2cs4 - Revision history

OCA at 11:30, 22 May 2024

2024-05-22T11:30:02Z

← Older revision		Revision as of 11:30, 22 May 2024
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	==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==		==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==
	<StructureSection load='2cs4' size='340' side='right'caption='[[2cs4~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2cs4' size='340' side='right'caption='[[2cs4]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>C12orf2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~9606 HUMAN])~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [https://pdbe.org/2cs4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [https://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [https://pdbe.org/2cs4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [https://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[[https://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.		[https://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
			== Function ==
			[https://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hayashi, F]]		[[Category: Hayashi F]]
	[[Category: Nagashima, T]]		[[Category: Nagashima T]]
	~~[[Category: Structural genomic~~]]		[[Category: Yokoyama S]]
	[[Category: Yokoyama, S]]
	~~[[Category: Gtp binding]]~~
	~~[[Category: National project on protein structural and functional analyse]]~~
	~~[[Category: Nppsfa]]~~
	~~[[Category: Rsgi]]~~
	~~[[Category: Signaling protein]]~~
	~~[[Category: Ubiquitin fold~~]]

OCA at 11:48, 3 February 2021

2021-02-03T11:48:57Z

← Older revision		Revision as of 11:48, 3 February 2021
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	==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==		==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==
	<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2cs4' size='340' side='right'caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [~~http~~://pdbe.org/2cs4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs4 ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [https://pdbe.org/2cs4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [https://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs4 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
	[[~~http~~://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.		[[https://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Hayashi, F]]		[[Category: Hayashi, F]]
	[[Category: Nagashima, T]]		[[Category: Nagashima, T]]

OCA at 08:40, 23 May 2018

2018-05-23T08:40:00Z

← Older revision		Revision as of 08:40, 23 May 2018
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	==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==		==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==
	<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
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	<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://pdbe.org/2cs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://pdbe.org/2cs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs4 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs4_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:50, 9 February 2016

2016-02-09T17:50:37Z

← Older revision		Revision as of 17:50, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cs4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 00:35, 11 September 2015

2015-09-11T00:35:36Z

← Older revision		Revision as of 00:35, 11 September 2015
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	<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://pdbe.org/2cs4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Hayashi, F]]		[[Category: Hayashi, F]]
	[[Category: Nagashima, T]]		[[Category: Nagashima, T]]

OCA at 08:27, 25 December 2014

2014-12-25T08:27:18Z

← Older revision		Revision as of 08:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
	<table>		</table>
	== Disease ==		== Disease ==
	[[http://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.		[[http://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
	~~== Function ==~~

	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Hayashi, F.]]		[[Category: Hayashi, F]]
	[[Category: Nagashima, T.]]		[[Category: Nagashima, T]]
	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]		[[Category: Structural genomic]]
	[[Category: Yokoyama, S.]]		[[Category: Yokoyama, S]]
	[[Category: Gtp binding]]		[[Category: Gtp binding]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
	~~[[Category: Riken structural genomics/proteomics initiative]]~~
	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	~~[[Category: Structural genomic]]~~
	[[Category: Ubiquitin fold]]		[[Category: Ubiquitin fold]]

OCA at 02:09, 30 September 2014

2014-09-30T02:09:04Z

← Older revision		Revision as of 02:09, 30 September 2014
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	~~{{STRUCTURE_2cs4\| PDB=2cs4 \| SCENE= }}~~		==Solution structure of N-terminal domain of chromosome 12 open reading frame 2==
	===Solution structure of N-terminal domain of chromosome 12 open reading frame 2===		<StructureSection load='2cs4' size='340' side='right' caption='[[2cs4]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
			== Structural highlights ==
	==Disease==		<table><tr><td colspan='2'>[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CS4 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">C12orf2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cs4 RCSB], [http://www.ebi.ac.uk/pdbsum/2cs4 PDBsum], [http://www.topsan.org/Proteins/RSGI/2cs4 TOPSAN]</span></td></tr>
			<table>
			== Disease ==
	[[http://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.		[[http://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.
			== Function ==

	==~~About this Structure~~==		== Evolutionary Conservation ==
	[[~~2cs4~~]] ~~is a 1 chain~~ structure ~~with sequence from~~ [http://en.~~wikipedia~~.~~org/wiki~~/~~Homo_sapiens Homo sapiens~~]. ~~Full experimental information is~~ available from [http://~~oca~~.~~weizmann~~.ac.il/~~oca-bin~~/~~ocashort~~?id=~~2CS4 OCA~~].		[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs4_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Hayashi, F.]]		[[Category: Hayashi, F.]]

OCA at 16:45, 24 March 2013

2013-03-24T16:45:48Z

← Older revision		Revision as of 16:45, 24 March 2013
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	~~[[Image:2cs4.png\|left\|200px]]~~

	{{STRUCTURE_2cs4\| PDB=2cs4 \| SCENE= }}		{{STRUCTURE_2cs4\| PDB=2cs4 \| SCENE= }}

	===Solution structure of N-terminal domain of chromosome 12 open reading frame 2===		===Solution structure of N-terminal domain of chromosome 12 open reading frame 2===

			==Disease==
			[[http://www.uniprot.org/uniprot/RASF8_HUMAN RASF8_HUMAN]] Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.

	==About this Structure==		==About this Structure==

OCA: Protected "2cs4" [edit=sysop:move=sysop]

2013-01-06T11:21:55Z

Protected "2cs4" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:21, 6 January 2013
(No difference)

OCA at 11:21, 6 January 2013

2013-01-06T11:21:51Z

← Older revision		Revision as of 11:21, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2cs4.png\|left\|200px]]		[[Image:2cs4.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2cs4", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2cs4\| PDB=2cs4 \| SCENE= }}		{{STRUCTURE_2cs4\| PDB=2cs4 \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
	~~2CS4~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA].		[[2cs4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS4 OCA].
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Hayashi, F.]]		[[Category: Hayashi, F.]]
Line 28:		Line 21:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Ubiquitin fold]]		[[Category: Ubiquitin fold]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 11:14:23 2009''~~