2ca6 - Revision history

OCA at 09:23, 9 May 2024

2024-05-09T09:23:46Z

← Older revision		Revision as of 09:23, 9 May 2024
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	<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Cbs_356 Cbs 356~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [https://pdbe.org/2ca6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [https://pdbe.org/2ca6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO]] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.		[https://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Cbs 356]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Hillig, R C~~]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: ~~Renault, L~~]]		[[Category: Hillig RC]]
	[[Category: ~~Gap]]~~		[[Category: Renault L]]
	~~[[Category: Gtpase activation]]~~
	~~[[Category: Gtpase-activating protein]]~~
	~~[[Category: Hemihedral twinning]]~~
	~~[[Category: Leucine-rich repeat protein]]~~
	~~[[Category: Lrr]]~~
	~~[[Category: Merohedral twinning]]~~
	~~[[Category: Merohedry]]~~
	~~[[Category: Nuclear transport]]~~
	~~[[Category: Rangap]]~~
	~~[[Category: Rna1p]]~~
	~~[[Category: Signaling activator]]~~
	~~[[Category: Signaling protein]]~~
	~~[[Category: Signaling regulator~~]]

OCA at 09:46, 5 May 2021

2021-05-05T09:46:27Z

← Older revision		Revision as of 09:46, 5 May 2021
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	<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [~~http~~://pdbe.org/2ca6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [https://pdbe.org/2ca6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO]] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.		[[https://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO]] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:14, 24 July 2019

2019-07-24T07:14:51Z

← Older revision		Revision as of 07:14, 24 July 2019
Line 1:		Line 1:

	==MIRAS structure determination from hemihedrally twinned crystals==		==MIRAS structure determination from hemihedrally twinned crystals==
	<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2ca6' size='340' side='right'caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Cbs 356]]		[[Category: Cbs 356]]
			[[Category: Large Structures]]
	[[Category: Hillig, R C]]		[[Category: Hillig, R C]]
	[[Category: Renault, L]]		[[Category: Renault, L]]

OCA at 08:47, 23 May 2018

2018-05-23T08:47:22Z

← Older revision		Revision as of 08:47, 23 May 2018
Line 1:		Line 1:
	==MIRAS ~~STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS~~==
			==MIRAS structure determination from hemihedrally twinned crystals==
	<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://pdbe.org/2ca6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://pdbe.org/2ca6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca6_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ca6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:24, 11 September 2015

2015-09-11T21:24:55Z

← Older revision		Revision as of 21:24, 11 September 2015
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	<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe Schizosaccharomyces pombe~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://pdbe.org/2ca6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ca6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Schizosaccharomyces pombe~~]]		[[Category: Cbs 356]]
	[[Category: Hillig, R C]]		[[Category: Hillig, R C]]
	[[Category: Renault, L]]		[[Category: Renault, L]]

OCA at 19:57, 25 December 2014

2014-12-25T19:57:10Z

← Older revision		Revision as of 19:57, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/RNA1_SCHPO RNA1_SCHPO]] GTPase activator for the nuclear Ras-related regulatory protein spi1 (Ran), converting it to the putatively inactive GDP-bound state.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Hillig, R C.]]		[[Category: Hillig, R C]]
	[[Category: Renault, L.]]		[[Category: Renault, L]]
	[[Category: Gap]]		[[Category: Gap]]
	[[Category: Gtpase activation]]		[[Category: Gtpase activation]]

OCA at 01:27, 30 September 2014

2014-09-30T01:27:39Z

← Older revision		Revision as of 01:27, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2ca6~~.~~png~~\|~~left~~\|~~200px~~]]		==MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS==
			<StructureSection load='2ca6' size='340' side='right' caption='[[2ca6]], [[Resolution\|resolution]] 2.20Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA6 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k5d\|1k5d]], [[1k5g\|1k5g]], [[1yrg\|1yrg]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca6 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca6 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca6_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The structure of Rna1p was originally solved to 2.7 A resolution by MIRAS from crystals with partial hemihedral twinning in space group I4(1) [Hillig et al. (1999), Mol. Cell, 3, 781-791] by finding a low-twinned native crystal (twin fraction alpha=0.06) and after twin correction of all data sets. Rna1p crystals have now been used to examine how far twinning and twin correction affect MIR phasing with a higher resolution but highly twinned native data set. Even high hemihedral twinning [alphanative=0.39, alphaderivative=0.24] would not have hindered heavy-atom site identification of strong derivatives using difference Patterson maps. However, a weaker derivative could have been missed and refinement would have stalled at high R values had twinning not been identified and accounted for. Twin correction improved both site identification, experimental phasing statistics and MIR map quality. Different strategies were tested for refinement against twinned data. Using uncorrected twinned data and TWIN-CNS, Rna1p has now been refined to 2.2 A resolution (final twinned R and Rfree were 0.165 and 0.218, respectively). The increased resolution enabled release of the NCS restraints and allowed new conclusions to be drawn on the flexibility of the two molecules in the asymmetric unit. In the case of Rna1p, twinned crystal growth was possible owing to the presence of a twofold NCS axis almost parallel to the twin operator.

	~~{{STRUCTURE_2ca6\| PDB=2ca6 \| SCENE= }}~~		Detecting and overcoming hemihedral twinning during the MIR structure determination of Rna1p.,Hillig RC, Renault L Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):750-65. Epub 2006, Jun 20. PMID:16790931<ref>PMID:16790931</ref>

	~~===MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16790931}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2ca6]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016790931<~~/~~ref~~><~~ref group="xtra">PMID:010394366</ref><ref group="xtra">PMID:011832950</ref><references group="xtra"~~/>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Hillig, R C.]]		[[Category: Hillig, R C.]]

OCA at 12:37, 23 January 2013

2013-01-23T12:37:24Z

← Older revision		Revision as of 12:37, 23 January 2013
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	[[Image:2ca6.png\|left\|200px]]		[[Image:2ca6.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2ca6", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2ca6\| PDB=2ca6 \| SCENE= }}		{{STRUCTURE_2ca6\| PDB=2ca6 \| SCENE= }}

	===MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS===		===MIRAS STRUCTURE DETERMINATION FROM HEMIHEDRALLY TWINNED CRYSTALS===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16790931}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16790931 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_16790931}}		{{ABSTRACT_PUBMED_16790931}}

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	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16790931~~</ref><ref group="xtra">PMID:~~10394366~~</ref><ref group="xtra">PMID:~~11832950~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016790931</ref><ref group="xtra">PMID:010394366</ref><ref group="xtra">PMID:011832950</ref><references group="xtra"/>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Hillig, R C.]]		[[Category: Hillig, R C.]]

OCA: Protected "2ca6" [edit=sysop:move=sysop]

2011-03-14T21:12:57Z

Protected "2ca6" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:12, 14 March 2011
(No difference)

OCA at 21:12, 14 March 2011

2011-03-14T21:12:54Z

← Older revision		Revision as of 21:12, 14 March 2011
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	~~{{Seed}}~~
	[[Image:2ca6.png\|left\|200px]]		[[Image:2ca6.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
	~~2CA6~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA].		[[2ca6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA6 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:16790931</ref><references group="xtra"/>		<ref group="xtra">PMID:16790931</ref><ref group="xtra">PMID:10394366</ref><ref group="xtra">PMID:11832950</ref><references group="xtra"/>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Hillig, R C.]]		[[Category: Hillig, R C.]]
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	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Signaling regulator]]		[[Category: Signaling regulator]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:23:51 2009''~~