2chf - Revision history

OCA at 09:17, 14 February 2024

2024-02-14T09:17:57Z

← Older revision		Revision as of 09:17, 14 February 2024
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	<StructureSection load='2chf' size='340' side='right'caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2chf' size='340' side='right'caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [https://pdbe.org/2chf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [https://www.ebi.ac.uk/pdbsum/2chf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chf ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [https://pdbe.org/2chf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [https://www.ebi.ac.uk/pdbsum/2chf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.		[https://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2chf ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2chf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The response regulator protein of bacterial chemotaxis, CheY, is representative of a large family of signal transduction proteins that function as phosphorylation-activated switches to regulate the activities of associated effector domains. These regulators catalyze the metal ion-dependent phosphoryl transfer and dephosphorylation reactions that control the effector activities. The crystal structures of Salmonella typhimurium CheY with and without Mg2+ bound at the active site have been determined and refined at 1.8-A resolution. While the overall structures of metal-bound and metal-free CheY are similar, significant rearrangements occur within the active site involving the three most highly conserved residues of the response regulator family. Conservation of the cluster of carboxylate side chains at the active site of response regulator domains can be rationalized in terms of their role in coordinating the catalytically essential divalent metal ion. The Mg2+ coordination geometry provides insights to the mechanism of phosphoryl transfer.

	Structure of the Mg(2+)-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis.,Stock AM, Martinez-Hackert E, Rasmussen BF, West AH, Stock JB, Ringe D, Petsko GA Biochemistry. 1993 Dec 14;32(49):13375-80. PMID:8257674<ref>PMID:8257674</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>~~

	==See Also==		==See Also==
	*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]		*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Martinez-Hackert, E]]		[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
	[[Category: Petsko, G]]		[[Category: Martinez-Hackert E]]
	[[Category: Rasmussen, B]]		[[Category: Petsko G]]
	[[Category: Ringe, D]]		[[Category: Rasmussen B]]
	[[Category: Stock, A]]		[[Category: Ringe D]]
	[[Category: Stock, J]]		[[Category: Stock A]]
	[[Category: West, A]]		[[Category: Stock J]]
	~~[[Category: Signal transduction protein~~]]		[[Category: West A]]

OCA at 20:35, 20 October 2021

2021-10-20T20:35:22Z

← Older revision		Revision as of 20:35, 20 October 2021
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	<StructureSection load='2chf' size='340' side='right'caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2chf' size='340' side='right'caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [~~http~~://pdbe.org/2chf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2chf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2chf ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [https://pdbe.org/2chf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [https://www.ebi.ac.uk/pdbsum/2chf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.		[[https://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:20, 11 December 2019

2019-12-11T19:20:35Z

← Older revision		Revision as of 19:20, 11 December 2019
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	==STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS==		==STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS==
	<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2chf' size='340' side='right'caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chf_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</div>		</div>
	<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Martinez-Hackert, E]]		[[Category: Martinez-Hackert, E]]
	[[Category: Petsko, G]]		[[Category: Petsko, G]]

OCA at 07:05, 29 November 2017

2017-11-29T07:05:17Z

← Older revision		Revision as of 07:05, 29 November 2017
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	==STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS==		==STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS==
	<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://pdbe.org/2chf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://pdbe.org/2chf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2chf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Chemotaxis protein\|Chemotaxis protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:27, 9 February 2016

2016-02-09T20:27:17Z

← Older revision		Revision as of 20:27, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2chf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:44, 11 September 2015

2015-09-11T01:44:54Z

← Older revision		Revision as of 01:44, 11 September 2015
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	<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://pdbe.org/2chf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2chf" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]~~
	[[Category: Martinez-Hackert, E]]		[[Category: Martinez-Hackert, E]]
	[[Category: Petsko, G]]		[[Category: Petsko, G]]

