2cha - Revision history

OCA at 07:04, 27 September 2023

2023-09-27T07:04:48Z

← Older revision		Revision as of 07:04, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHA FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=TSU:PARA~~-~~TOLUENE+SULFONATE'>TSU</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1]~~ </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [https://pdbe.org/2cha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [https://www.ebi.ac.uk/pdbsum/2cha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cha ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [https://pdbe.org/2cha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [https://www.ebi.ac.uk/pdbsum/2cha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cha ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/CTRA_BOVIN CTRA_BOVIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	~~[[Category: Chymotrypsin]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: PDB Pioneers]]		[[Category: PDB Pioneers]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Birktoft~~, J J~~]]		[[Category: Birktoft JJ]]
	[[Category: Blow~~, D M~~]]		[[Category: Blow DM]]

OCA at 06:55, 1 December 2021

2021-12-01T06:55:44Z

← Older revision		Revision as of 06:55, 1 December 2021
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	<StructureSection load='2cha' size='340' side='right'caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cha' size='340' side='right'caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [~~http~~://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [~~http~~://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [~~http~~://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [~~http~~://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CHA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [~~http~~://pdbe.org/2cha PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cha PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cha ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [https://pdbe.org/2cha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [https://www.ebi.ac.uk/pdbsum/2cha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cha ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[CHEM2052 Tutorial\|CHEM2052 Tutorial]]
	*[[Chymotrypsin 3D structures\|Chymotrypsin 3D structures]]		*[[Chymotrypsin 3D structures\|Chymotrypsin 3D structures]]
	*[[Serine Proteases\|Serine Proteases]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:57, 26 February 2020

2020-02-26T10:57:21Z

← Older revision		Revision as of 10:57, 26 February 2020
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	==THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION==		==THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION==
	<StructureSection load='2cha' size='340' side='right' caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cha' size='340' side='right'caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHA FirstGlance]. <br>
Line 21:		Line 21:
	==See Also==		==See Also==
	*[[CHEM2052 Tutorial\|CHEM2052 Tutorial]]		*[[CHEM2052 Tutorial\|CHEM2052 Tutorial]]
	*[[Chymotrypsin\|Chymotrypsin]]		*[[Chymotrypsin 3D structures\|Chymotrypsin 3D structures]]
	*[[Serine Proteases\|Serine Proteases]]		*[[Serine Proteases\|Serine Proteases]]
	__TOC__		__TOC__
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	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Chymotrypsin]]		[[Category: Chymotrypsin]]
			[[Category: Large Structures]]
	[[Category: PDB Pioneers]]		[[Category: PDB Pioneers]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]

OCA at 08:18, 23 May 2018

2018-05-23T08:18:57Z

← Older revision		Revision as of 08:18, 23 May 2018
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	==THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION==		==THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION==
	<StructureSection load='2cha' size='340' side='right' caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cha' size='340' side='right' caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://pdbe.org/2cha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://pdbe.org/2cha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cha ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2cha_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2cha_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:34, 9 February 2016

2016-02-09T09:34:43Z

← Older revision		Revision as of 09:34, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cha ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 20:55, 10 September 2015

2015-09-10T20:55:58Z

← Older revision		Revision as of 20:55, 10 September 2015
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://pdbe.org/2cha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 16:35, 15 January 2015

2015-01-15T16:35:25Z

← Older revision		Revision as of 16:35, 15 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHA FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Birktoft, J J.]]		[[Category: Birktoft, J J]]
	[[Category: Blow, D M.]]		[[Category: Blow, D M]]

OCA at 11:12, 3 October 2014

2014-10-03T11:12:05Z

← Older revision		Revision as of 11:12, 3 October 2014
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	~~[[Image:2cha.png\|left\|200px]]~~		==THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION==
			<StructureSection load='2cha' size='340' side='right' caption='[[2cha]], [[Resolution\|resolution]] 2.00Å' scene=''>
	~~{{STRUCTURE_2cha\| PDB=2cha \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHA FirstGlance]. <br>
	===THE STRUCTURE OF CRYSTALLINE ALPHA-CHYMOTRYPSIN, $V.THE ATOMIC STRUCTURE OF TOSYL-ALPHA-CHYMOTRYPSIN AT 2 ANGSTROMS RESOLUTION===		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene><br>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymotrypsin Chymotrypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.1 3.4.21.1] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cha OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cha RCSB], [http://www.ebi.ac.uk/pdbsum/2cha PDBsum]</span></td></tr>
	==~~About this Structure~~==		<table>
	[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA].		== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2cha_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>

	==See Also==		==See Also==
			*[[CHEM2052 Tutorial\|CHEM2052 Tutorial]]
	*[[Chymotrypsin\|Chymotrypsin]]		*[[Chymotrypsin\|Chymotrypsin]]
			*[[Serine Proteases\|Serine Proteases]]
	~~==Reference==~~		__TOC__
	<~~ref group="xtra">PMID:005069789</ref><references group="xtra"~~/>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Chymotrypsin]]		[[Category: Chymotrypsin]]

OCA at 13:26, 20 October 2012

2012-10-20T13:26:07Z

← Older revision		Revision as of 13:26, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
	[[2cha]] is a 6 chain structure ~~of [[Chymotrypsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA].		[[2cha]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA].

	==See Also==		==See Also==

OCA at 11:56, 26 July 2012

2012-07-26T11:56:27Z

← Older revision		Revision as of 11:56, 26 July 2012
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	[[Image:2cha.png\|left\|200px]]		[[Image:2cha.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2cha", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2cha\| PDB=2cha \| SCENE= }}		{{STRUCTURE_2cha\| PDB=2cha \| SCENE= }}

Line 13:		Line 7:

	==About this Structure==		==About this Structure==
	[[2cha]] is a 6 chain structure of [[Chymotrypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA].		[[2cha]] is a 6 chain structure of [[Chymotrypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The October 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Trypsin'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_10 10.2210/rcsb_pdb/mom_2003_10]. The October 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''PDB Pioneers'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_10 10.2210/rcsb_pdb/mom_2011_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHA OCA].

	==See Also==		==See Also==
	*[[Chymotrypsin]]		*[[Chymotrypsin\|Chymotrypsin]]
	*[[Serine Proteases]]
	*[[Serine Proteases: A Tutorial of Chymotrypsin~~%2C Trypsin and Elastase~~]]

	==Reference==		==Reference==
Line 24:		Line 16:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Chymotrypsin]]		[[Category: Chymotrypsin]]
			[[Category: PDB Pioneers]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Birktoft, J J.]]		[[Category: Birktoft, J J.]]
	[[Category: Blow, D M.]]		[[Category: Blow, D M.]]