2ca1 - Revision history

OCA at 09:23, 9 May 2024

2024-05-09T09:23:45Z

← Older revision		Revision as of 09:23, 9 May 2024
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	<StructureSection load='2ca1' size='340' side='right'caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2ca1' size='340' side='right'caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Avian_infectious_bronchitis_virus Avian infectious~~ bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [https://pdbe.org/2ca1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca1 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [https://pdbe.org/2ca1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca1 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/NCAP_IBVB NCAP_IBVB] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.[HAMAP-Rule:MF_04097]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Avian infectious~~ bronchitis virus]]		[[Category: Infectious bronchitis virus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bowman~~, B R~~]]		[[Category: Bowman BR]]
	[[Category: Collison~~, E W~~]]		[[Category: Collison EW]]
	[[Category: Fan, H]]		[[Category: Fan H]]
	[[Category: Jayaram, H]]		[[Category: Jayaram H]]
	[[Category: Jayaram, J]]		[[Category: Jayaram J]]
	[[Category: Lescar, J]]		[[Category: Lescar J]]
	[[Category: Ooi, A]]		[[Category: Ooi A]]
	[[Category: Prasad~~, B V.V]]~~		[[Category: Prasad BVV]]
	~~[[Category: Nucleocapsid protein]]~~
	~~[[Category: Viral nucleoprotein]]~~
	~~[[Category: Viral protein~~]]

OCA at 06:51, 1 December 2021

2021-12-01T06:51:33Z

← Older revision		Revision as of 06:51, 1 December 2021
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	<StructureSection load='2ca1' size='340' side='right'caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2ca1' size='340' side='right'caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [~~http~~://pdbe.org/2ca1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ca1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca1 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [https://pdbe.org/2ca1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:57, 26 February 2020

2020-02-26T10:57:15Z

← Older revision		Revision as of 10:57, 26 February 2020
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	==Crystal structure of the IBV coronavirus nucleocapsid==		==Crystal structure of the IBV coronavirus nucleocapsid==
	<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2ca1' size='340' side='right'caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Nucleoprotein\|Nucleoprotein]]		*[[Nucleoprotein 3D structures\|Nucleoprotein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Avian infectious bronchitis virus]]		[[Category: Avian infectious bronchitis virus]]
			[[Category: Large Structures]]
	[[Category: Bowman, B R]]		[[Category: Bowman, B R]]
	[[Category: Collison, E W]]		[[Category: Collison, E W]]

OCA at 08:18, 23 May 2018

2018-05-23T08:18:31Z

← Older revision		Revision as of 08:18, 23 May 2018
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	==~~CRYSTAL STRUCTURE OF THE~~ IBV ~~CORONAVIRUS NUCLEOCAPSID~~==
			==Crystal structure of the IBV coronavirus nucleocapsid==
	<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://pdbe.org/2ca1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://pdbe.org/2ca1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca1 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca1_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca1_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:48, 9 February 2016

2016-02-09T07:48:45Z

← Older revision		Revision as of 07:48, 9 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ca1 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:07, 10 September 2015

2015-09-10T20:07:23Z

← Older revision		Revision as of 20:07, 10 September 2015
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	<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Infectious_bronchitis_virus Infectious~~ bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_infectious_bronchitis_virus Avian infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://pdbe.org/2ca1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ca1" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Infectious~~ bronchitis virus]]		[[Category: Avian infectious bronchitis virus]]
	[[Category: Bowman, B R]]		[[Category: Bowman, B R]]
	[[Category: Collison, E W]]		[[Category: Collison, E W]]

