2bs8 - Revision history

OCA at 13:54, 13 December 2023

2023-12-13T13:54:16Z

← Older revision		Revision as of 13:54, 13 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_B Escherichia coli B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_B Escherichia coli B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [https://pdbe.org/2bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [https://pdbe.org/2bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:12, 8 February 2023

2023-02-08T07:12:36Z

← Older revision		Revision as of 07:12, 8 February 2023
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	<StructureSection load='2bs8' size='340' side='right'caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bs8' size='340' side='right'caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Escherichia_coli_(strain_b)~~ Escherichia coli ~~(strain b)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_B Escherichia coli B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bs7\|2bs7]]</div></td></tr>~~
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [https://pdbe.org/2bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [https://pdbe.org/2bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.		[https://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Escherichia coli B]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert J]]
	[[Category: Buts, L]]		[[Category: Buts L]]
	[[Category: DeGreve, H]]		[[Category: DeGreve H]]
	[[Category: Lahmann, M]]		[[Category: Lahmann M]]
	[[Category: Loris, R]]		[[Category: Loris R]]
	[[Category: Oscarson, S]]		[[Category: Oscarson S]]
	[[Category: VanMolle, I]]		[[Category: VanMolle I]]
	[[Category: Wellens, A]]		[[Category: Wellens A]]
	[[Category: Wyns, L]]		[[Category: Wyns L]]
	~~[[Category: Fimbriae]]~~
	~~[[Category: Lectin]]~~
	~~[[Category: Protein-sugar complex]]~~
	~~[[Category: Sugar binding protein]]~~
	~~[[Category: Sugar-binding protein~~]]

OCA at 09:44, 5 May 2021

2021-05-05T09:44:37Z

← Older revision		Revision as of 09:44, 5 May 2021
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	<StructureSection load='2bs8' size='340' side='right'caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bs8' size='340' side='right'caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Escherichia_coli_(strain_b) Escherichia coli (strain b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_(strain_b) Escherichia coli (strain b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bs7\|2bs7]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [~~http~~://pdbe.org/2bs8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [https://pdbe.org/2bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.		[[https://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:52, 10 May 2019

2019-05-10T11:52:22Z

← Older revision		Revision as of 11:52, 10 May 2019
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	==Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine==		==Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine==
	<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bs8' size='340' side='right'caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_(strain_b) Escherichia coli (strain b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_(strain_b) Escherichia coli (strain b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Adhesin\|Adhesin]]		*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Buts, L]]		[[Category: Buts, L]]

OCA at 06:31, 16 May 2018

2018-05-16T06:31:07Z

← Older revision		Revision as of 06:31, 16 May 2018
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	==Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine==		==Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine==
	<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://pdbe.org/2bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://pdbe.org/2bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Protein-sugar complex]]		[[Category: Protein-sugar complex]]
			[[Category: Sugar binding protein]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]

OCA at 07:05, 10 September 2015

2015-09-10T07:05:09Z

← Older revision		Revision as of 07:05, 10 September 2015
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	<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_(strain_b) Escherichia coli (strain b)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://pdbe.org/2bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bs8" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Adhesin\|Adhesin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Bacillus coli migula 1895]]~~
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Buts, L]]		[[Category: Buts, L]]

OCA at 19:58, 24 December 2014

2014-12-24T19:58:40Z

← Older revision		Revision as of 19:58, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 05:25, 22 December 2014

2014-12-22T05:25:56Z

← Older revision		Revision as of 05:25, 22 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_2bs8\| PDB=2bs8 \| SCENE= }}~~		==Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine==
	===Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine===		<StructureSection load='2bs8' size='340' side='right' caption='[[2bs8]], [[Resolution\|resolution]] 2.25Å' scene=''>
	~~{{ABSTRACT_PUBMED_16041081}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS8 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bs7\|2bs7]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs8 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Since the introduction of structural genomics, the protein has been recognized as the most important variable in crystallization. Recent strategies to modify a protein to improve crystal quality have included rationally engineered point mutations, truncations, deletions and fusions. Five naturally occurring variants, differing in 1-18 amino acids, of the 177-residue lectin domain of the F17G fimbrial adhesin were expressed and purified in identical ways. For four out of the five variants crystals were obtained, mostly in non-isomorphous space groups, with diffraction limits ranging between 2.4 and 1.1 A resolution. A comparative analysis of the crystal-packing contacts revealed that the variable amino acids are often involved in lattice contacts and a single amino-acid substitution can suffice to radically change crystal packing. A statistical approach proved reliable to estimate the compatibilities of the variant sequences with the observed crystal forms. In conclusion, natural variation, universally present within prokaryotic species, is a valuable genetic resource that can be favourably employed to enhance the crystallization success rate with considerably less effort than other strategies.

