2csd - Revision history

OCA at 09:04, 6 November 2024

2024-11-06T09:04:15Z

← Older revision		Revision as of 09:04, 6 November 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [https://pdbe.org/2csd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [https://www.ebi.ac.uk/pdbsum/2csd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [https://pdbe.org/2csd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [https://www.ebi.ac.uk/pdbsum/2csd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:12, 8 February 2023

2023-02-08T07:12:42Z

← Older revision		Revision as of 07:12, 8 February 2023
Line 3:		Line 3:
	<StructureSection load='2csd' size='340' side='right'caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2csd' size='340' side='right'caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Dsm_6324 Dsm 6324~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2csb\|2csb]]</div></td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [https://pdbe.org/2csd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [https://www.ebi.ac.uk/pdbsum/2csd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [https://pdbe.org/2csd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [https://www.ebi.ac.uk/pdbsum/2csd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q977W1_9EURY Q977W1_9EURY]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Dsm 6324]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Mondragon, A~~]]		[[Category: Methanopyrus kandleri]]
	[[Category: ~~Patel,~~ A]]		[[Category: Mondragon A]]
	[[Category: ~~Slesarev,~~ A]]		[[Category: Patel A]]
	[[Category: ~~Taneja, B~~]]		[[Category: Slesarev A]]
	[[Category: ~~Helix-hairpin-helix]]~~		[[Category: Taneja B]]
	~~[[Category: Helix-turn-helix]]~~
	~~[[Category: Hhh motif]]~~
	~~[[Category: Isomerase]]~~
	~~[[Category: Three helix bundle]]~~
	~~[[Category: Topoisomerase ib]]~~
	~~[[Category: Topoisomerase v~~]]

OCA at 09:47, 5 May 2021

2021-05-05T09:47:51Z

← Older revision		Revision as of 09:47, 5 May 2021
Line 3:		Line 3:
	<StructureSection load='2csd' size='340' side='right'caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2csd' size='340' side='right'caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2csb\|2csb]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [~~http~~://pdbe.org/2csd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2csd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [https://pdbe.org/2csd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [https://www.ebi.ac.uk/pdbsum/2csd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:

	==See Also==		==See Also==
	*[[Topoisomerase\|Topoisomerase]]		*[[Topoisomerase 3D structures\|Topoisomerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:16, 24 July 2019

2019-07-24T07:16:29Z

← Older revision		Revision as of 07:16, 24 July 2019
Line 1:		Line 1:

	==Crystal structure of Topoisomerase V (61 kDa fragment)==		==Crystal structure of Topoisomerase V (61 kDa fragment)==
	<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2csd' size='340' side='right'caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 2csd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2csd" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Topoisomerase\|Topoisomerase]]
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Dsm 6324]]		[[Category: Dsm 6324]]
			[[Category: Large Structures]]
	[[Category: Mondragon, A]]		[[Category: Mondragon, A]]
	[[Category: Patel, A]]		[[Category: Patel, A]]

OCA at 16:30, 12 October 2017

2017-10-12T16:30:24Z

← Older revision		Revision as of 16:30, 12 October 2017
Line 1:		Line 1:

	==Crystal structure of Topoisomerase V (61 kDa fragment)==		==Crystal structure of Topoisomerase V (61 kDa fragment)==
	<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://pdbe.org/2csd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://pdbe.org/2csd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2csd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 2csd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2csd" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Topoisomerase\|Topoisomerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:01, 10 September 2015

2015-09-10T13:01:37Z

← Older revision		Revision as of 13:01, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanopyrus_kandleri Methanopyrus kandleri~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dsm_6324 Dsm 6324]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://pdbe.org/2csd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2csd" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Methanopyrus kandleri~~]]		[[Category: Dsm 6324]]
	[[Category: Mondragon, A]]		[[Category: Mondragon, A]]
	[[Category: Patel, A]]		[[Category: Patel, A]]

OCA at 18:32, 15 January 2015

2015-01-15T18:32:11Z

← Older revision		Revision as of 18:32, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>
	<table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Methanopyrus kandleri]]		[[Category: Methanopyrus kandleri]]
	[[Category: Mondragon, A.]]		[[Category: Mondragon, A]]
	[[Category: Patel, A.]]		[[Category: Patel, A]]
	[[Category: Slesarev, A.]]		[[Category: Slesarev, A]]
	[[Category: Taneja, B.]]		[[Category: Taneja, B]]
	[[Category: Helix-hairpin-helix]]		[[Category: Helix-hairpin-helix]]
	[[Category: Helix-turn-helix]]		[[Category: Helix-turn-helix]]

OCA at 04:17, 29 September 2014

2014-09-29T04:17:09Z

← Older revision		Revision as of 04:17, 29 September 2014
Line 1:		Line 1:
	[[~~Image~~:~~2csd~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of Topoisomerase V (61 kDa fragment)==
			<StructureSection load='2csd' size='340' side='right' caption='[[2csd]], [[Resolution\|resolution]] 2.90Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CSD FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2csb\|2csb]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2csd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2csd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2csd RCSB], [http://www.ebi.ac.uk/pdbsum/2csd PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Topoisomerases are involved in controlling and maintaining the topology of DNA and are present in all kingdoms of life. Unlike all other types of topoisomerases, similar type IB enzymes have only been identified in bacteria and eukarya. The only putative type IB topoisomerase in archaea is represented by Methanopyrus kandleri topoisomerase V. Despite several common functional characteristics, topoisomerase V shows no sequence similarity to other members of the same type. The structure of the 61 kDa N-terminal fragment of topoisomerase V reveals no structural similarity to other topoisomerases. Furthermore, the structure of the active site region is different, suggesting no conservation in the cleavage and religation mechanism. Additionally, the active site is buried, indicating the need of a conformational change for activity. The presence of a topoisomerase in archaea with a unique structure suggests the evolution of a separate mechanism to alter DNA.

	~~{{STRUCTURE_2csd\| PDB=2csd \| SCENE= }}~~		Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases.,Taneja B, Patel A, Slesarev A, Mondragon A EMBO J. 2006 Jan 25;25(2):398-408. Epub 2006 Jan 5. PMID:16395333<ref>PMID:16395333</ref>

	~~===Crystal structure~~ of ~~Topoisomerase V (61 kDa fragment)===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16395333}}~~

	~~==About this Structure==~~
	~~[[2csd]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2CSD OCA].~~

	==See Also==		==See Also==
	*[[Topoisomerase\|Topoisomerase]]		*[[Topoisomerase\|Topoisomerase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:016395333<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Methanopyrus kandleri]]		[[Category: Methanopyrus kandleri]]
	[[Category: Mondragon, A.]]		[[Category: Mondragon, A.]]

OCA at 10:37, 20 October 2012

2012-10-20T10:37:38Z

← Older revision		Revision as of 10:37, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2csd]] is a 2 chain structure ~~of [[Topoisomerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA].		[[2csd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanopyrus_kandleri Methanopyrus kandleri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CSD OCA].

	==See Also==		==See Also==

OCA: Protected "2csd" [edit=sysop:move=sysop]

2012-07-26T02:45:46Z

Protected "2csd" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:45, 26 July 2012
(No difference)