2brd - Revision history

OCA at 07:53, 30 October 2024

2024-10-30T07:53:11Z

← Older revision		Revision as of 07:53, 30 October 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2brd_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2brd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 11:23, 22 May 2024

2024-05-22T11:23:08Z

← Older revision		Revision as of 11:23, 22 May 2024
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	<StructureSection load='2brd' size='340' side='right'caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2brd' size='340' side='right'caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=~~RET~~:~~RETINAL~~'>~~RET~~</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution\|Resolution]] 3.5Å</td></tr>
	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~PCA~~:~~PYROGLUTAMIC+ACID~~'>~~PCA~~</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [https://pdbe.org/2brd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [https://www.ebi.ac.uk/pdbsum/2brd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2brd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [https://pdbe.org/2brd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [https://www.ebi.ac.uk/pdbsum/2brd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2brd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.		[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus halobius ruber klebahn 1919~~]]		[[Category: Halobacterium salinarum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Grigorieff, N]]		[[Category: Grigorieff N]]
	[[Category: Henderson, R]]		[[Category: Henderson R]]
	~~[[Category: Membrane protein]]~~
	~~[[Category: Photoreceptor]]~~
	~~[[Category: Proton pump]]~~
	~~[[Category: Retinal protein]]~~
	~~[[Category: Two-dimensional crystal~~]]

OCA at 13:16, 24 November 2021

2021-11-24T13:16:16Z

← Older revision		Revision as of 13:16, 24 November 2021
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	<StructureSection load='2brd' size='340' side='right'caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2brd' size='340' side='right'caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [~~http~~://pdbe.org/2brd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2brd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2brd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [https://pdbe.org/2brd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [https://www.ebi.ac.uk/pdbsum/2brd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2brd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.		[[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:04, 19 February 2020

2020-02-19T08:04:38Z

← Older revision		Revision as of 08:04, 19 February 2020
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE==		==CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE==
	<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2brd' size='340' side='right'caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
Line 31:		Line 31:

	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin 3D structures\|Bacteriorhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus halobius ruber klebahn 1919]]		[[Category: Bacillus halobius ruber klebahn 1919]]
			[[Category: Large Structures]]
	[[Category: Grigorieff, N]]		[[Category: Grigorieff, N]]
	[[Category: Henderson, R]]		[[Category: Henderson, R]]

OCA at 06:28, 16 May 2018

2018-05-16T06:28:31Z

← Older revision		Revision as of 06:28, 16 May 2018
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE==		==CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE==
	<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://pdbe.org/2brd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://pdbe.org/2brd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2brd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2brd_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2brd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:01, 10 February 2016

2016-02-10T03:01:53Z

← Older revision		Revision as of 03:01, 10 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2brd ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:44, 11 September 2015

2015-09-11T04:44:20Z

← Older revision		Revision as of 04:44, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Halobacterium_salinarum Halobacterium salinarum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://pdbe.org/2brd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 25:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2brd" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Halobacterium salinarum~~]]		[[Category: Bacillus halobius ruber klebahn 1919]]
	[[Category: Grigorieff, N]]		[[Category: Grigorieff, N]]
	[[Category: Henderson, R]]		[[Category: Henderson, R]]

OCA at 09:17, 8 January 2015

2015-01-08T09:17:22Z

← Older revision		Revision as of 09:17, 8 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Halobacterium salinarum]]		[[Category: Halobacterium salinarum]]
	[[Category: Grigorieff, N.]]		[[Category: Grigorieff, N]]
	[[Category: Henderson, R.]]		[[Category: Henderson, R]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Photoreceptor]]		[[Category: Photoreceptor]]

OCA at 02:21, 29 September 2014

2014-09-29T02:21:33Z

← Older revision		Revision as of 02:21, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2brd~~.~~png~~\|~~left~~\|~~200px~~]]		==CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE==
			<StructureSection load='2brd' size='340' side='right' caption='[[2brd]], [[Resolution\|resolution]] 3.50Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BRD FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPG:PHOSPHORIC+ACID+2,3-BIS-(3,7,11,15-TETRAMETHYL-HEXADECYLOXY)-PROPYL+ESTER+2-HYDROXO-3-PHOSPHONOOXY-PROPYL+ESTER'>DPG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene><br>
			<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2brd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2brd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2brd RCSB], [http://www.ebi.ac.uk/pdbsum/2brd PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2brd_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Using electron diffraction data corrected for diffuse scattering together with additional phase information from 30 new images of tilted specimens, an improved experimental density map has been calculated for bacteriorhodopsin. The atomic model has then been rebuilt into this new map with particular attention to the surface loops. All the residues from 7 to 227 as well as ten lipid molecules are now included, although a few amino acid residues in three of the six surface loops, about half of the lipid hydrophobic chains and all of the lipid head groups are disordered. The model has then been refined against the experimental diffraction amplitudes to an R-factor of 28% at 3.5 angstrom resolution with strict geometry (0.005 angstrom) bond length deviation) using the improvement of the "free" phase residual between calculated and experimental phases from images as an objective criterion of accuracy. For the refinement some new programs were developed to restrain the number of parameters, to be compatible with the limited resolution of our data. In the final refined model of the protein (2BRD), compared with earlier co-ordinates (1BRD), helix D has been moved towards the cytoplasm by almost 4 angstrom, and the overall accuracy of the co-ordinates of residues in the other six helices has been improved. As a result the positions of nearly all the important residues in bacteriorhodopsin are now well determined. In particular, the buried, protonated Asp115 is 7 angstrom from, and so not in contact with, the retinal and Met118 forms a cap on the pocket occupied by the beta-ionone ring. No clear density exists for the side-chain of Arg82, which forms a central part of the extracellular half-channel. The only arginine side-chain built into good density is that of Arg134 at the extracellular end of helix E, the others being disordered near one of the two surfaces. The interpretation of the end of helix F on the extracellular surface is now clearer; an extra loose helical turn has been built bringing the side-chain of Glu194 close to Arg134 to form a probable salt bridge. The model provides an improved framework for understanding the mechanism of the light-driven proton pumping. A number of cavities that could contain water molecules were found by searching the refined model, most of them above or below the Schiff base in the half-channels leading to the two surfaces. The ordered and disordered regions of the structure are described by the temperature factor distribution.

	~~{{STRUCTURE_2brd\| PDB=2brd \| SCENE= }}~~		Electron-crystallographic refinement of the structure of bacteriorhodopsin.,Grigorieff N, Ceska TA, Downing KH, Baldwin JM, Henderson R J Mol Biol. 1996 Jun 14;259(3):393-421. PMID:8676377<ref>PMID:8676377</ref>

	~~===CRYSTAL STRUCTURE OF BACTERIORHODOPSIN IN PURPLE MEMBRANE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_8676377}}~~

	~~==About this Structure==~~
	~~[[2brd]] is~~ a ~~1 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Halobacterium_salinarum Halobacterium salinarum]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=2BRD OCA].~~

	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin\|Bacteriorhodopsin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:008676377<~~/~~ref~~><~~ref group="xtra">PMID:009241769</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Halobacterium salinarum]]		[[Category: Halobacterium salinarum]]
	[[Category: Grigorieff, N.]]		[[Category: Grigorieff, N.]]

OCA at 16:05, 20 October 2012

2012-10-20T16:05:56Z

← Older revision		Revision as of 16:05, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2brd]] is a 1 chain structure ~~of [[Bacteriorhodopsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA].		[[2brd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRD OCA].

	==See Also==		==See Also==