chazin, W J.]]		[[Category: Chazin, W J]]
	[[Category: Kordel, J.]]		[[Category: Kordel, J]]
	[[Category: Skelton, N J.]]		[[Category: Skelton, N J]]
	[[Category: Calcium-binding protein]]		[[Category: Calcium-binding protein]]

OCA at 02:56, 30 September 2014

2014-09-30T02:56:23Z

← Older revision		Revision as of 02:56, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2bcb~~.~~png~~\|~~left~~\|~~200px~~]]		==HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K==
			<StructureSection load='2bcb' size='340' side='right' caption='[[2bcb]], [[NMR_Ensembles_of_Models \| 32 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BCB FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bca\|2bca]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bcb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bcb RCSB], [http://www.ebi.ac.uk/pdbsum/2bcb PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/2bcb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The three-dimensional solution structure of calcium-loaded calbindin D9k has been determined using experimental constraints obtained from nuclear magnetic resonance spectroscopy. A total of 1176 constraints (16 per residue overall, 32 per residue for the core residues) was used for the final refinement, including 1002 distance and 174 dihedral angle constraints. In addition, 23 hydrogen bond constraints were used for the generation of initial structures. Stereospecific assignments were made for 37 of 61 (61%) prochiral methylene protons and the methyl groups of all three valine residues and five out of 12 leucine residues. These constraints were used as input for a series of calculations of three-dimensional structures using a combination of distance geometry and restrained molecular dynamics. The 33 best structures selected for further analysis have no distance constraint violations greater than 0.3 A and good local geometries as reflected by low total energies (< or = -1014 kcal/mol in the AMBER 4.0 force field). The core of the protein consists of four well-defined helices with root-mean-square deviations from the average of 0.45 A for the N, C alpha and C' backbone atoms. These helices are packed in an antiparallel fashion to form two helix-loop-helix calcium-binding motifs, termed EF-hands. The two EF-hands are joined at one end by a ten-residue linker segment, and at the other by a short beta-type interaction between the two calcium-binding loops. Overall, the average solution structure of calbindin D9k is very similar to the crystal structure, with a pairwise root-mean-square deviation of 0.85 A for the N, C alpha and C' backbone atoms of the four helices. The differences that are observed between the solution and the crystal structures are attributed to specific crystal contacts, increased side-chain flexibility in solution, or artifacts arising from molecular dynamics refinement of the solution structures in vacuo.

	~~{{STRUCTURE_2bcb\| PDB=2bcb \| SCENE= }}~~		High-resolution structure of calcium-loaded calbindin D9k.,Kordel J, Skelton NJ, Akke M, Chazin WJ J Mol Biol. 1993 Jun 5;231(3):711-34. PMID:8515447<ref>PMID:8515447</ref>

	~~===HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_8515447}}~~		==See Also==
			*[[S100 protein\|S100 protein]]
	==~~About this Structure~~==		== References ==
	[[~~2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus~~]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA~~].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:008515447<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Akke, M.]]		[[Category: Akke, M.]]

OCA: Protected "2bcb" [edit=sysop:move=sysop]

2013-01-06T12:06:53Z

Protected "2bcb" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:06, 6 January 2013
(No difference)

OCA at 12:06, 6 January 2013

2013-01-06T12:06:50Z

← Older revision		Revision as of 12:06, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2bcb.png\|left\|200px]]		[[Image:2bcb.png\|left\|200px]]

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	{{STRUCTURE_2bcb\| PDB=2bcb \| SCENE= }}		{{STRUCTURE_2bcb\| PDB=2bcb \| SCENE= }}

	===HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K===		===HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K===


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	~~The line below this paragraph, {{ABSTRACT_PUBMED_8515447}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_8515447}}		{{ABSTRACT_PUBMED_8515447}}

	==About this Structure==		==About this Structure==
	~~2BCB~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA].		[[2bcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~8515447~~</ref><references group="xtra"/>		<ref group="xtra">PMID:008515447</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Akke, M.]]		[[Category: Akke, M.]]
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	[[Category: Skelton, N J.]]		[[Category: Skelton, N J.]]
	[[Category: Calcium-binding protein]]		[[Category: Calcium-binding protein]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 22:27:02 2009''~~

OCA at 20:27, 17 February 2009

2009-02-17T20:27:03Z

← Older revision		Revision as of 20:27, 17 February 2009
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	==About this Structure==		==About this Structure==
	2BCB is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA].		2BCB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BCB OCA].

	==Reference==		==Reference==
	~~High-resolution structure of calcium-loaded calbindin D9k., Kordel J, Skelton NJ, Akke M, Chazin WJ, J Mol Biol. 1993 Jun 5;231(3):711-34.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/8515447 8515447]~~		<ref group="xtra">PMID:8515447</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	~~[[Category: Single protein]]~~
	[[Category: Akke, M.]]		[[Category: Akke, M.]]
	[[Category: Chazin, W J.]]		[[Category: Chazin, W J.]]
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	[[Category: Calcium-binding protein]]		[[Category: Calcium-binding protein]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 06~~:39:~~48 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 22:27:02 2009''