2dde - Revision history

OCA at 09:04, 6 November 2024

2024-11-06T09:04:52Z

← Older revision		Revision as of 09:04, 6 November 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene>, <scene name='pdbligand=PRD_000195:Cinnamycin'>PRD_000195</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene>, <scene name='pdbligand=PRD_000195:Cinnamycin'>PRD_000195</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>

OCA at 13:05, 26 July 2023

2023-07-26T13:05:29Z

← Older revision		Revision as of 13:05, 26 July 2023
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	==Structure of cinnamycin complexed with lysophosphatidylethanolamine==		==Structure of cinnamycin complexed with lysophosphatidylethanolamine==
	<StructureSection load='2dde' size='340' side='right'caption='[[2dde~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>		<StructureSection load='2dde' size='340' side='right'caption='[[2dde]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene>, <scene name='pdbligand=PRD_000195:Cinnamycin'>PRD_000195</scene></td></tr>
	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td><~~td class~~=~~"sblockDat"><div style~~=~~'overflow: auto; max-height~~: ~~3em;~~'>~~[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]~~</~~div~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.		[https://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Streptomyces griseoverticillatus]]		[[Category: Streptomyces griseoverticillatus]]
	[[Category: Endo, S]]		[[Category: Endo S]]
	[[Category: Hosoda, K]]		[[Category: Hosoda K]]
	[[Category: Kohno, T]]		[[Category: Kohno T]]
	[[Category: Maeda, T]]		[[Category: Maeda T]]
	[[Category: Ohya, M]]		[[Category: Ohya M]]
	[[Category: Wakamatsu, K]]		[[Category: Wakamatsu K]]
	~~[[Category: Antibiotic]]~~
	~~[[Category: Antimicrobial]]~~
	~~[[Category: Antitumor]]~~
	~~[[Category: Immunopotentiator]]~~
	~~[[Category: Lanthionine]]~~
	~~[[Category: Lipid binding]]~~
	~~[[Category: Phosphatidylethanolamine]]~~
	~~[[Category: Thioester~~]]

OCA at 20:37, 20 October 2021

2021-10-20T20:37:39Z

← Older revision		Revision as of 20:37, 20 October 2021
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	<StructureSection load='2dde' size='340' side='right'caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2dde' size='340' side='right'caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DDE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [~~http~~://pdbe.org/2dde PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dde PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.		[[https://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:05, 6 November 2019

2019-11-06T07:05:53Z

← Older revision		Revision as of 07:05, 6 November 2019
Line 1:		Line 1:

	==Structure of cinnamycin complexed with lysophosphatidylethanolamine==		==Structure of cinnamycin complexed with lysophosphatidylethanolamine==
	<StructureSection load='2dde' size='340' side='right' caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2dde' size='340' side='right'caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DDE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DDE FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Streptomyces griseoverticillatus]]		[[Category: Streptomyces griseoverticillatus]]
	[[Category: Endo, S]]		[[Category: Endo, S]]

OCA at 06:56, 30 May 2018

2018-05-30T06:56:10Z

← Older revision		Revision as of 06:56, 30 May 2018
Line 1:		Line 1:

	==Structure of cinnamycin complexed with lysophosphatidylethanolamine==		==Structure of cinnamycin complexed with lysophosphatidylethanolamine==
	<StructureSection load='2dde' size='340' side='right' caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2dde' size='340' side='right' caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
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	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://pdbe.org/2dde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://pdbe.org/2dde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:26, 11 September 2015

2015-09-11T13:26:10Z

← Older revision		Revision as of 13:26, 11 September 2015
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	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://pdbe.org/2dde PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2dde" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:03, 25 December 2014

2014-12-25T17:03:13Z

← Older revision		Revision as of 17:03, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:33, 8 December 2014

