2d2e - Revision history

OCA at 13:45, 13 March 2024

2024-03-13T13:45:48Z

← Older revision		Revision as of 13:45, 13 March 2024
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	<StructureSection load='2d2e' size='340' side='right'caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2d2e' size='340' side='right'caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D2E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[2d2f\|2d2f]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [https://pdbe.org/2d2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [https://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2e ProSAT], [https://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [https://pdbe.org/2d2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [https://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2e ProSAT], [https://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q5SH92_THET8 Q5SH92_THET8]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d2e ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d2e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	SufC, a cytoplasmic ABC-ATPase, is one of the most conserved Suf proteins. SufC forms a stable complex with SufB and SufD, and the SufBCD complex interacts with other Suf proteins in the Fe-S cluster assembly. We have determined the crystal structure of SufC from Thermus thermophilus HB8 in nucleotide-free and ADP-Mg-bound states at 1.7A and 1.9A resolution, respectively. The overall architecture of the SufC structure is similar to other ABC ATPases structures, but there are several specific motifs in SufC. Three residues following the end of the Walker B motif form a novel 3(10) helix which is not observed in other ABC ATPases. Due to the novel 3(10) helix, a conserved glutamate residue involved in ATP hydrolysis is flipped out. Although this unusual conformation is unfavorable for ATP hydrolysis, salt-bridges formed by conserved residues and a strong hydrogen-bonding network around the novel 3(10) helix suggest that the novel 3(10) helix of SufC is a rigid conserved motif. Compared to other ABC-ATPase structures, a significant displacement occurs at a linker region between the ABC alpha/beta domain and the alpha-helical domain. The linker conformation is stabilized by a hydrophobic interaction between conserved residues around the Q loop. The molecular surfaces of SufC and the C-terminal helices of SufD (PDB code: 1VH4) suggest that the unusual linker conformation conserved among SufC proteins is probably suitable for interacting with SufB and SufD.

	Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8.,Watanabe S, Kita A, Miki K J Mol Biol. 2005 Nov 11;353(5):1043-54. Epub 2005 Sep 23. PMID:16216272<ref>PMID:16216272</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 2d2e" style="background-color:#fffaf0;"></div>~~

	==See Also==		==See Also==
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Thet8~~]]		[[Category: Thermus thermophilus HB8]]
	[[Category: Kita, A]]		[[Category: Kita A]]
	[[Category: Miki, K]]		[[Category: Miki K]]
	~~[[Category: Structural genomic~~]]		[[Category: Watanabe S]]
	[[Category: Watanabe, S]]
	~~[[Category: 310-helix]]~~
	~~[[Category: Abc-atpase]]~~
	~~[[Category: Protein binding]]~~
	~~[[Category: Rsgi]]~~
	~~[[Category: Suf protein~~]]

OCA at 10:26, 8 December 2021

2021-12-08T10:26:04Z

← Older revision		Revision as of 10:26, 8 December 2021
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	<StructureSection load='2d2e' size='340' side='right'caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2d2e' size='340' side='right'caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2D2E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2d2f\|2d2f]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [~~http~~://pdbe.org/2d2e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2e ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [https://pdbe.org/2d2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [https://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2e ProSAT], [https://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:54, 4 March 2020

2020-03-04T07:54:28Z

← Older revision		Revision as of 07:54, 4 March 2020
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	==Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8==		==Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8==
	<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2d2e' size='340' side='right'caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Heat Shock ~~Proteins~~\|Heat Shock ~~Proteins~~]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Kita, A]]		[[Category: Kita, A]]

OCA at 06:46, 30 May 2018

2018-05-30T06:46:39Z

← Older revision		Revision as of 06:46, 30 May 2018
Line 1:		Line 1:

	==Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8==		==Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8==
	<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://pdbe.org/2d2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://pdbe.org/2d2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2d2e ProSAT], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2e_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2e_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d2e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	[[Category: Kita, A]]		[[Category: Kita, A]]
	[[Category: Miki, K]]		[[Category: Miki, K]]
			[[Category: Structural genomic]]
	[[Category: Watanabe, S]]		[[Category: Watanabe, S]]
	[[Category: 310-helix]]		[[Category: 310-helix]]
	[[Category: Abc-atpase]]		[[Category: Abc-atpase]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	~~[[Category: Structural genomic]]~~
	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Suf protein]]		[[Category: Suf protein]]

OCA at 07:12, 11 September 2015

2015-09-11T07:12:58Z

← Older revision		Revision as of 07:12, 11 September 2015
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	<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://pdbe.org/2d2e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2d2e" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Thermus thermophilus~~]]		[[Category: Thet8]]
	[[Category: Kita, A]]		[[Category: Kita, A]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 18:26, 15 January 2015

