2cxc - Revision history

OCA at 13:44, 13 March 2024

2024-03-13T13:44:33Z

← Older revision		Revision as of 13:44, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='2cxc' size='340' side='right'caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cxc' size='340' side='right'caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aerpe Aerpe~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix_K1 Aeropyrum pernix K1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [https://pdbe.org/2cxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [https://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxc ProSAT], [https://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [https://pdbe.org/2cxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [https://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxc ProSAT], [https://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q9YAU4_AERPE Q9YAU4_AERPE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cxc ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cxc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The transcription factor NusA functions in transcriptional regulation involving termination in bacteria. A NusA homolog consisting of only the two KH domains is widely conserved in archaea, but its function remains unknown. We have found that Aeropyrum pernix NusA strongly binds to a certain CU-rich sequence near a termination signal. Our crystal structure of A. pernix NusA revealed that its spatial arrangement is quite similar to that of the KH domains of bacterial NusA. Thus, we consider archaeal NusA to have retained some functions of bacterial NusA, including the ssRNA-binding ability. Remarkable structural differences between archaeal and bacterial NusA exist at the interface with RNAP, in connection with the different NusA-binding sites around the termination signals. Transcriptional termination in archaea could differ from all of the known bacterial and eukaryal mechanisms, in terms of the combination of a bacterial factor and a eukaryal-type RNAP.

	Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA.,Shibata R, Bessho Y, Shinkai A, Nishimoto M, Fusatomi E, Terada T, Shirouzu M, Yokoyama S Biochem Biophys Res Commun. 2007 Mar 30;355(1):122-8. Epub 2007 Jan 31. PMID:17288993<ref>PMID:17288993</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 2cxc" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Aerpe~~]]		[[Category: Aeropyrum pernix K1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bessho, Y]]		[[Category: Bessho Y]]
	~~[[Category: Structural genomic~~]]		[[Category: Shibata R]]
	[[Category: Shibata, R]]		[[Category: Shirouzu M]]
	[[Category: Shirouzu, M]]		[[Category: Yokoyama S]]
	[[Category: Yokoyama, S]]
	~~[[Category: Archaeal nusa]]~~
	~~[[Category: Kh domain]]~~
	~~[[Category: National project on protein structural and functional analyse]]~~
	~~[[Category: Nppsfa]]~~
	~~[[Category: Rna binding protein]]~~
	~~[[Category: Rsgi]]~~
	~~[[Category: Transcription]]~~
	~~[[Category: Transcription termination~~]]

OCA at 07:02, 1 December 2021

2021-12-01T07:02:25Z

← Older revision		Revision as of 07:02, 1 December 2021
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	<StructureSection load='2cxc' size='340' side='right'caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cxc' size='340' side='right'caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [~~http~~://pdbe.org/2cxc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxc ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [https://pdbe.org/2cxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [https://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxc ProSAT], [https://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 11:10, 26 February 2020

2020-02-26T11:10:55Z

← Older revision		Revision as of 11:10, 26 February 2020
Line 1:		Line 1:

	==Crystal structure of archaeal transcription termination factor NusA==		==Crystal structure of archaeal transcription termination factor NusA==
	<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cxc' size='340' side='right'caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Aerpe]]		[[Category: Aerpe]]
			[[Category: Large Structures]]
	[[Category: Bessho, Y]]		[[Category: Bessho, Y]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 08:41, 23 May 2018

2018-05-23T08:41:33Z

← Older revision		Revision as of 08:41, 23 May 2018
Line 1:		Line 1:

	==Crystal structure of archaeal transcription termination factor NusA==		==Crystal structure of archaeal transcription termination factor NusA==
	<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://pdbe.org/2cxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://pdbe.org/2cxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxc ProSAT], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/2cxc_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/2cxc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 22:29, 8 February 2016

2016-02-08T22:29:58Z

← Older revision		Revision as of 22:29, 8 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cxc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:58, 10 September 2015

2015-09-10T15:58:20Z

← Older revision		Revision as of 15:58, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aeropyrum_pernix Aeropyrum pernix~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpe Aerpe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://pdbe.org/2cxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2cxc" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Aeropyrum pernix~~]]		[[Category: Aerpe]]
	[[Category: Bessho, Y]]		[[Category: Bessho, Y]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 18:31, 15 January 2015