2014-12-08T08:33:59Z

← Older revision		Revision as of 08:33, 8 December 2014
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	~~{{STRUCTURE_2dde~~\| ~~PDB~~=2dde \| ~~SCENE~~= }}		==Structure of cinnamycin complexed with lysophosphatidylethanolamine==
	===~~Structure of cinnamycin complexed with lysophosphatidylethanolamine~~===		<StructureSection load='2dde' size='340' side='right' caption='[[2dde]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	~~{{ABSTRACT_PUBMED_8882709}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DDE FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aj1\|1aj1]], [[1mqx\|1mqx]], [[1mqy\|1mqy]], [[1mqz\|1mqz]], [[1qow\|1qow]], [[1w9n\|1w9n]], [[1wco\|1wco]], [[2ktn\|2ktn]], [[2kto\|2kto]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [http://www.ebi.ac.uk/pdbsum/2dde PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The three-dimensional structure of a complex of cinnamycin, a 19-amino acid residue immunopotentiator peptide, and lysophosphatidylethanolamine was determined by 1H-NMR. The complex was cylindrical in shape, 11 A in diameter and 26 A in length, excluding the acyl chain of the phospholipid. The peptide had a hydrophobic pocket surrounded by residues Phe-7 through Ala(S)-14 to bind to the head group of the ligand. Fitting of the head group to the hydrophobic pocket was so good that other than a glycerophosphoethanolamine head group would be unable to fit the pocket. The goodness of the fitting is compatible with the strict specificity of ligand binding of the peptide.

	~~==Function==~~		Structure determination of an immunopotentiator peptide, cinnamycin, complexed with lysophosphatidylethanolamine by 1H-NMR1.,Hosoda K, Ohya M, Kohno T, Maeda T, Endo S, Wakamatsu K J Biochem. 1996 Feb;119(2):226-30. PMID:8882709<ref>PMID:8882709</ref>
	~~[[http://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor~~ of ~~the enzyme phospholipase A2~~, ~~and of the angiotensin~~-~~converting enzyme~~. ~~Shows inhibitory activities against herpes simplex virus and immunopotentiating activities~~. ~~Its antimicrobial activities are not very pronounced~~.

	~~==About this Structure==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[2dde]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA].~~		</div>
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:008882709</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Streptomyces griseoverticillatus]]		[[Category: Streptomyces griseoverticillatus]]
	[[Category: Endo, S.]]		[[Category: Endo, S]]
	[[Category: Hosoda, K.]]		[[Category: Hosoda, K]]
	[[Category: Kohno, T.]]		[[Category: Kohno, T]]
	[[Category: Maeda, T.]]		[[Category: Maeda, T]]
	[[Category: Ohya, M.]]		[[Category: Ohya, M]]
	[[Category: Wakamatsu, K.]]		[[Category: Wakamatsu, K]]
	[[Category: Antibiotic]]		[[Category: Antibiotic]]
	[[Category: Antimicrobial]]		[[Category: Antimicrobial]]

OCA at 08:52, 23 April 2014

2014-04-23T08:52:06Z

← Older revision		Revision as of 08:52, 23 April 2014
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	~~[[Image:2dde.png\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2dde", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2dde\| PDB=2dde \| SCENE= }}		{{STRUCTURE_2dde\| PDB=2dde \| SCENE= }}

	===Structure of cinnamycin complexed with lysophosphatidylethanolamine===		===Structure of cinnamycin complexed with lysophosphatidylethanolamine===
			{{ABSTRACT_PUBMED_8882709}}

			==Function==
	~~<!--~~		[[http://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV]] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced.
	~~The line below this paragraph, {{ABSTRACT_PUBMED_8882709}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov)~~, ~~where 8882709 is~~ the ~~PubMed ID number~~.
	~~-->~~
	~~{{ABSTRACT_PUBMED_8882709}}~~

	==About this Structure==		==About this Structure==
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	==Reference==		==Reference==
	<ref group="xtra">PMID:008882709</ref><references group="xtra"/>		<ref group="xtra">PMID:008882709</ref><references group="xtra"/><references/>
	[[Category: Streptomyces griseoverticillatus]]		[[Category: Streptomyces griseoverticillatus]]
	[[Category: Endo, S.]]		[[Category: Endo, S.]]

OCA: Protected "2dde" [edit=sysop:move=sysop]

2011-07-27T05:25:26Z

Protected "2dde" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:25, 27 July 2011
(No difference)