2dea - Revision history

OCA at 07:55, 30 October 2024

2024-10-30T07:55:18Z

← Older revision		Revision as of 07:55, 30 October 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dea_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dea_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 11:38, 22 May 2024

2024-05-22T11:38:06Z

← Older revision		Revision as of 11:38, 22 May 2024
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	<StructureSection load='2dea' size='340' side='right'caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>		<StructureSection load='2dea' size='340' side='right'caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.24Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]~~</~~div~~><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [https://pdbe.org/2dea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [https://www.ebi.ac.uk/pdbsum/2dea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dea ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [https://pdbe.org/2dea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [https://www.ebi.ac.uk/pdbsum/2dea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dea ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/AMPX_VIBPR AMPX_VIBPR]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Aeromonas proteolytica merkel et al. 1964]]~~
	~~[[Category: Bacterial leucyl aminopeptidase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Desmarais, W~~]]		[[Category: Vibrio proteolyticus]]
	[[Category: ~~Petsko, G A~~]]		[[Category: Desmarais W]]
	[[Category: ~~Ringe, D~~]]		[[Category: Petsko GA]]
	[[Category: ~~Aminopeptidase]]~~		[[Category: Ringe D]]
	~~[[Category: Bimetalloenzyme]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Low ph]]~~
	~~[[Category: Metalloenzyme]]~~
	~~[[Category: Zinc enzyme~~]]

OCA at 10:30, 8 December 2021

2021-12-08T10:30:36Z

← Older revision		Revision as of 10:30, 8 December 2021
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	<StructureSection load='2dea' size='340' side='right'caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>		<StructureSection load='2dea' size='340' side='right'caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DEA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [~~http~~://pdbe.org/2dea PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dea PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dea ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [https://pdbe.org/2dea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [https://www.ebi.ac.uk/pdbsum/2dea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dea ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:35, 4 March 2020

2020-03-04T07:35:41Z

← Older revision		Revision as of 07:35, 4 March 2020
Line 1:		Line 1:

	==Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7==		==Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7==
	<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>		<StructureSection load='2dea' size='340' side='right'caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Aminopeptidase\|Aminopeptidase]]		*[[Aminopeptidase 3D structures\|Aminopeptidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	[[Category: Aeromonas proteolytica merkel et al. 1964]]		[[Category: Aeromonas proteolytica merkel et al. 1964]]
	[[Category: Bacterial leucyl aminopeptidase]]		[[Category: Bacterial leucyl aminopeptidase]]
			[[Category: Large Structures]]
	[[Category: Desmarais, W]]		[[Category: Desmarais, W]]
	[[Category: Petsko, G A]]		[[Category: Petsko, G A]]

OCA at 06:14, 30 May 2018

2018-05-30T06:14:57Z

← Older revision		Revision as of 06:14, 30 May 2018
Line 1:		Line 1:

	==Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7==		==Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7==
	<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>		<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://pdbe.org/2dea PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://pdbe.org/2dea PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dea ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dea_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dea_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:03, 10 February 2016

2016-02-10T01:03:09Z

← Older revision		Revision as of 01:03, 10 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dea ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:49, 11 September 2015

2015-09-11T03:49:07Z

← Older revision		Revision as of 03:49, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>		<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Vibrio_proteolyticus Vibrio proteolyticus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aeromonas_proteolytica"_merkel_et_al._1964 "aeromonas proteolytica" merkel et al. 1964]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://pdbe.org/2dea PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2dea" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Aeromonas proteolytica merkel et al. 1964]]
	[[Category: Bacterial leucyl aminopeptidase]]		[[Category: Bacterial leucyl aminopeptidase]]
	~~[[Category: Vibrio proteolyticus]]~~
	[[Category: Desmarais, W]]		[[Category: Desmarais, W]]
	[[Category: Petsko, G A]]		[[Category: Petsko, G A]]

OCA at 17:33, 15 January 2015

2015-01-15T17:33:43Z

← Older revision		Revision as of 17:33, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Bacterial leucyl aminopeptidase]]		[[Category: Bacterial leucyl aminopeptidase]]
	[[Category: Vibrio proteolyticus]]		[[Category: Vibrio proteolyticus]]
	[[Category: Desmarais, W.]]		[[Category: Desmarais, W]]
	[[Category: Petsko, G A.]]		[[Category: Petsko, G A]]
	[[Category: Ringe, D.]]		[[Category: Ringe, D]]
	[[Category: Aminopeptidase]]		[[Category: Aminopeptidase]]
	[[Category: Bimetalloenzyme]]		[[Category: Bimetalloenzyme]]

OCA at 06:03, 29 September 2014

2014-09-29T06:03:32Z

← Older revision		Revision as of 06:03, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2dea~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7==
			<StructureSection load='2dea' size='340' side='right' caption='[[2dea]], [[Resolution\|resolution]] 1.24Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DEA FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1lok\|1lok]], [[1rtq\|1rtq]], [[1ft7\|1ft7]], [[1txr\|1txr]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bacterial_leucyl_aminopeptidase Bacterial leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.10 3.4.11.10] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dea OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dea RCSB], [http://www.ebi.ac.uk/pdbsum/2dea PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dea_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The aminopeptidase from Aeromonas proteolytica (AAP) contains two zinc ions in the active site and catalyzes the degradation of peptides. Herein we report the crystal structures of AAP at 0.95-A resolution at neutral pH and at 1.24-A resolution at low pH. The combination of these structures allowed the precise modeling of atomic positions, the identification of the metal bridging oxygen species, and insight into the physical properties of the metal ions. On the basis of these structures, a new putative catalytic mechanism is proposed for AAP that is likely relevant to all binuclear metalloproteases.

	~~{{STRUCTURE_2dea\| PDB=2dea \| SCENE= }}~~		The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica.,Desmarais W, Bienvenue DL, Bzymek KP, Petsko GA, Ringe D, Holz RC J Biol Inorg Chem. 2006 Jun;11(4):398-408. Epub 2006 Apr 5. PMID:16596389<ref>PMID:16596389</ref>

	~~===Crystal Structure~~ of the ~~Aminopeptidase~~ of ~~Aeromonas proteolytica at pH 4~~.~~7===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16596389}}~~

	~~==About this Structure==~~
	~~[[2dea]] is a 1 chain structure with sequence from [http:/~~/~~en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA].~~

	==See Also==		==See Also==
	*[[Aminopeptidase\|Aminopeptidase]]		*[[Aminopeptidase\|Aminopeptidase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:016596389<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Bacterial leucyl aminopeptidase]]		[[Category: Bacterial leucyl aminopeptidase]]
	[[Category: Vibrio proteolyticus]]		[[Category: Vibrio proteolyticus]]

OCA at 15:45, 20 October 2012

2012-10-20T15:45:52Z

← Older revision		Revision as of 15:45, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2dea]] is a 1 chain structure ~~of [[Aminopeptidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA].		[[2dea]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_proteolyticus Vibrio proteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEA OCA].

	==See Also==		==See Also==