2015-01-15T18:31:23Z

← Older revision		Revision as of 18:31, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Aeropyrum pernix]]		[[Category: Aeropyrum pernix]]
	[[Category: Bessho, Y.]]		[[Category: Bessho, Y]]
	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]		[[Category: Structural genomic]]
	[[Category: Shibata, R.]]		[[Category: Shibata, R]]
	[[Category: Shirouzu, M.]]		[[Category: Shirouzu, M]]
	[[Category: Yokoyama, S.]]		[[Category: Yokoyama, S]]
	[[Category: Archaeal nusa]]		[[Category: Archaeal nusa]]
	[[Category: Kh domain]]		[[Category: Kh domain]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
	~~[[Category: Riken structural genomics/proteomics initiative]]~~
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
	~~[[Category: Structural genomic]]~~
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Transcription termination]]		[[Category: Transcription termination]]

OCA at 03:01, 30 September 2014

2014-09-30T03:01:34Z

← Older revision		Revision as of 03:01, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2cxc~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of archaeal transcription termination factor NusA==
			<StructureSection load='2cxc' size='340' side='right' caption='[[2cxc]], [[Resolution\|resolution]] 2.00Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXC FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxc RCSB], [http://www.ebi.ac.uk/pdbsum/2cxc PDBsum], [http://www.topsan.org/Proteins/RSGI/2cxc TOPSAN]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/2cxc_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The transcription factor NusA functions in transcriptional regulation involving termination in bacteria. A NusA homolog consisting of only the two KH domains is widely conserved in archaea, but its function remains unknown. We have found that Aeropyrum pernix NusA strongly binds to a certain CU-rich sequence near a termination signal. Our crystal structure of A. pernix NusA revealed that its spatial arrangement is quite similar to that of the KH domains of bacterial NusA. Thus, we consider archaeal NusA to have retained some functions of bacterial NusA, including the ssRNA-binding ability. Remarkable structural differences between archaeal and bacterial NusA exist at the interface with RNAP, in connection with the different NusA-binding sites around the termination signals. Transcriptional termination in archaea could differ from all of the known bacterial and eukaryal mechanisms, in terms of the combination of a bacterial factor and a eukaryal-type RNAP.

	~~{{STRUCTURE_2cxc\| PDB=2cxc \| SCENE= }}~~		Crystal structure and RNA-binding analysis of the archaeal transcription factor NusA.,Shibata R, Bessho Y, Shinkai A, Nishimoto M, Fusatomi E, Terada T, Shirouzu M, Yokoyama S Biochem Biophys Res Commun. 2007 Mar 30;355(1):122-8. Epub 2007 Jan 31. PMID:17288993<ref>PMID:17288993</ref>

	~~===Crystal structure~~ of ~~archaeal transcription termination factor NusA===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17288993}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2cxc]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Aeropyrum_pernix Aeropyrum pernix]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:017288993<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Aeropyrum pernix]]		[[Category: Aeropyrum pernix]]
	[[Category: Bessho, Y.]]		[[Category: Bessho, Y.]]

OCA: Protected "2cxc" [edit=sysop:move=sysop]

2013-01-06T12:11:53Z

Protected "2cxc" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:11, 6 January 2013
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OCA at 12:11, 6 January 2013

2013-01-06T12:11:50Z

← Older revision		Revision as of 12:11, 6 January 2013
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	[[Image:2cxc.png\|left\|200px]]		[[Image:2cxc.png\|left\|200px]]

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	{{STRUCTURE_2cxc\| PDB=2cxc \| SCENE= }}		{{STRUCTURE_2cxc\| PDB=2cxc \| SCENE= }}

	===Crystal structure of archaeal transcription termination factor NusA===		===Crystal structure of archaeal transcription termination factor NusA===


	~~<!--~~
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	{{ABSTRACT_PUBMED_17288993}}		{{ABSTRACT_PUBMED_17288993}}

	==About this Structure==		==About this Structure==
	~~2CXC~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA].		[[2cxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXC OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17288993~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017288993</ref><references group="xtra"/>
	[[Category: Aeropyrum pernix]]		[[Category: Aeropyrum pernix]]
	[[Category: Bessho, Y.]]		[[Category: Bessho, Y.]]
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	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
			[[Category: Transcription]]
	[[Category: Transcription termination]]		[[Category: Transcription termination]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:02:06 2009''~~