OCA at 17:56, 15 January 2015

2015-01-15T17:56:37Z

← Older revision		Revision as of 17:56, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Infectious bronchitis virus]]		[[Category: Infectious bronchitis virus]]
	[[Category: Bowman, B R.]]		[[Category: Bowman, B R]]
	[[Category: Collison, E W.]]		[[Category: Collison, E W]]
	[[Category: Fan, H.]]		[[Category: Fan, H]]
	[[Category: Jayaram, H.]]		[[Category: Jayaram, H]]
	[[Category: Jayaram, J.]]		[[Category: Jayaram, J]]
	[[Category: Lescar, J.]]		[[Category: Lescar, J]]
	[[Category: Ooi, A.]]		[[Category: Ooi, A]]
	[[Category: Prasad, B V.V.]]		[[Category: Prasad, B V.V]]
	[[Category: Nucleocapsid protein]]		[[Category: Nucleocapsid protein]]
	[[Category: Viral nucleoprotein]]		[[Category: Viral nucleoprotein]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 05:08, 29 September 2014

2014-09-29T05:08:56Z

← Older revision		Revision as of 05:08, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2ca1~~.~~png~~\|~~left~~\|~~200px~~]]		==CRYSTAL STRUCTURE OF THE IBV CORONAVIRUS NUCLEOCAPSID==
			<StructureSection load='2ca1' size='340' side='right' caption='[[2ca1]], [[Resolution\|resolution]] 2.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA1 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca1 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca1_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Coronaviruses cause a variety of respiratory and enteric diseases in animals and humans including severe acute respiratory syndrome. In these enveloped viruses, the filamentous nucleocapsid is formed by the association of nucleocapsid (N) protein with single-stranded viral RNA. The N protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. We describe the structure of the two proteolytically resistant domains of the N protein from infectious bronchitis virus (IBV), a prototype coronavirus. These domains are located at its N- and C-terminal ends (NTD and CTD, respectively). The NTD of the IBV Gray strain at 1.3-A resolution exhibits a U-shaped structure, with two arms rich in basic residues, providing a module for specific interaction with RNA. The CTD forms a tightly intertwined dimer with an intermolecular four-stranded central beta-sheet platform flanked by alpha helices, indicating that the basic building block for coronavirus nucleocapsid formation is a dimeric assembly of N protein. The variety of quaternary arrangements of the NTD and CTD revealed by the analysis of the different crystal forms delineates possible interfaces that could be used for the formation of a flexible filamentous ribonucleocapsid. The striking similarity between the dimeric structure of CTD and the nucleocapsid-forming domain of a distantly related arterivirus indicates a conserved mechanism of nucleocapsid formation for these two viral families.

	~~{{STRUCTURE_2ca1\| PDB=2ca1 \| SCENE= }}~~		X-ray structures of the N- and C-terminal domains of a coronavirus nucleocapsid protein: implications for nucleocapsid formation.,Jayaram H, Fan H, Bowman BR, Ooi A, Jayaram J, Collisson EW, Lescar J, Prasad BV J Virol. 2006 Jul;80(13):6612-20. PMID:16775348<ref>PMID:16775348</ref>

	~~===CRYSTAL STRUCTURE OF THE IBV CORONAVIRUS NUCLEOCAPSID===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16775348}}~~

	~~==About this Structure==~~
	~~[[2ca1]] is~~ a ~~2 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=2CA1 OCA].~~

	==See Also==		==See Also==
	*[[Nucleoprotein\|Nucleoprotein]]		*[[Nucleoprotein\|Nucleoprotein]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:016775348<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Infectious bronchitis virus]]		[[Category: Infectious bronchitis virus]]
	[[Category: Bowman, B R.]]		[[Category: Bowman, B R.]]

OCA at 13:10, 20 October 2012

2012-10-20T13:10:27Z

← Older revision		Revision as of 13:10, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2ca1]] is a 2 chain structure ~~of [[Nucleoprotein]]~~ with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA].		[[2ca1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Infectious_bronchitis_virus Infectious bronchitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA1 OCA].

	==See Also==		==See Also==

OCA: Protected "2ca1" [edit=sysop:move=sysop]

2012-07-26T11:07:36Z

Protected "2ca1" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:07, 26 July 2012
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