2bwe - Revision history

OCA at 13:57, 13 December 2023

2023-12-13T13:57:02Z

← Older revision		Revision as of 13:57, 13 December 2023
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	<StructureSection load='2bwe' size='340' side='right'caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2bwe' size='340' side='right'caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1wr1\|1wr1]]~~, [[~~2bwb~~\|~~2bwb~~]]~~, [[2bwf\|2bwf]]</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [https://pdbe.org/2bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [https://www.ebi.ac.uk/pdbsum/2bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [https://pdbe.org/2bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [https://www.ebi.ac.uk/pdbsum/2bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwe ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/DSK2_YEAST DSK2_YEAST] Involved, with RAD23 in spindle pole body duplication. Involved in the ubiquitin-proteasome proteolytic pathway.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 18824]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Brown~~, N R~~]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Endicott~~, J A~~]]		[[Category: Brown NR]]
	[[Category: Fonso, L]]		[[Category: Endicott JA]]
	[[Category: Hasan, N]]		[[Category: Fonso L]]
	[[Category: Johnson~~, L N~~]]		[[Category: Hasan N]]
	[[Category: Lowe~~, E D~~]]		[[Category: Johnson LN]]
	[[Category: Noble~~, M E.M~~]]		[[Category: Lowe ED]]
	[[Category: Trempe, J F]]		[[Category: Noble MEM]]
	~~[[Category: Protein/protein interaction]]~~		[[Category: Trempe J-F]]
	~~[[Category: Signaling protein]]~~
	~~[[Category: Ubiquitin]]~~
	~~[[Category: Ubiquitin-like protein~~]]

OCA at 07:11, 24 February 2021

2021-02-24T07:11:08Z

← Older revision		Revision as of 07:11, 24 February 2021
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	<StructureSection load='2bwe' size='340' side='right'caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2bwe' size='340' side='right'caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [~~http~~://pdbe.org/2bwe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2bwe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [https://pdbe.org/2bwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [https://www.ebi.ac.uk/pdbsum/2bwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:42, 21 May 2019

2019-05-21T07:42:57Z

← Older revision		Revision as of 07:42, 21 May 2019
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	==The crystal structure of the complex between the UBA and UBL domains of Dsk2==		==The crystal structure of the complex between the UBA and UBL domains of Dsk2==
	<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2bwe' size='340' side='right'caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
			[[Category: Large Structures]]
	[[Category: Brown, N R]]		[[Category: Brown, N R]]
	[[Category: Endicott, J A]]		[[Category: Endicott, J A]]

OCA at 07:36, 24 October 2018

2018-10-24T07:36:21Z

← Older revision		Revision as of 07:36, 24 October 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/2bwe_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/2bwe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:25, 18 January 2017

2017-01-18T17:25:59Z

← Older revision		Revision as of 17:25, 18 January 2017
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	==The crystal structure of the complex between the UBA and UBL domains of Dsk2==		==The crystal structure of the complex between the UBA and UBL domains of Dsk2==
	<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://pdbe.org/2bwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2bwe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bwe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2bwe" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:45, 15 April 2015

2015-04-15T06:45:46Z

← Older revision		Revision as of 06:45, 15 April 2015
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	[[Category: Fonso, L]]		[[Category: Fonso, L]]
	[[Category: Hasan, N]]		[[Category: Hasan, N]]
	[[Category: L N~~., Johnson~~]]		[[Category: Johnson, L N]]
	[[Category: Lowe, E D]]		[[Category: Lowe, E D]]
	[[Category: Noble, M E.M]]		[[Category: Noble, M E.M]]

