2ca0 - Revision history

OCA at 17:19, 8 September 2026

2026-09-08T17:19:56Z

← Older revision		Revision as of 17:19, 8 September 2026
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca0_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 14:11, 13 December 2023

2023-12-13T14:11:01Z

← Older revision		Revision as of 14:11, 13 December 2023
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	<StructureSection load='2ca0' size='340' side='right'caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='2ca0' size='340' side='right'caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_4.1526 As 4.1526~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.85Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [https://pdbe.org/2ca0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [https://pdbe.org/2ca0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca0 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/PIKC_STRVZ PIKC_STRVZ] Catalyzes the hydroxylation of narbomycin to give rise to pikromycin, and of 10-deoxymethymycin (YC-17) to give rise to methymycin and neomethymycin during macrolide antibiotic biosynthesis. In addition, produces low amounts of neopicromycin, novapikromycin and novamethymycin. Requires the participation of a ferredoxin and a ferredoxin reductase for the transfer of electrons from NADPH to the monooxygenase.<ref>PMID:16825192</ref> <ref>PMID:19124459</ref> <ref>PMID:19833867</ref> <ref>PMID:24627965</ref> <ref>PMID:9778370</ref> <ref>PMID:9831532</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]		*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	*[[Cytochrome P450 hydroxylase 3D structures\|Cytochrome P450 hydroxylase 3D structures]]		*[[Cytochrome P450 hydroxylase 3D structures\|Cytochrome P450 hydroxylase 3D structures]]
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: As 4 1526]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Kim, Y~~]]		[[Category: Streptomyces venezuelae]]
	[[Category: ~~Podust, L M~~]]		[[Category: Kim Y]]
	[[Category: ~~Sherman, D H~~]]		[[Category: Podust LM]]
	[[Category: ~~Waterman, M R~~]]		[[Category: Sherman DH]]
	[[Category: ~~Yermalitskaya, L I~~]]		[[Category: Waterman MR]]
	[[Category: ~~Antibiotic biosynthesis]]~~		[[Category: Yermalitskaya LI]]
	~~[[Category: Cytochrome p450]]~~
	~~[[Category: Heme]]~~
	~~[[Category: Iron]]~~
	~~[[Category: Macrolide monooxygenase]]~~
	~~[[Category: Metal-binding]]~~
	~~[[Category: Oxidoreductase]]~~
	~~[[Category: Pikc]]~~
	~~[[Category: Yc-17~~]]

OCA at 06:51, 1 December 2021

2021-12-01T06:51:32Z

← Older revision		Revision as of 06:51, 1 December 2021
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	<StructureSection load='2ca0' size='340' side='right'caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='2ca0' size='340' side='right'caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_4.1526 As 4.1526]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1526 As 4.1526]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [~~http~~://pdbe.org/2ca0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ca0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [https://pdbe.org/2ca0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:51, 26 February 2020

2020-02-26T10:51:12Z

← Older revision		Revision as of 10:51, 26 February 2020
Line 1:		Line 1:

	==Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)==		==Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)==
	<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='2ca0' size='340' side='right'caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1526 As 4.1526]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1526 As 4.1526]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	*[[Cytochrome P450 hydroxylase\|Cytochrome P450 hydroxylase]]		*[[Cytochrome P450 hydroxylase 3D structures\|Cytochrome P450 hydroxylase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: As 4 1526]]		[[Category: As 4 1526]]
			[[Category: Large Structures]]
	[[Category: Kim, Y]]		[[Category: Kim, Y]]
	[[Category: Podust, L M]]		[[Category: Podust, L M]]

OCA at 08:08, 23 May 2018

2018-05-23T08:08:24Z

← Older revision		Revision as of 08:08, 23 May 2018
Line 1:		Line 1:
	==~~CRYSTAL STRUCTURE OF~~ YC-17-~~BOUND CYTOCHROME~~ P450 ~~PIKC~~ (CYP107L1)==
			==Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)==
	<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://pdbe.org/2ca0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://pdbe.org/2ca0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca0_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 20:		Line 21:
	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450\|Cytochrome P450]]
			*[[Cytochrome P450 hydroxylase\|Cytochrome P450 hydroxylase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:31, 7 February 2016

2016-02-07T10:31:20Z

← Older revision		Revision as of 10:31, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ca0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 00:40, 10 September 2015

2015-09-10T00:40:39Z

← Older revision		Revision as of 00:40, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>		<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_venezuelae Streptomyces venezuelae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1526 As 4.1526]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://pdbe.org/2ca0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Streptomyces venezuelae~~]]		[[Category: As 4 1526]]
	[[Category: Kim, Y]]		[[Category: Kim, Y]]
	[[Category: Podust, L M]]		[[Category: Podust, L M]]

OCA at 16:19, 15 January 2015

2015-01-15T16:19:32Z

← Older revision		Revision as of 16:19, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Streptomyces venezuelae]]		[[Category: Streptomyces venezuelae]]
	[[Category: Kim, Y.]]		[[Category: Kim, Y]]
	[[Category: Podust, L M.]]		[[Category: Podust, L M]]
	[[Category: Sherman, D H.]]		[[Category: Sherman, D H]]
	[[Category: Waterman, M R.]]		[[Category: Waterman, M R]]
	[[Category: Yermalitskaya, L I.]]		[[Category: Yermalitskaya, L I]]
	[[Category: Antibiotic biosynthesis]]		[[Category: Antibiotic biosynthesis]]
	[[Category: Cytochrome p450]]		[[Category: Cytochrome p450]]

OCA at 04:32, 29 September 2014

2014-09-29T04:32:00Z

← Older revision		Revision as of 04:32, 29 September 2014
Line 1:		Line 1:
	~~[[Image:2ca0.png\|left\|200px]]~~		==CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC (CYP107L1)==
			<StructureSection load='2ca0' size='340' side='right' caption='[[2ca0]], [[Resolution\|resolution]] 2.85Å' scene=''>
	~~{{STRUCTURE_2ca0\| PDB=2ca0 \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA0 FirstGlance]. <br>
	===CRYSTAL STRUCTURE OF YC-17-BOUND CYTOCHROME P450 PIKC (CYP107L1)===		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PXI:4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE'>PXI</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bvj\|2bvj]], [[2c6h\|2c6h]], [[2c7x\|2c7x]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca0 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca0 PDBsum]</span></td></tr>
	==~~About this Structure~~==		<table>
	[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA].		== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca0_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450\|Cytochrome P450]]
			__TOC__
			</StructureSection>
	[[Category: Streptomyces venezuelae]]		[[Category: Streptomyces venezuelae]]
	[[Category: Kim, Y.]]		[[Category: Kim, Y.]]

OCA at 06:22, 20 October 2012

2012-10-20T06:22:29Z

← Older revision		Revision as of 06:22, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
	[[2ca0]] is a 2 chain structure ~~of [[Cytochrome P450]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA].		[[2ca0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_venezuelae Streptomyces venezuelae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA0 OCA].

	==See Also==		==See Also==