2dpf - Revision history

OCA at 05:10, 17 October 2024

2024-10-17T05:10:21Z

← Older revision		Revision as of 05:10, 17 October 2024
Line 15:		Line 15:
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpf_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 08:28, 25 October 2023

2023-10-25T08:28:02Z

← Older revision		Revision as of 08:28, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2dpf' size='340' side='right'caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2dpf' size='340' side='right'caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Curculigo_latifolia Curculigo~~ latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Molineria_latifolia Molineria latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [https://pdbe.org/2dpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [https://www.ebi.ac.uk/pdbsum/2dpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [https://pdbe.org/2dpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [https://www.ebi.ac.uk/pdbsum/2dpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/~~CURC1_CURLA CURC1_CURLA]~~] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.		[https://www.uniprot.org/uniprot/CURC1_MOLLA CURC1_MOLLA] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Curculigo latifolia]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Amemiya, E]]		[[Category: Molineria latifolia]]
	[[Category: Kashiwagi, T]]		[[Category: Amemiya E]]
	[[Category: Kato, K]]		[[Category: Kashiwagi T]]
	[[Category: Kawai, M]]		[[Category: Kato K]]
	[[Category: Kurimoto, E]]		[[Category: Kawai M]]
	[[Category: Nirasawa, S]]		[[Category: Kurimoto E]]
	[[Category: Shimba, N]]		[[Category: Nirasawa S]]
	[[Category: Suzuki, E]]		[[Category: Shimba N]]
	[[Category: Suzuki, M]]		[[Category: Suzuki E]]
	[[Category: Xu, N]]		[[Category: Suzuki M]]
	[[Category: Yamaguchi, Y]]		[[Category: Xu N]]
	~~[[Category: Plant protein]]~~		[[Category: Yamaguchi Y]]
	~~[[Category: Sweet taste]]~~
	~~[[Category: Taste modifying~~]]

OCA at 10:33, 8 December 2021

2021-12-08T10:33:51Z

← Older revision		Revision as of 10:33, 8 December 2021
Line 3:		Line 3:
	<StructureSection load='2dpf' size='340' side='right'caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2dpf' size='340' side='right'caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Curculigo_latifolia Curculigo latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Curculigo_latifolia Curculigo latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [~~http~~://pdbe.org/2dpf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dpf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [https://pdbe.org/2dpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [https://www.ebi.ac.uk/pdbsum/2dpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CURC1_CURLA CURC1_CURLA]] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.		[[https://www.uniprot.org/uniprot/CURC1_CURLA CURC1_CURLA]] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:42, 4 March 2020

2020-03-04T07:42:26Z

← Older revision		Revision as of 07:42, 4 March 2020
Line 1:		Line 1:

	==Crystal Structure of curculin1 homodimer==		==Crystal Structure of curculin1 homodimer==
	<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2dpf' size='340' side='right'caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Curculigo_latifolia Curculigo latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Curculigo_latifolia Curculigo latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Curculigo latifolia]]		[[Category: Curculigo latifolia]]
			[[Category: Large Structures]]
	[[Category: Amemiya, E]]		[[Category: Amemiya, E]]
	[[Category: Kashiwagi, T]]		[[Category: Kashiwagi, T]]

OCA at 06:25, 30 May 2018

2018-05-30T06:25:04Z

← Older revision		Revision as of 06:25, 30 May 2018
Line 1:		Line 1:

	==Crystal Structure of curculin1 homodimer==		==Crystal Structure of curculin1 homodimer==
	<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Curla Curla~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Curculigo_latifolia Curculigo latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://pdbe.org/2dpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://pdbe.org/2dpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dpf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpf_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dpf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Curla~~]]		[[Category: Curculigo latifolia]]
	[[Category: Amemiya, E]]		[[Category: Amemiya, E]]
	[[Category: Kashiwagi, T]]		[[Category: Kashiwagi, T]]

OCA at 17:34, 11 September 2015

2015-09-11T17:34:14Z

← Older revision		Revision as of 17:34, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Molineria_latifolia Molineria latifolia~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Curla Curla]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://pdbe.org/2dpf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~CURC_CURLA CURC_CURLA~~]] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.		[[http://www.uniprot.org/uniprot/CURC1_CURLA CURC1_CURLA]] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2dpf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Molineria latifolia~~]]		[[Category: Curla]]
	[[Category: Amemiya, E]]		[[Category: Amemiya, E]]
	[[Category: Kashiwagi, T]]		[[Category: Kashiwagi, T]]

