2bmt - Revision history

OCA at 07:46, 23 October 2024

2024-10-23T07:46:43Z

← Older revision		Revision as of 07:46, 23 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 25 models</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [https://pdbe.org/2bmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [https://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [https://pdbe.org/2bmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [https://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>

OCA at 06:33, 19 July 2023

2023-07-19T06:33:18Z

← Older revision		Revision as of 06:33, 19 July 2023
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	==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==		==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==
	<StructureSection load='2bmt' size='340' side='right'caption='[[2bmt~~]], [[NMR_Ensembles_of_Models \| 25 NMR models~~]]' scene=''>		<StructureSection load='2bmt' size='340' side='right'caption='[[2bmt]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buthus_martensi Buthus martensi~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [https://pdbe.org/2bmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [https://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [https://pdbe.org/2bmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [https://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/KAX16_MESMA KAX16_MESMA]] Potent blocker of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1.3/KCNA3 (PubMed:9354615) and ERG1/Kv11.1/KCNH2 (PubMed:18687312)).		[https://www.uniprot.org/uniprot/KAX16_MESMA KAX16_MESMA] Potent blocker of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1.3/KCNA3 (PubMed:9354615) and ERG1/Kv11.1/KCNH2 (PubMed:18687312)).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Buthus martensi]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Blanc, E]]		[[Category: Mesobuthus martensii]]
	[[Category: Bornet, O]]		[[Category: Blanc E]]
	[[Category: Darbon, H]]		[[Category: Bornet O]]
	[[Category: Nakajima, T]]		[[Category: Darbon H]]
	[[Category: Romi-Lebrun, R]]		[[Category: Nakajima T]]
	~~[[Category: Buthus martensii]]~~		[[Category: Romi-Lebrun R]]
	~~[[Category: Large conductance potassium channel]]~~
	~~[[Category: Neurotoxin]]~~
	~~[[Category: Scorpion]]~~
	~~[[Category: Voltage gated potassium channel~~]]

OCA at 13:38, 13 October 2021

2021-10-13T13:38:39Z

← Older revision		Revision as of 13:38, 13 October 2021
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	<StructureSection load='2bmt' size='340' side='right'caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bmt' size='340' side='right'caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [~~http~~://pdbe.org/2bmt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [https://pdbe.org/2bmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [https://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/KAX16_MESMA KAX16_MESMA]] Potent blocker of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1.3/KCNA3 (PubMed:9354615) and ERG1/Kv11.1/KCNH2 (PubMed:18687312)).		[[https://www.uniprot.org/uniprot/KAX16_MESMA KAX16_MESMA]] Potent blocker of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1.3/KCNA3 (PubMed:9354615) and ERG1/Kv11.1/KCNH2 (PubMed:18687312)).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:39, 25 December 2019

2019-12-25T09:39:29Z

← Older revision		Revision as of 09:39, 25 December 2019
Line 1:		Line 1:

	==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==		==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==
	<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bmt' size='340' side='right'caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
	*[[Potassium channel toxin\|Potassium channel toxin]]		*[[Potassium channel toxin 3D structures\|Potassium channel toxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Buthus martensi]]		[[Category: Buthus martensi]]
			[[Category: Large Structures]]
	[[Category: Blanc, E]]		[[Category: Blanc, E]]
	[[Category: Bornet, O]]		[[Category: Bornet, O]]

OCA at 06:16, 16 May 2018

2018-05-16T06:16:43Z

← Older revision		Revision as of 06:16, 16 May 2018
Line 1:		Line 1:

	==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==		==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==
	<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [http://pdbe.org/2bmt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [http://www.ebi.ac.uk/pdbsum/2bmt PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [http://pdbe.org/2bmt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [http://www.ebi.ac.uk/pdbsum/2bmt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 15:30, 10 September 2015

2015-09-10T15:30:47Z

← Older revision		Revision as of 15:30, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mesobuthus_martensii Mesobuthus martensii~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buthus_martensi Buthus martensi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [http://www.ebi.ac.uk/pdbsum/2bmt PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [http://pdbe.org/2bmt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [http://www.ebi.ac.uk/pdbsum/2bmt PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/KAX16_MESMA KAX16_MESMA]] Potent blocker of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1.3/KCNA3 (PubMed:9354615) and ERG1/Kv11.1/KCNH2 (PubMed:18687312)).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bmt" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Mesobuthus martensii~~]]		[[Category: Buthus martensi]]
	[[Category: Blanc, E]]		[[Category: Blanc, E]]
	[[Category: Bornet, O]]		[[Category: Bornet, O]]

