2cdp - Revision history

OCA at 14:14, 13 December 2023

2023-12-13T14:14:16Z

← Older revision		Revision as of 14:14, 13 December 2023
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	<StructureSection load='2cdp' size='340' side='right'caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='2cdp' size='340' side='right'caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Microbulbifer_degradans_2~~-40 ~~Microbulbifer~~ degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharophagus_degradans_2-40 Saccharophagus degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:~~CALCIUM+ION~~'>CA</scene>, <scene name='pdbligand=CL:~~CHLORIDE~~+ION'>CL</scene>, <scene name='pdbligand=~~EDO~~:~~1,2-ETHANEDIOL~~'>~~EDO~~</scene>, <scene name='pdbligand=~~AAL~~:3,6-~~ANHYDRO-L-GALACTOSE~~'>~~AAL~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.59Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cdo\|2cdo]]</div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [https://pdbe.org/2cdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [https://www.ebi.ac.uk/pdbsum/2cdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [https://pdbe.org/2cdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [https://www.ebi.ac.uk/pdbsum/2cdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdp ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q6DN99_9GAMM Q6DN99_9GAMM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Microbulbifer~~ degradans 2-40]]		[[Category: Saccharophagus degradans 2-40]]
	[[Category: Bolam~~, D N~~]]		[[Category: Bolam DN]]
	[[Category: Boraston~~, A B]]~~		[[Category: Boraston AB]]
	~~[[Category: Bueren, A L.Van~~]]		[[Category: Czjzek M]]
	[[Category: Czjzek, M]]		[[Category: Davies GJ]]
	[[Category: Davies~~, G J~~]]		[[Category: Gilbert HJ]]
	[[Category: Gilbert~~, H J~~]]		[[Category: Henshaw J]]
	[[Category: Henshaw, J]]		[[Category: Horne A]]
	[[Category: Horne, A]]		[[Category: Hutcheson SW]]
	[[Category: Hutcheson~~, S W~~]]		[[Category: Money VA]]
	[[Category: Money~~, V A~~]]		[[Category: Van Bueren AL]]
	[[Category: ~~Weiner, R M~~]]		[[Category: Weiner RM]]
	[[Category: ~~Carbohydrate-binding module]]~~
	~~[[Category: Hydrolase~~]]

OCA at 10:01, 12 May 2021

2021-05-12T10:01:31Z

← Older revision		Revision as of 10:01, 12 May 2021
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	<StructureSection load='2cdp' size='340' side='right'caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='2cdp' size='340' side='right'caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Microbulbifer_degradans_2-40 Microbulbifer degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~AAL~~:~~3,6-ANHYDRO-L-GALACTOSE~~'>~~AAL~~</scene>, <scene name='pdbligand=CA:~~CALCIUM~~+ION'>CA</scene>, <scene name='pdbligand=CL:~~CHLORIDE+ION~~'>CL</scene>, <scene name='pdbligand=~~EDO~~:1,2-~~ETHANEDIOL~~'>~~EDO~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cdo\|2cdo]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [~~http~~://pdbe.org/2cdp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cdp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [https://pdbe.org/2cdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [https://www.ebi.ac.uk/pdbsum/2cdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdp ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
			[[Category: Microbulbifer degradans 2-40]]
	[[Category: Bolam, D N]]		[[Category: Bolam, D N]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 07:18, 7 August 2019

2019-08-07T07:18:22Z

← Older revision		Revision as of 07:18, 7 August 2019
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	==Structure of a CBM6 in complex with neoagarohexaose==		==Structure of a CBM6 in complex with neoagarohexaose==
	<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='2cdp' size='340' side='right'caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cdp_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cdp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Bolam, D N]]		[[Category: Bolam, D N]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 09:55, 3 August 2017

2017-08-03T09:55:03Z

← Older revision		Revision as of 09:55, 3 August 2017
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	==~~STRUCTURE OF A~~ CBM6 ~~IN COMPLEX WITH NEOAGAROHEXAOSE~~==
			==Structure of a CBM6 in complex with neoagarohexaose==
	<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Microbulbifer_degradans_2-40 Microbulbifer degradans 2-40]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:~~CALCIUM+ION~~'>CA</scene>, <scene name='pdbligand=CL:~~CHLORIDE~~+ION'>CL</scene>, <scene name='pdbligand=~~EDO~~:~~1,2-ETHANEDIOL~~'>~~EDO~~</scene>, <scene name='pdbligand=~~AAL~~:3,6-~~ANHYDRO-L-GALACTOSE~~'>~~AAL~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://pdbe.org/2cdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://pdbe.org/2cdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cdp ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Microbulbifer degradans 2-40]]~~
	[[Category: Bolam, D N]]		[[Category: Bolam, D N]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 00:14, 9 February 2016

2016-02-09T00:14:33Z

← Older revision		Revision as of 00:14, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cdp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:44, 10 September 2015

2015-09-10T16:44:07Z

← Older revision		Revision as of 16:44, 10 September 2015
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	<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharophagus_degradans Saccharophagus~~ degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Microbulbifer_degradans_2-40 Microbulbifer degradans 2-40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://pdbe.org/2cdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2cdp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Saccharophagus~~ degradans]]		[[Category: Microbulbifer degradans 2-40]]
	[[Category: Bolam, D N]]		[[Category: Bolam, D N]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 17:13, 15 January 2015