2015-01-15T18:26:09Z

← Older revision		Revision as of 18:26, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Kita, A.]]		[[Category: Kita, A]]
	[[Category: Miki, K.]]		[[Category: Miki, K]]
	[[Category: Watanabe, S.]]		[[Category: Watanabe, S]]
	[[Category: 310-helix]]		[[Category: 310-helix]]
	[[Category: Abc-atpase]]		[[Category: Abc-atpase]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: ~~Riken structural genomics/proteomics initiative~~]]		[[Category: Structural genomic]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
	~~[[Category: Structural genomic]]~~
	[[Category: Suf protein]]		[[Category: Suf protein]]

OCA at 04:15, 29 September 2014

2014-09-29T04:15:05Z

← Older revision		Revision as of 04:15, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2d2e~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8==
			<StructureSection load='2d2e' size='340' side='right' caption='[[2d2e]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D2E FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2d2f\|2d2f]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d2e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d2e RCSB], [http://www.ebi.ac.uk/pdbsum/2d2e PDBsum], [http://www.topsan.org/Proteins/RSGI/2d2e TOPSAN]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d2/2d2e_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			SufC, a cytoplasmic ABC-ATPase, is one of the most conserved Suf proteins. SufC forms a stable complex with SufB and SufD, and the SufBCD complex interacts with other Suf proteins in the Fe-S cluster assembly. We have determined the crystal structure of SufC from Thermus thermophilus HB8 in nucleotide-free and ADP-Mg-bound states at 1.7A and 1.9A resolution, respectively. The overall architecture of the SufC structure is similar to other ABC ATPases structures, but there are several specific motifs in SufC. Three residues following the end of the Walker B motif form a novel 3(10) helix which is not observed in other ABC ATPases. Due to the novel 3(10) helix, a conserved glutamate residue involved in ATP hydrolysis is flipped out. Although this unusual conformation is unfavorable for ATP hydrolysis, salt-bridges formed by conserved residues and a strong hydrogen-bonding network around the novel 3(10) helix suggest that the novel 3(10) helix of SufC is a rigid conserved motif. Compared to other ABC-ATPase structures, a significant displacement occurs at a linker region between the ABC alpha/beta domain and the alpha-helical domain. The linker conformation is stabilized by a hydrophobic interaction between conserved residues around the Q loop. The molecular surfaces of SufC and the C-terminal helices of SufD (PDB code: 1VH4) suggest that the unusual linker conformation conserved among SufC proteins is probably suitable for interacting with SufB and SufD.

	~~{{STRUCTURE_2d2e\| PDB=2d2e \| SCENE= }}~~		Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8.,Watanabe S, Kita A, Miki K J Mol Biol. 2005 Nov 11;353(5):1043-54. Epub 2005 Sep 23. PMID:16216272<ref>PMID:16216272</ref>

	~~===Crystal structure~~ of ~~atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16216272}}~~

	~~==About this Structure==~~
	~~[[2d2e]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2D2E OCA].~~

	==See Also==		==See Also==
	*[[Heat Shock Proteins\|Heat Shock Proteins]]		*[[Heat Shock Proteins\|Heat Shock Proteins]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:016216272<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Kita, A.]]		[[Category: Kita, A.]]

OCA at 17:00, 20 October 2012

2012-10-20T17:00:55Z

← Older revision		Revision as of 17:00, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2d2e]] is a 1 chain structure ~~of [[Heat Shock Proteins]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA].		[[2d2e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA].

	==See Also==		==See Also==

OCA at 23:33, 26 July 2012

2012-07-26T23:33:23Z

← Older revision		Revision as of 23:33, 26 July 2012
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	[[Image:2d2e.png\|left\|200px]]		[[Image:2d2e.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2d2e", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2d2e\| PDB=2d2e \| SCENE= }}		{{STRUCTURE_2d2e\| PDB=2d2e \| SCENE= }}

	===Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8===		===Crystal structure of atypical cytoplasmic ABC-ATPase SufC from Thermus thermophilus HB8===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16216272}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16216272 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_16216272}}		{{ABSTRACT_PUBMED_16216272}}

	==About this Structure==		==About this Structure==
	[[2d2e]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8~~ Thermus thermophilus ~~hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA].		[[2d2e]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2E OCA].

	==See Also==		==See Also==
	*[[Heat Shock Proteins]]		*[[Heat Shock Proteins\|Heat Shock Proteins]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16216272~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016216272</ref><references group="xtra"/>
	[[Category: Thermus thermophilus ~~hb8~~]]		[[Category: Thermus thermophilus]]
	[[Category: Kita, A.]]		[[Category: Kita, A.]]
	[[Category: Miki, K.]]		[[Category: Miki, K.]]

OCA: Protected "2d2e" [edit=sysop:move=sysop]

2010-12-26T23:17:01Z

Protected "2d2e" [edit=sysop:move=sysop]

← Older revision	Revision as of 23:17, 26 December 2010
(No difference)