OCA at 13:55, 17 December 2014

2014-12-17T13:55:24Z

← Older revision		Revision as of 13:55, 17 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_2bmt\| PDB=2bmt \| SCENE= }}~~		==SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES==
	===SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES===		<StructureSection load='2bmt' size='340' side='right' caption='[[2bmt]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	~~{{ABSTRACT_PUBMED_9730813}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BMT FirstGlance]. <br>
			</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bmt RCSB], [http://www.ebi.ac.uk/pdbsum/2bmt PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The solution structure of BmTX2 purified from the venom of the Chinese Buthid Buthus martensi has been determined by 2D NMR spectroscopy techniques which led to the description of its 3D conformation. The structure consists of a triple-stranded beta-sheet connected to a helical structure. This helix encompasses 10 residues, from 11 to 20, begins with a turn of 310 helix, and ends with an alpha helix. The three strands of beta sheet comprise residues 2-6, with a bulge covering residues 4 and 5, 26-29, and 32-35, with a type I' beta turn centered on residues 30-31. We also characterized the solution structure of BmTX1. The two toxins which are potent blockers of both large-conductance calcium-activated potassium channels (BKCa channels) and voltage-gated potassium channels (Kv1. 3) are highly superimposable and possess the same structural characteristics. Analysis of these structures allows us to hypothesize that, besides the main surface of interaction described by the functional map of charybdotoxin, one can expect that the binding of scorpion toxins on BKCa channels may involve residues on the edge of this surface.

	~~==About this Structure==~~		Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels.,Blanc E, Romi-Lebrun R, Bornet O, Nakajima T, Darbon H Biochemistry. 1998 Sep 8;37(36):12412-8. PMID:9730813<ref>PMID:9730813</ref>
	~~[[2bmt]] is a 1 chain~~ structure ~~with sequence~~ from ~~[http://en~~.~~wikipedia~~.~~org/wiki/Mesobuthus_martensii Mesobuthus martensii]~~. ~~Full experimental information is available from [http~~://~~oca~~.~~weizmann~~.ac.~~il/oca-bin~~/~~ocashort?id=2BMT OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[Potassium channel toxin\|Potassium channel toxin]]		*[[Potassium channel toxin\|Potassium channel toxin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:009730813<~~/~~ref~~><~~ref group="xtra">PMID:010631983</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Mesobuthus martensii]]		[[Category: Mesobuthus martensii]]
	[[Category: Blanc, E.]]		[[Category: Blanc, E]]
	[[Category: Bornet, O.]]		[[Category: Bornet, O]]
	[[Category: Darbon, H.]]		[[Category: Darbon, H]]
	[[Category: Nakajima, T.]]		[[Category: Nakajima, T]]
	[[Category: Romi-Lebrun, R.]]		[[Category: Romi-Lebrun, R]]
	[[Category: Buthus martensii]]		[[Category: Buthus martensii]]
	[[Category: Large conductance potassium channel]]		[[Category: Large conductance potassium channel]]

OCA at 10:49, 11 March 2013

2013-03-11T10:49:06Z

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	~~[[Image:2bmt.png\|left\|200px]]~~

	{{STRUCTURE_2bmt\| PDB=2bmt \| SCENE= }}		{{STRUCTURE_2bmt\| PDB=2bmt \| SCENE= }}

	===SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES===		===SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES===

	{{ABSTRACT_PUBMED_9730813}}		{{ABSTRACT_PUBMED_9730813}}

OCA: Protected "2bmt" [edit=sysop:move=sysop]

2013-01-06T11:38:30Z

Protected "2bmt" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:38, 6 January 2013
(No difference)

OCA at 11:38, 6 January 2013

2013-01-06T11:38:27Z

← Older revision		Revision as of 11:38, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2bmt.png\|left\|200px]]		[[Image:2bmt.png\|left\|200px]]

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	{{STRUCTURE_2bmt\| PDB=2bmt \| SCENE= }}		{{STRUCTURE_2bmt\| PDB=2bmt \| SCENE= }}

	===SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES===		===SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES===


	~~<!--~~
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	==About this Structure==		==About this Structure==
	~~2BMT is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA].		[[2bmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMT OCA].

			==See Also==
			*[[Potassium channel toxin\|Potassium channel toxin]]

	==Reference==		==Reference==
	Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels., Blanc E, Romi-Lebrun R, Bornet O, Nakajima T, Darbon H, Biochemistry. 1998 Sep 8;37(36):~~12412-8.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~9730813 9730813]~~		<ref group="xtra">PMID:009730813</ref><ref group="xtra">PMID:010631983</ref><references group="xtra"/>
	[[Category: Mesobuthus martensii]]		[[Category: Mesobuthus martensii]]
	~~[[Category: Single protein]]~~
	[[Category: Blanc, E.]]		[[Category: Blanc, E.]]
	[[Category: Bornet, O.]]		[[Category: Bornet, O.]]
Line 34:		Line 24:
	[[Category: Large conductance potassium channel]]		[[Category: Large conductance potassium channel]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]
	~~[[Category: Nmr]]~~
	[[Category: Scorpion]]		[[Category: Scorpion]]
	~~[[Category: Structure]]~~
	[[Category: Voltage gated potassium channel]]		[[Category: Voltage gated potassium channel]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:57:01 2008''~~