OCA at 07:29, 1 April 2015

2015-04-01T07:29:30Z

← Older revision		Revision as of 07:29, 1 April 2015
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	==~~THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE~~ UBA ~~AND~~ UBL ~~DOMAINS OF DSK2~~==		==The crystal structure of the complex between the UBA and UBL domains of Dsk2==
	<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Saccharomyces cerevisiae~~]]		[[Category: Atcc 18824]]
	[[Category: Brown, N R]]		[[Category: Brown, N R]]
	[[Category: Endicott, J A]]		[[Category: Endicott, J A]]
	[[Category: Fonso, L]]		[[Category: Fonso, L]]
	[[Category: Hasan, N]]		[[Category: Hasan, N]]
	[[Category: ~~Johnson,~~ L N]]		[[Category: L N., Johnson]]
	[[Category: Lowe, E D]]		[[Category: Lowe, E D]]
	[[Category: Noble, M E.M]]		[[Category: Noble, M E.M]]
	[[Category: Trempe, J-F]]		[[Category: Trempe, J F]]
	[[Category: Protein/protein interaction]]		[[Category: Protein/protein interaction]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Ubiquitin]]		[[Category: Ubiquitin]]
	[[Category: Ubiquitin-like protein]]		[[Category: Ubiquitin-like protein]]

OCA at 16:20, 15 January 2015

2015-01-15T16:20:47Z

← Older revision		Revision as of 16:20, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Brown, N R.]]		[[Category: Brown, N R]]
	[[Category: Endicott, J A.]]		[[Category: Endicott, J A]]
	[[Category: Fonso, L.]]		[[Category: Fonso, L]]
	[[Category: Hasan, N.]]		[[Category: Hasan, N]]
	[[Category: Johnson, L N.]]		[[Category: Johnson, L N]]
	[[Category: Lowe, E D.]]		[[Category: Lowe, E D]]
	[[Category: Noble, M E.M.]]		[[Category: Noble, M E.M]]
	[[Category: Trempe, J-F.]]		[[Category: Trempe, J-F]]
	[[Category: Protein/protein interaction]]		[[Category: Protein/protein interaction]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Ubiquitin]]		[[Category: Ubiquitin]]
	[[Category: Ubiquitin-like protein]]		[[Category: Ubiquitin-like protein]]

OCA at 01:41, 30 September 2014

2014-09-30T01:41:06Z

← Older revision		Revision as of 01:41, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2bwe~~.~~png~~\|~~left~~\|~~200px~~]]		==THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE UBA AND UBL DOMAINS OF DSK2==
			<StructureSection load='2bwe' size='340' side='right' caption='[[2bwe]], [[Resolution\|resolution]] 3.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2bwe]] is a 21 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BWE FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1wr1\|1wr1]], [[2bwb\|2bwb]], [[2bwf\|2bwf]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bwe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bwe RCSB], [http://www.ebi.ac.uk/pdbsum/2bwe PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/2bwe_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The yeast proteins Dsk2 and Rad23 belong to a family of proteins that contain an N-terminal ubiquitin-like domain (UBL) and a C-terminal ubiquitin-associated domain (UBA). Both Dsk2 and Rad23 function as adaptors to target ubiquitin-labelled proteins to the proteasome through recognition of polyubiquitin (four or more K48-linked ubiquitins) by their UBA domains and to the yeast proteasomal subunit Rpn1 by their UBL domains. The crystal structures of the Dsk2 UBL domain, the Dsk2 UBA domain and the Dsk2 UBA-UBL complex are reported. In the crystal, the Dsk2 UBA domains associate through electrostatic interactions to form ninefold helical ribbons that leave the ubiquitin-binding surface exposed. The UBA-UBL complex explains the reduced affinity of the UBA domain for UBL compared with ubiquitin and has implications for the regulation of Dsk2 adaptor function during ubiquitin-mediated proteasomal targeting. A model is discussed in which two or more Dsk2 UBA molecules may selectively bind to K48-linked polyubiquitin.

	~~{{STRUCTURE_2bwe\| PDB=2bwe \| SCENE= }}~~		Structures of the Dsk2 UBL and UBA domains and their complex.,Lowe ED, Hasan N, Trempe JF, Fonso L, Noble ME, Endicott JA, Johnson LN, Brown NR Acta Crystallogr D Biol Crystallogr. 2006 Feb;62(Pt 2):177-88. Epub 2006, Jan 18. PMID:16421449<ref>PMID:16421449</ref>

	~~===THE CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE UBA AND UBL DOMAINS OF DSK2===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16421449}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2bwe]] is~~ a ~~21 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2BWE OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016421449<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Brown, N R.]]		[[Category: Brown, N R.]]

OCA: Protected "2bwe" [edit=sysop:move=sysop]

2013-01-06T10:55:48Z

Protected "2bwe" [edit=sysop:move=sysop]

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