2cfd - Revision history

OCA at 08:25, 9 April 2025

2025-04-09T08:25:32Z

← Older revision		Revision as of 08:25, 9 April 2025
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfd_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 11:26, 22 May 2024

2024-05-22T11:26:14Z

← Older revision		Revision as of 11:26, 22 May 2024
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	<StructureSection load='2cfd' size='340' side='right'caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2cfd' size='340' side='right'caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter~~ globiformis~~" (conn 1928) bergey et al. 1930~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene~~></td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [https://pdbe.org/2cfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [https://www.ebi.ac.uk/pdbsum/2cfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [https://pdbe.org/2cfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [https://www.ebi.ac.uk/pdbsum/2cfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfd ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/PAOX_ARTGO PAOX_ARTGO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Arthrobacter globiformis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Oxidoreductase]]~~		[[Category: Contakes SM]]
	[[Category: Contakes~~, S M~~]]		[[Category: Dooley DM]]
	[[Category: Dooley~~, D M~~]]		[[Category: Duff AP]]
	[[Category: Duff~~, A P~~]]		[[Category: Dunn AR]]
	[[Category: Dunn~~, A R~~]]		[[Category: Freeman HC]]
	[[Category: Freeman~~, H C~~]]		[[Category: Gray HB]]
	[[Category: Gray~~, H B~~]]		[[Category: Guss JM]]
	[[Category: Guss~~, J M~~]]		[[Category: Halpern-Manners NW]]
	[[Category: Halpern-Manners~~, N W~~]]		[[Category: Juda GA]]
	[[Category: Juda~~, G A~~]]		[[Category: Langley DB]]
	[[Category: Langley~~, D B]]~~
	~~[[Category: Amine oxidase]]~~
	~~[[Category: Arthrobacter globiformi]]~~
	~~[[Category: Competitive inhibition]]~~
	~~[[Category: Copper containing]]~~
	~~[[Category: Metal-binding]]~~
	~~[[Category: Quinone]]~~
	~~[[Category: Ruthenium diimine wire]]~~
	~~[[Category: Tpq~~]]

OCA at 10:34, 17 February 2021

2021-02-17T10:34:12Z

← Older revision		Revision as of 10:34, 17 February 2021
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	<StructureSection load='2cfd' size='340' side='right'caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2cfd' size='340' side='right'caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [~~http~~://pdbe.org/2cfd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cfd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [https://pdbe.org/2cfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [https://www.ebi.ac.uk/pdbsum/2cfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfd ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[Copper ~~Amine Oxidase~~\|Copper ~~Amine Oxidase~~]]		*[[Copper amine oxidase 3D structures\|Copper amine oxidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:58, 10 May 2019

2019-05-10T11:58:46Z

← Older revision		Revision as of 11:58, 10 May 2019
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	==AGAO in complex with wc4l3 (Ru-wire inhibitor, 4-carbon linker, lambda enantiomer, data set 3)==		==AGAO in complex with wc4l3 (Ru-wire inhibitor, 4-carbon linker, lambda enantiomer, data set 3)==
	<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2cfd' size='340' side='right'caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Contakes, S M]]		[[Category: Contakes, S M]]

OCA at 08:33, 23 May 2018

2018-05-23T08:33:26Z

← Older revision		Revision as of 08:33, 23 May 2018
Line 1:		Line 1:
	==AGAO ~~IN COMPLEX WITH WC4L3~~ (RU-~~WIRE INHIBITOR~~, 4-~~CARBON LINKER~~, ~~LAMBDA ENANTIOMER~~, ~~DATA SET~~ 3)==
			==AGAO in complex with wc4l3 (Ru-wire inhibitor, 4-carbon linker, lambda enantiomer, data set 3)==
	<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://pdbe.org/2cfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://pdbe.org/2cfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfd ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfd_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cfd ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:53, 12 September 2015

2015-09-12T00:53:50Z

← Older revision		Revision as of 00:53, 12 September 2015
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	<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arthrobacter_globiformis Arthrobacter~~ globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_globiformis"_(conn_1928)_bergey_et_al._1930 "achromobacter globiformis" (conn 1928) bergey et al. 1930]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://pdbe.org/2cfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2cfd" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Arthrobacter globiformis]]~~
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Contakes, S M]]		[[Category: Contakes, S M]]

OCA at 18:18, 15 January 2015

2015-01-15T18:18:27Z

← Older revision		Revision as of 18:18, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	[[Category: Arthrobacter globiformis]]		[[Category: Arthrobacter globiformis]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Contakes, S M.]]		[[Category: Contakes, S M]]
	[[Category: Dooley, D M.]]		[[Category: Dooley, D M]]
	[[Category: Duff, A P.]]		[[Category: Duff, A P]]
	[[Category: Dunn, A R.]]		[[Category: Dunn, A R]]
	[[Category: Freeman, H C.]]		[[Category: Freeman, H C]]
	[[Category: Gray, H B.]]		[[Category: Gray, H B]]
	[[Category: Guss, J M.]]		[[Category: Guss, J M]]
	[[Category: Halpern-Manners, N W.]]		[[Category: Halpern-Manners, N W]]
	[[Category: Juda, G A.]]		[[Category: Juda, G A]]
	[[Category: Langley, D B.]]		[[Category: Langley, D B]]
	[[Category: Amine oxidase]]		[[Category: Amine oxidase]]
	[[Category: Arthrobacter globiformi]]		[[Category: Arthrobacter globiformi]]
Line 51:		Line 51:
	[[Category: Copper containing]]		[[Category: Copper containing]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	~~[[Category: Oxidoreductase]]~~
	[[Category: Quinone]]		[[Category: Quinone]]
	[[Category: Ruthenium diimine wire]]		[[Category: Ruthenium diimine wire]]
	[[Category: Tpq]]		[[Category: Tpq]]