	~~==Function==~~		Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.,Buts L, Wellens A, Van Molle I, Wyns L, Loris R, Lahmann M, Oscarson S, De Greve H, Bouckaert J Acta Crystallogr D Biol Crystallogr. 2005 Aug;61(Pt 8):1149-59. Epub 2005, Jul 20. PMID:16041081<ref>PMID:16041081</ref>
	~~[[http://www~~.~~uniprot~~.~~org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N~~-~~acetylglucosamine-containing receptors in the host intestinal microvilli~~, ~~leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes~~.

	~~==About this Structure==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[2bs8]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA].~~		</div>
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:016041081</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Bouckaert, J.]]		[[Category: Bouckaert, J]]
	[[Category: Buts, L.]]		[[Category: Buts, L]]
	[[Category: DeGreve, H.]]		[[Category: DeGreve, H]]
	[[Category: Lahmann, M.]]		[[Category: Lahmann, M]]
	[[Category: Loris, R.]]		[[Category: Loris, R]]
	[[Category: Oscarson, S.]]		[[Category: Oscarson, S]]
	[[Category: VanMolle, I.]]		[[Category: VanMolle, I]]
	[[Category: Wellens, A.]]		[[Category: Wellens, A]]
	[[Category: Wyns, L.]]		[[Category: Wyns, L]]
	[[Category: Fimbriae]]		[[Category: Fimbriae]]
	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Protein-sugar complex]]		[[Category: Protein-sugar complex]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]

OCA at 06:16, 4 December 2013

2013-12-04T06:16:53Z

← Older revision		Revision as of 06:16, 4 December 2013
Line 1:		Line 1:
	~~[[Image:2bs8.png\|left\|200px]]~~

	{{STRUCTURE_2bs8\| PDB=2bs8 \| SCENE= }}		{{STRUCTURE_2bs8\| PDB=2bs8 \| SCENE= }}
			===Crystal structure of F17b-G in complex with N-acetyl-D-glucosamine===
			{{ABSTRACT_PUBMED_16041081}}

	===~~CRYSTAL STRUCTURE OF F17B-G IN COMPLEX WITH~~ N-~~ACETYL~~-~~D-GLUCOSAMINE===~~		==Function==
			[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	~~{{ABSTRACT_PUBMED_16041081}}~~

	==About this Structure==		==About this Structure==
	[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA].		[[2bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS8 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:016041081</ref><references group="xtra"/>		<ref group="xtra">PMID:016041081</ref><references group="xtra"/><references/>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Bouckaert, J.]]		[[Category: Bouckaert, J.]]
	[[Category: Buts, L.]]		[[Category: Buts, L.]]
	[[Category: ~~Greve~~, H De.]]		[[Category: DeGreve, H.]]
	[[Category: Lahmann, M.]]		[[Category: Lahmann, M.]]
	[[Category: Loris, R.]]		[[Category: Loris, R.]]
	~~[[Category: Molle, I Van.]]~~
	[[Category: Oscarson, S.]]		[[Category: Oscarson, S.]]
			[[Category: VanMolle, I.]]
	[[Category: Wellens, A.]]		[[Category: Wellens, A.]]
	[[Category: Wyns, L.]]		[[Category: Wyns, L.]]
	~~[[Category: Adhesin]]~~
	[[Category: Fimbriae]]		[[Category: Fimbriae]]
	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Protein-sugar complex]]		[[Category: Protein-sugar complex]]
			[[Category: Sugar-binding protein]]

OCA: Protected "2bs8" [edit=sysop:move=sysop]

2012-08-14T15:39:25Z

Protected "2bs8" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:39, 14 August 2012
(No difference)