2br2 - Revision history

OCA at 13:53, 13 December 2023

2023-12-13T13:53:02Z

← Older revision		Revision as of 13:53, 13 December 2023
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	<StructureSection load='2br2' size='340' side='right'caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2br2' size='340' side='right'caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/~~'saccharolobus_solfataricus' 'saccharolobus~~ solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [https://pdbe.org/2br2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [https://www.ebi.ac.uk/pdbsum/2br2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2br2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [https://pdbe.org/2br2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [https://www.ebi.ac.uk/pdbsum/2br2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2br2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/~~ECX2_SULSO ECX2_SULSO~~]~~] Probably~~ involved in the ~~3'->5' degradation~~ of ~~a variety of RNA species (Potential)~~. [~~[https~~://~~www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'-~~>~~5' degradation of a variety of RNA species (Potential).~~		[https://www.uniprot.org/uniprot/RRP42_SACS2 RRP42_SACS2] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.[HAMAP-Rule:MF_00622]<ref>PMID:15951817</ref> <ref>PMID:20488184</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Saccharolobus solfataricus]]		[[Category: Saccharolobus solfataricus]]
	~~[[Category: Large Structures]]~~		[[Category: Conti E]]
	[[Category: Conti, E]]		[[Category: Fribourg S]]
	[[Category: Fribourg, S]]		[[Category: Lorentzen E]]
	[[Category: Lorentzen, E]]
	~~[[Category: Archaeal]]~~
	~~[[Category: Exoribonuclease]]~~
	~~[[Category: Exosome]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Phosphorolytic]]~~
	~~[[Category: Rna degradation]]~~
	~~[[Category: Rnase ph~~]]

OCA at 13:15, 24 November 2021

2021-11-24T13:15:53Z

← Older revision		Revision as of 13:15, 24 November 2021
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	<StructureSection load='2br2' size='340' side='right'caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2br2' size='340' side='right'caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [~~http~~://pdbe.org/2br2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2br2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2br2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [https://pdbe.org/2br2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [https://www.ebi.ac.uk/pdbsum/2br2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2br2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ECX2_SULSO ECX2_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential). [[~~http~~://www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential).		[[https://www.uniprot.org/uniprot/ECX2_SULSO ECX2_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential). [[https://www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:57, 19 February 2020

2020-02-19T07:57:00Z

← Older revision		Revision as of 07:57, 19 February 2020
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	==RNase PH core of the archaeal exosome==		==RNase PH core of the archaeal exosome==
	<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2br2' size='340' side='right'caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Exonuclease\|Exonuclease]]		*[[Exosome 3D structures\|Exosome 3D structures]]
	*[[Exosome\|Exosome]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Saccharolobus solfataricus]]		[[Category: Saccharolobus solfataricus]]
			[[Category: Large Structures]]
	[[Category: Conti, E]]		[[Category: Conti, E]]
	[[Category: Fribourg, S]]		[[Category: Fribourg, S]]

OCA at 06:17, 16 May 2018

2018-05-16T06:17:01Z

← Older revision		Revision as of 06:17, 16 May 2018
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	==~~RNASE~~ PH ~~CORE OF THE ARCHAEAL EXOSOME~~==
			==RNase PH core of the archaeal exosome==
	<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_solfataricus' 'saccharolobus solfataricus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://pdbe.org/2br2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://pdbe.org/2br2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2br2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2br2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2br2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2br2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Atcc 35091~~]]		[[Category: Saccharolobus solfataricus]]
	[[Category: Conti, E]]		[[Category: Conti, E]]
	[[Category: Fribourg, S]]		[[Category: Fribourg, S]]

OCA at 23:40, 11 September 2015

2015-09-11T23:40:50Z

← Older revision		Revision as of 23:40, 11 September 2015
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	<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://pdbe.org/2br2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2br2" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Exonuclease\|Exonuclease]]		*[[Exonuclease\|Exonuclease]]
			*[[Exosome\|Exosome]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Sulfolobus solfataricus~~]]		[[Category: Atcc 35091]]
	[[Category: Conti, E]]		[[Category: Conti, E]]
	[[Category: Fribourg, S]]		[[Category: Fribourg, S]]