2015-01-15T17:13:47Z

← Older revision		Revision as of 17:13, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharophagus_degradans Saccharophagus degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharophagus_degradans Saccharophagus degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Saccharophagus degradans]]		[[Category: Saccharophagus degradans]]
	[[Category: Bolam, D N.]]		[[Category: Bolam, D N]]
	[[Category: Boraston, A B.]]		[[Category: Boraston, A B]]
	[[Category: Bueren, A L.Van.]]		[[Category: Bueren, A L.Van]]
	[[Category: Czjzek, M.]]		[[Category: Czjzek, M]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J]]
	[[Category: Gilbert, H J.]]		[[Category: Gilbert, H J]]
	[[Category: Henshaw, J.]]		[[Category: Henshaw, J]]
	[[Category: Horne, A.]]		[[Category: Horne, A]]
	[[Category: Hutcheson, S W.]]		[[Category: Hutcheson, S W]]
	[[Category: Money, V A.]]		[[Category: Money, V A]]
	[[Category: Weiner, R M.]]		[[Category: Weiner, R M]]
	[[Category: Carbohydrate-binding module]]		[[Category: Carbohydrate-binding module]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 00:33, 30 September 2014

2014-09-30T00:33:42Z

← Older revision		Revision as of 00:33, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2cdp~~.~~png~~\|~~left~~\|~~200px~~]]		==STRUCTURE OF A CBM6 IN COMPLEX WITH NEOAGAROHEXAOSE==
			<StructureSection load='2cdp' size='340' side='right' caption='[[2cdp]], [[Resolution\|resolution]] 1.59Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharophagus_degradans Saccharophagus degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CDP FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=AAL:3,6-ANHYDRO-L-GALACTOSE'>AAL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2cdo\|2cdo]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cdp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cdp RCSB], [http://www.ebi.ac.uk/pdbsum/2cdp PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/2cdp_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Carbohydrate recognition is central to the biological and industrial exploitation of plant structural polysaccharides. These insoluble polymers are recalcitrant to microbial degradation, and enzymes that catalyze this process generally contain non-catalytic carbohydrate binding modules (CBMs) that potentiate activity by increasing substrate binding. Agarose, a repeat of the disaccharide 3,6-anhydro-alpha-L-galactose-(1,3)-beta-D-galactopyranose-(1,4), is the dominant matrix polysaccharide in marine algae, yet the role of CBMs in the hydrolysis of this important polymer has not previously been explored. Here we show that family 6 CBMs, present in two different beta-agarases, bind specifically to the non-reducing end of agarose chains, recognizing only the first repeat of the disaccharide. The crystal structure of one of these modules Aga16B-CBM6-2, in complex with neoagarohexaose, reveals the mechanism by which the protein displays exquisite specificity, targeting the equatorial O4 and the axial O3 of the anhydro-L-galactose. Targeting of the CBM6 to the non-reducing end of agarose chains may direct the appended catalytic modules to areas of the plant cell wall attacked by beta-agarases where the matrix polysaccharide is likely to be more amenable to further enzymic hydrolysis.

	~~{{STRUCTURE_2cdp\| PDB=2cdp \| SCENE= }}~~		Family 6 carbohydrate binding modules in beta-agarases display exquisite selectivity for the non-reducing termini of agarose chains.,Henshaw J, Horne-Bitschy A, van Bueren AL, Money VA, Bolam DN, Czjzek M, Ekborg NA, Weiner RM, Hutcheson SW, Davies GJ, Boraston AB, Gilbert HJ J Biol Chem. 2006 Jun 23;281(25):17099-107. Epub 2006 Apr 6. PMID:16601125<ref>PMID:16601125</ref>

	~~===STRUCTURE OF A CBM6 IN COMPLEX WITH NEOAGAROHEXAOSE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16601125}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2cdp]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharophagus_degradans Saccharophagus degradans]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016601125<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Saccharophagus degradans]]		[[Category: Saccharophagus degradans]]
	[[Category: Bolam, D N.]]		[[Category: Bolam, D N.]]

OCA: Protected "2cdp" [edit=sysop:move=sysop]

2013-01-06T09:56:08Z

Protected "2cdp" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:56, 6 January 2013
(No difference)

OCA at 09:56, 6 January 2013

2013-01-06T09:56:05Z

← Older revision		Revision as of 09:56, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2cdp.png\|left\|200px]]		[[Image:2cdp.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2cdp", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2cdp\| PDB=2cdp \| SCENE= }}		{{STRUCTURE_2cdp\| PDB=2cdp \| SCENE= }}

	===STRUCTURE OF A CBM6 IN COMPLEX WITH NEOAGAROHEXAOSE===		===STRUCTURE OF A CBM6 IN COMPLEX WITH NEOAGAROHEXAOSE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16601125}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16601125 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_16601125}}		{{ABSTRACT_PUBMED_16601125}}

	==About this Structure==		==About this Structure==
	~~2CDP~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Saccharophagus_degradans Saccharophagus degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA].		[[2cdp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharophagus_degradans Saccharophagus degradans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CDP OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16601125~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016601125</ref><references group="xtra"/>
	[[Category: Saccharophagus degradans]]		[[Category: Saccharophagus degradans]]
	[[Category: Bolam, D N.]]		[[Category: Bolam, D N.]]
Line 38:		Line 26:
	[[Category: Carbohydrate-binding module]]		[[Category: Carbohydrate-binding module]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:47:33 2009''~~