OCA at 09:20, 25 December 2014

2014-12-25T09:20:02Z

← Older revision		Revision as of 09:20, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CHEY_SALTY CHEY_SALTY]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation. Shows autophosphatase activity which is enhanced by CheZ.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Martinez-Hackert, E.]]		[[Category: Martinez-Hackert, E]]
	[[Category: Petsko, G.]]		[[Category: Petsko, G]]
	[[Category: Rasmussen, B.]]		[[Category: Rasmussen, B]]
	[[Category: Ringe, D.]]		[[Category: Ringe, D]]
	[[Category: Stock, A.]]		[[Category: Stock, A]]
	[[Category: Stock, J.]]		[[Category: Stock, J]]
	[[Category: West, A.]]		[[Category: West, A]]
	[[Category: Signal transduction protein]]		[[Category: Signal transduction protein]]

OCA at 00:05, 30 September 2014

2014-09-30T00:05:30Z

← Older revision		Revision as of 00:05, 30 September 2014
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	[[Image:~~2chf~~.~~png~~\|~~left~~\|~~200px~~]]		==STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS==
			<StructureSection load='2chf' size='340' side='right' caption='[[2chf]], [[Resolution\|resolution]] 1.80Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2chf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHF FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chf RCSB], [http://www.ebi.ac.uk/pdbsum/2chf PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chf_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The response regulator protein of bacterial chemotaxis, CheY, is representative of a large family of signal transduction proteins that function as phosphorylation-activated switches to regulate the activities of associated effector domains. These regulators catalyze the metal ion-dependent phosphoryl transfer and dephosphorylation reactions that control the effector activities. The crystal structures of Salmonella typhimurium CheY with and without Mg2+ bound at the active site have been determined and refined at 1.8-A resolution. While the overall structures of metal-bound and metal-free CheY are similar, significant rearrangements occur within the active site involving the three most highly conserved residues of the response regulator family. Conservation of the cluster of carboxylate side chains at the active site of response regulator domains can be rationalized in terms of their role in coordinating the catalytically essential divalent metal ion. The Mg2+ coordination geometry provides insights to the mechanism of phosphoryl transfer.

	~~{{STRUCTURE_2chf\| PDB=2chf \| SCENE= }}~~		Structure of the Mg(2+)-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis.,Stock AM, Martinez-Hackert E, Rasmussen BF, West AH, Stock JB, Ringe D, Petsko GA Biochemistry. 1993 Dec 14;32(49):13375-80. PMID:8257674<ref>PMID:8257674</ref>

	~~===STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_8257674}}~~		==See Also==
			*[[Chemotaxis protein\|Chemotaxis protein]]
	==~~About this Structure~~==		== References ==
	[[~~2chf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA~~].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:008257674<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Martinez-Hackert, E.]]		[[Category: Martinez-Hackert, E.]]

OCA: Protected "2chf" [edit=sysop:move=sysop]

2013-01-06T09:32:12Z

Protected "2chf" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:32, 6 January 2013
(No difference)

OCA at 09:32, 6 January 2013

2013-01-06T09:32:09Z

← Older revision		Revision as of 09:32, 6 January 2013
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	[[Image:2chf.png\|left\|200px]]		[[Image:2chf.png\|left\|200px]]

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	{{STRUCTURE_2chf\| PDB=2chf \| SCENE= }}		{{STRUCTURE_2chf\| PDB=2chf \| SCENE= }}

	===STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS===		===STRUCTURE OF THE MG2+-BOUND FORM OF CHEY AND THE MECHANISM OF PHOSPHORYL TRANSFER IN BACTERIAL CHEMOTAXIS===


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	~~The line below this paragraph, {{ABSTRACT_PUBMED_8257674}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 8257674 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_8257674}}		{{ABSTRACT_PUBMED_8257674}}

	==About this Structure==		==About this Structure==
	~~2CHF~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Salmonella_typhimurium~~ Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA].		[[2chf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHF OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~8257674~~</ref><references group="xtra"/>		<ref group="xtra">PMID:008257674</ref><references group="xtra"/>
	[[Category: Salmonella typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Martinez-Hackert, E.]]		[[Category: Martinez-Hackert, E.]]
	[[Category: Petsko, G.]]		[[Category: Petsko, G.]]
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	[[Category: West, A.]]		[[Category: West, A.]]
	[[Category: Signal transduction protein]]		[[Category: Signal transduction protein]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:31:06 2009''~~