OCA at 19:40, 25 December 2014

2014-12-25T19:40:17Z

← Older revision		Revision as of 19:40, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Molineria_latifolia Molineria latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Molineria_latifolia Molineria latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CURC_CURLA CURC_CURLA]] Taste-modifying protein; sweet-tasting. After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Molineria latifolia]]		[[Category: Molineria latifolia]]
	[[Category: Amemiya, E.]]		[[Category: Amemiya, E]]
	[[Category: Kashiwagi, T.]]		[[Category: Kashiwagi, T]]
	[[Category: Kato, K.]]		[[Category: Kato, K]]
	[[Category: Kawai, M.]]		[[Category: Kawai, M]]
	[[Category: Kurimoto, E.]]		[[Category: Kurimoto, E]]
	[[Category: Nirasawa, S.]]		[[Category: Nirasawa, S]]
	[[Category: Shimba, N.]]		[[Category: Shimba, N]]
	[[Category: Suzuki, E.]]		[[Category: Suzuki, E]]
	[[Category: Suzuki, M.]]		[[Category: Suzuki, M]]
	[[Category: Xu, N.]]		[[Category: Xu, N]]
	[[Category: Yamaguchi, Y.]]		[[Category: Yamaguchi, Y]]
	[[Category: Plant protein]]		[[Category: Plant protein]]
	[[Category: Sweet taste]]		[[Category: Sweet taste]]
	[[Category: Taste modifying]]		[[Category: Taste modifying]]

OCA at 00:57, 30 September 2014

2014-09-30T00:57:40Z

← Older revision		Revision as of 00:57, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2dpf~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure of curculin1 homodimer==
			<StructureSection load='2dpf' size='340' side='right' caption='[[2dpf]], [[Resolution\|resolution]] 1.50Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Molineria_latifolia Molineria latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DPF FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dpf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dpf RCSB], [http://www.ebi.ac.uk/pdbsum/2dpf PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/2dpf_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Curculin isolated from Curculigo latifolia, a plant grown in Malaysia, has an intriguing property of modifying sour taste into sweet taste. In addition to this taste-modifying activity, curculin itself elicits a sweet taste. Although these activities have been attributed to the heterodimeric isoform and not homodimers of curculin, the underlying mechanisms for the dual action of this protein have been largely unknown. To identify critical sites for these activities, we performed a mutational and structural study of recombinant curculin. Based on the comparison of crystal structures of curculin homo- and heterodimers, a series of mutants was designed and subjected to tasting assays. Mapping of amino acid residues on the three-dimensional structure according to their mutational effects revealed that the curculin heterodimer exhibits sweet-tasting and taste-modifying activities through its partially overlapping but distinct molecular surfaces. These findings suggest that the two activities of the curculin heterodimer are expressed through its two different modes of interactions with the T1R2-T1R3 heterodimeric sweet taste receptor.

	~~{{STRUCTURE_2dpf\| PDB=2dpf \| SCENE= }}~~		Curculin exhibits sweet-tasting and taste-modifying activities through its distinct molecular surfaces.,Kurimoto E, Suzuki M, Amemiya E, Yamaguchi Y, Nirasawa S, Shimba N, Xu N, Kashiwagi T, Kawai M, Suzuki E, Kato K J Biol Chem. 2007 Nov 16;282(46):33252-6. Epub 2007 Sep 25. PMID:17895249<ref>PMID:17895249</ref>

	~~===Crystal Structure~~ of ~~curculin1 homodimer===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17895249}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2dpf]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Molineria_latifolia Molineria latifolia]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:017895249<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Molineria latifolia]]		[[Category: Molineria latifolia]]
	[[Category: Amemiya, E.]]		[[Category: Amemiya, E.]]

OCA: Protected "2dpf" [edit=sysop:move=sysop]

2013-01-06T10:15:53Z

Protected "2dpf" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:15, 6 January 2013
(No difference)

OCA at 10:15, 6 January 2013

2013-01-06T10:15:49Z

← Older revision		Revision as of 10:15, 6 January 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2dpf.png\|left\|200px]]		[[Image:2dpf.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2dpf", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2dpf\| PDB=2dpf \| SCENE= }}		{{STRUCTURE_2dpf\| PDB=2dpf \| SCENE= }}

	===Crystal Structure of curculin1 homodimer===		===Crystal Structure of curculin1 homodimer===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17895249}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17895249 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_17895249}}		{{ABSTRACT_PUBMED_17895249}}

	==About this Structure==		==About this Structure==
	~~2DPF~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/~~Curculigo_latifolia Curculigo~~ latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA].		[[2dpf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Molineria_latifolia Molineria latifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DPF OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17895249~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017895249</ref><references group="xtra"/>
	[[Category: ~~Curculigo~~ latifolia]]		[[Category: Molineria latifolia]]
	[[Category: Amemiya, E.]]		[[Category: Amemiya, E.]]
	[[Category: Kashiwagi, T.]]		[[Category: Kashiwagi, T.]]
Line 39:		Line 27:
	[[Category: Sweet taste]]		[[Category: Sweet taste]]
	[[Category: Taste modifying]]		[[Category: Taste modifying]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:50:31 2009''~~