OCA at 20:56, 25 December 2014

2014-12-25T20:56:58Z

← Older revision		Revision as of 20:56, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/ECX2_SULSO ECX2_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential). [[http://www.uniprot.org/uniprot/ECX1_SULSO ECX1_SULSO]] Probably involved in the 3'->5' degradation of a variety of RNA species (Potential).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Conti, E.]]		[[Category: Conti, E]]
	[[Category: Fribourg, S.]]		[[Category: Fribourg, S]]
	[[Category: Lorentzen, E.]]		[[Category: Lorentzen, E]]
	[[Category: Archaeal]]		[[Category: Archaeal]]
	[[Category: Exoribonuclease]]		[[Category: Exoribonuclease]]

OCA at 04:29, 29 September 2014

2014-09-29T04:29:15Z

← Older revision		Revision as of 04:29, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2br2~~.~~png~~\|~~left~~\|~~200px~~]]		==RNASE PH CORE OF THE ARCHAEAL EXOSOME==
			<StructureSection load='2br2' size='340' side='right' caption='[[2br2]], [[Resolution\|resolution]] 2.80Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BR2 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2br2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2br2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2br2 RCSB], [http://www.ebi.ac.uk/pdbsum/2br2 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2br2_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The exosome is a 3' --> 5' exoribonuclease complex involved in RNA processing. We report the crystal structure of the RNase PH core complex of the Sulfolobus solfataricus exosome determined at a resolution of 2.8 A. The structure reveals a hexameric ring-like arrangement of three Rrp41-Rrp42 heterodimers, where both subunits adopt the RNase PH fold common to phosphorolytic exoribonucleases. Structure-guided mutagenesis reveals that the activity of the complex resides within the active sites of the Rrp41 subunits, all three of which face the same side of the hexameric structure. The Rrp42 subunit is inactive but contributes to the structuring of the Rrp41 active site. The high sequence similarity of this archaeal exosome to eukaryotic exosomes and its high structural similarity to the bacterial mRNA-degrading PNPase support a common basis for RNA-degrading machineries in all three domains of life.

	~~{{STRUCTURE_2br2\| PDB=2br2 \| SCENE= }}~~		The archaeal exosome core is a hexameric ring structure with three catalytic subunits.,Lorentzen E, Walter P, Fribourg S, Evguenieva-Hackenberg E, Klug G, Conti E Nat Struct Mol Biol. 2005 Jul;12(7):575-81. Epub 2005 Jun 12. PMID:15951817<ref>PMID:15951817</ref>

	~~===RNASE PH CORE OF THE ARCHAEAL EXOSOME===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_15951817}}~~

	~~==About this Structure==~~
	~~[[2br2]] is~~ a ~~24 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=2BR2 OCA].~~

	==See Also==		==See Also==
	*[[Exonuclease\|Exonuclease]]		*[[Exonuclease\|Exonuclease]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:015951817<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Conti, E.]]		[[Category: Conti, E.]]

OCA at 21:32, 20 October 2012

2012-10-20T21:32:56Z

← Older revision		Revision as of 21:32, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2br2]] is a 24 chain structure ~~of [[Exonuclease]]~~ with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA].		[[2br2]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA].

	==See Also==		==See Also==

OCA: Protected "2br2" [edit=sysop:move=sysop]

2012-07-27T13:35:11Z

Protected "2br2" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:35, 27 July 2012
(No difference)

OCA at 13:35, 27 July 2012

2012-07-27T13:35:09Z

← Older revision		Revision as of 13:35, 27 July 2012
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	~~{{Seed}}~~
	[[Image:2br2.png\|left\|200px]]		[[Image:2br2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2br2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2br2\| PDB=2br2 \| SCENE= }}		{{STRUCTURE_2br2\| PDB=2br2 \| SCENE= }}

	===RNASE PH CORE OF THE ARCHAEAL EXOSOME===		===RNASE PH CORE OF THE ARCHAEAL EXOSOME===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_15951817}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 15951817 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_15951817}}		{{ABSTRACT_PUBMED_15951817}}

	==About this Structure==		==About this Structure==
	~~2BR2~~ is a 24 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA].		[[2br2]] is a 24 chain structure of [[Exonuclease]] with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BR2 OCA].

			==See Also==
			*[[Exonuclease\|Exonuclease]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~15951817~~</ref><references group="xtra"/>		<ref group="xtra">PMID:015951817</ref><references group="xtra"/>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
	[[Category: Conti, E.]]		[[Category: Conti, E.]]
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	[[Category: Rna degradation]]		[[Category: Rna degradation]]
	[[Category: Rnase ph]]		[[Category: Rnase ph]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:59:30 2009''~~