OCA at 05:16, 29 September 2014

2014-09-29T05:16:57Z

← Older revision		Revision as of 05:16, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2cfd~~.~~png~~\|~~left~~\|~~200px~~]]		==AGAO IN COMPLEX WITH WC4L3 (RU-WIRE INHIBITOR, 4-CARBON LINKER, LAMBDA ENANTIOMER, DATA SET 3)==
			<StructureSection load='2cfd' size='340' side='right' caption='[[2cfd]], [[Resolution\|resolution]] 1.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFD FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=R4A:BIS[1H,1H-2,2-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM'>R4A</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1av4\|1av4]], [[1avk\|1avk]], [[1avl\|1avl]], [[1iqx\|1iqx]], [[1iqy\|1iqy]], [[1iu7\|1iu7]], [[1ivu\|1ivu]], [[1ivv\|1ivv]], [[1ivw\|1ivw]], [[1ivx\|1ivx]], [[1rjo\|1rjo]], [[1sih\|1sih]], [[1sii\|1sii]], [[1ui7\|1ui7]], [[1ui8\|1ui8]], [[1w4n\|1w4n]], [[1w5z\|1w5z]], [[1w6c\|1w6c]], [[1w6g\|1w6g]], [[1wmn\|1wmn]], [[1wmo\|1wmo]], [[1wmp\|1wmp]], [[2bt3\|2bt3]], [[2cfg\|2cfg]], [[2cfk\|2cfk]], [[2cfl\|2cfl]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.21 and 1.4.3.22 1.4.3.21 and 1.4.3.22] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfd RCSB], [http://www.ebi.ac.uk/pdbsum/2cfd PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfd_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The copper amine oxidase from Arthrobacter globiformis (AGAO) is reversibly inhibited by molecular wires comprising a Ru(II) complex head group and an aromatic tail group joined by an alkane linker. The crystal structures of a series of Ru(II)-wire-AGAO complexes differing with respect to the length of the alkane linker have been determined. All wires lie in the AGAO active-site channel, with their aromatic tail group in contact with the trihydroxyphenylalanine quinone (TPQ) cofactor of the enzyme. The TPQ cofactor is consistently in its active ("off-Cu") conformation, and the side chain of the so-called "gate" residue Tyr296 is consistently in the "gate-open" conformation. Among the wires tested, the most stable complex is produced when the wire has a -(CH2)4- linker. In this complex, the Ru(II)(phen)(bpy)2 head group is level with the protein molecular surface. Crystal structures of AGAO in complex with optically pure forms of the C4 wire show that the linker and head group in the two enantiomers occupy slightly different positions in the active-site channel. Both the Lambda and Delta isomers are effective competitive inhibitors of amine oxidation. Remarkably, inhibition by the C4 wire shows a high degree of selectivity for AGAO in comparison with other copper-containing amine oxidases.

	~~{{STRUCTURE_2cfd\| PDB=2cfd \| SCENE= }}~~		Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis.,Langley DB, Brown DE, Cheruzel LE, Contakes SM, Duff AP, Hilmer KM, Dooley DM, Gray HB, Guss JM, Freeman HC J Am Chem Soc. 2008 Jun 25;130(25):8069-78. Epub 2008 May 29. PMID:18507382<ref>PMID:18507382</ref>

	~~===AGAO IN COMPLEX WITH WC4L3 (RU-WIRE INHIBITOR~~, ~~4-CARBON LINKER, LAMBDA ENANTIOMER, DATA SET 3)===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18507382}}~~

	~~==About this Structure==~~
	~~[[2cfd]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2CFD OCA].~~

	==See Also==		==See Also==
	*[[Copper Amine Oxidase\|Copper Amine Oxidase]]		*[[Copper Amine Oxidase\|Copper Amine Oxidase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018507382<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Arthrobacter globiformis]]		[[Category: Arthrobacter globiformis]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 21:59, 20 October 2012

2012-10-20T21:59:13Z

← Older revision		Revision as of 21:59, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2cfd]] is a 2 chain structure ~~of [[Copper Amine Oxidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA].		[[2cfd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFD OCA].

	==See Also==		==See Also==

OCA at 14:51, 27 July 2012

2012-07-27T14:51:50Z

← Older revision		Revision as of 14:51, 27 July 2012
Line 1:		Line 1:
	[[Image:2cfd.png\|left\|200px]]		[[Image:2cfd.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2cfd", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2cfd\| PDB=2cfd \| SCENE= }}		{{STRUCTURE_2cfd\| PDB=2cfd \| SCENE= }}

	===AGAO IN COMPLEX WITH WC4L3 (RU-WIRE INHIBITOR, 4-CARBON LINKER, LAMBDA ENANTIOMER, DATA SET 3)===		===AGAO IN COMPLEX WITH WC4L3 (RU-WIRE INHIBITOR, 4-CARBON LINKER, LAMBDA ENANTIOMER, DATA SET 3)===


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	{{ABSTRACT_PUBMED_18507382}}		{{ABSTRACT_PUBMED_18507382}}

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	==See Also==		==See Also==
	*[[Copper Amine Oxidase]]		*[[Copper Amine Oxidase\|Copper Amine Oxidase]]

	==Reference==		==Reference==