2bpr - Revision history

OCA at 09:24, 22 May 2024

2024-05-22T09:24:47Z

← Older revision		Revision as of 09:24, 22 May 2024
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	==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==		==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==
	<StructureSection load='2bpr' size='340' side='right'caption='[[2bpr~~]], [[NMR_Ensembles_of_Models \| 25 NMR models~~]]' scene=''>		<StructureSection load='2bpr' size='340' side='right'caption='[[2bpr]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [https://pdbe.org/2bpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [https://www.ebi.ac.uk/pdbsum/2bpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpr ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [https://pdbe.org/2bpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [https://www.ebi.ac.uk/pdbsum/2bpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]		[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Flynn~~, G C~~]]		[[Category: Flynn GC]]
	[[Category: Hu, W]]		[[Category: Hu W]]
	[[Category: Kurochkin~~, A V~~]]		[[Category: Kurochkin AV]]
	[[Category: Pang, Y]]		[[Category: Pang Y]]
	[[Category: Wang, H]]		[[Category: Wang H]]
	[[Category: Zuiderweg~~, E R.P]]~~		[[Category: Zuiderweg ERP]]
	~~[[Category: Hsp70]]~~
	~~[[Category: Molecular chaperone]]~~
	~~[[Category: Peptide binding]]~~
	~~[[Category: Protein folding~~]]

OCA at 13:15, 24 November 2021

2021-11-24T13:15:39Z

← Older revision		Revision as of 13:15, 24 November 2021
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	<StructureSection load='2bpr' size='340' side='right'caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bpr' size='340' side='right'caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [~~http~~://pdbe.org/2bpr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bpr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpr ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [https://pdbe.org/2bpr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [https://www.ebi.ac.uk/pdbsum/2bpr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]		[[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:11, 19 February 2020

2020-02-19T08:11:13Z

← Older revision		Revision as of 08:11, 19 February 2020
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	==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==		==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==
	<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bpr' size='340' side='right'caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
Line 29:		Line 29:

	==See Also==		==See Also==
	*[[Heat Shock ~~Proteins~~\|Heat Shock ~~Proteins~~]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Flynn, G C]]		[[Category: Flynn, G C]]
	[[Category: Hu, W]]		[[Category: Hu, W]]

OCA at 06:38, 16 May 2018

2018-05-16T06:38:58Z

← Older revision		Revision as of 06:38, 16 May 2018
Line 1:		Line 1:

	==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==		==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==
	<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://pdbe.org/2bpr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://pdbe.org/2bpr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/2bpr_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/2bpr_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:27, 9 February 2016

2016-02-09T06:27:20Z

← Older revision		Revision as of 06:27, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bpr ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 19:29, 10 September 2015

2015-09-10T19:29:57Z

← Older revision		Revision as of 19:29, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://pdbe.org/2bpr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bpr" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Flynn, G C]]		[[Category: Flynn, G C]]
	[[Category: Hu, W]]		[[Category: Hu, W]]

OCA at 05:02, 25 December 2014

2014-12-25T05:02:07Z

← Older revision		Revision as of 05:02, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Flynn, G C.]]		[[Category: Flynn, G C]]
	[[Category: Hu, W.]]		[[Category: Hu, W]]
	[[Category: Kurochkin, A V.]]		[[Category: Kurochkin, A V]]
	[[Category: Pang, Y.]]		[[Category: Pang, Y]]
	[[Category: Wang, H.]]		[[Category: Wang, H]]
	[[Category: Zuiderweg, E R.P.]]		[[Category: Zuiderweg, E R.P]]
	[[Category: Hsp70]]		[[Category: Hsp70]]
	[[Category: Molecular chaperone]]		[[Category: Molecular chaperone]]
	[[Category: Peptide binding]]		[[Category: Peptide binding]]
	[[Category: Protein folding]]		[[Category: Protein folding]]

OCA at 00:18, 30 September 2014

2014-09-30T00:18:49Z

← Older revision		Revision as of 00:18, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2bpr~~.~~png~~\|~~left~~\|~~200px~~]]		==NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES==
			<StructureSection load='2bpr' size='340' side='right' caption='[[2bpr]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BPR FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bpr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bpr RCSB], [http://www.ebi.ac.uk/pdbsum/2bpr PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/2bpr_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The solution structure of the 21 kDa substrate-binding domain of the Escherichia coli Hsp70-chaperone protein DnaK (DnaK 386-561) has been determined to a precision of 1.00 A (backbone of the beta-domain) from 1075 experimental restraints obtained from multinuclear, multidimensional NMR experiments. The domain is observed to bind to its own C-terminus and offers a preview of the interaction of this chaperone with other proteins. The bound protein region is tightly held at a single amino acid position (a leucyl residue) that is buried in a deep pocket lined with conserved hydrophobic residues. A second hydrophobic binding site was identified using paramagnetically labeled peptides. It is located in a region close to the N-terminus of the domain and may constitute the allosteric region that links substrate-binding affinity with nucleotide binding in the Hsp70 chaperones.

	~~{{STRUCTURE_2bpr\| PDB=2bpr \| SCENE= }}~~		NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.,Wang H, Kurochkin AV, Pang Y, Hu W, Flynn GC, Zuiderweg ER Biochemistry. 1998 Jun 2;37(22):7929-40. PMID:9609686<ref>PMID:9609686</ref>

	~~===NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK~~, ~~25 STRUCTURES===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_9609686}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2bpr]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:009609686<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Flynn, G C.]]		[[Category: Flynn, G C.]]

OCA: Protected "2bpr" [edit=sysop:move=sysop]

2013-01-06T09:43:00Z

Protected "2bpr" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:43, 6 January 2013
(No difference)

OCA at 09:42, 6 January 2013

2013-01-06T09:42:56Z

← Older revision		Revision as of 09:42, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2bpr.png\|left\|200px]]		[[Image:2bpr.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2bpr", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2bpr\| PDB=2bpr \| SCENE= }}		{{STRUCTURE_2bpr\| PDB=2bpr \| SCENE= }}

	===NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES===		===NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_9609686}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 9609686 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_9609686}}		{{ABSTRACT_PUBMED_9609686}}

	==About this Structure==		==About this Structure==
	~~2BPR~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA].		[[2bpr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPR OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~9609686~~</ref><references group="xtra"/>		<ref group="xtra">PMID:009609686</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Flynn, G C.]]		[[Category: Flynn, G C.]]
Line 35:		Line 23:
	[[Category: Peptide binding]]		[[Category: Peptide binding]]
	[[Category: Protein folding]]		[[Category: Protein folding]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:13:09 2009''~~