2dxa - Revision history

OCA at 08:31, 25 October 2023

2023-10-25T08:31:37Z

← Older revision		Revision as of 08:31, 25 October 2023
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	<StructureSection load='2dxa' size='340' side='right'caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='2dxa' size='340' side='right'caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.58Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [https://pdbe.org/2dxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [https://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxa ProSAT], [https://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [https://pdbe.org/2dxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [https://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxa ProSAT], [https://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/YBAK_ECOLI YBAK_ECOLI]] Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).<ref>PMID:15886196</ref> <ref>PMID:23185990</ref>		[https://www.uniprot.org/uniprot/YBAK_ECOLI YBAK_ECOLI] Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).<ref>PMID:15886196</ref> <ref>PMID:23185990</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kato-Murayama, M]]		[[Category: Kato-Murayama M]]
	[[Category: Murayama, K]]		[[Category: Murayama K]]
	~~[[Category: Structural genomic~~]]		[[Category: Shirouzu M]]
	[[Category: Shirouzu, M]]		[[Category: Terada T]]
	[[Category: Terada, T]]		[[Category: Yokoyama S]]
	[[Category: Yokoyama, S]]
	~~[[Category: National project on protein structural and functional analyse]]~~
	~~[[Category: Nppsfa]]~~
	~~[[Category: Prolyl-trna synthetase]]~~
	~~[[Category: Rsgi]]~~
	~~[[Category: Trans-editing domain]]~~
	~~[[Category: Translation~~]]

OCA at 17:18, 15 December 2021

2021-12-15T17:18:15Z

← Older revision		Revision as of 17:18, 15 December 2021
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	<StructureSection load='2dxa' size='340' side='right'caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='2dxa' size='340' side='right'caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [~~http~~://pdbe.org/2dxa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxa ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [https://pdbe.org/2dxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [https://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxa ProSAT], [https://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/YBAK_ECOLI YBAK_ECOLI]] Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).<ref>PMID:15886196</ref> <ref>PMID:23185990</ref>		[[https://www.uniprot.org/uniprot/YBAK_ECOLI YBAK_ECOLI]] Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).<ref>PMID:15886196</ref> <ref>PMID:23185990</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:23, 11 March 2020

2020-03-11T08:23:18Z

← Older revision		Revision as of 08:23, 11 March 2020
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	==Crystal structure of trans editing enzyme ProX from E.coli==		==Crystal structure of trans editing enzyme ProX from E.coli==
	<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='2dxa' size='340' side='right'caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Kato-Murayama, M]]		[[Category: Kato-Murayama, M]]
	[[Category: Murayama, K]]		[[Category: Murayama, K]]

OCA at 06:49, 6 June 2018

2018-06-06T06:49:01Z

← Older revision		Revision as of 06:49, 6 June 2018
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	==Crystal structure of trans editing enzyme ProX from E.coli==		==Crystal structure of trans editing enzyme ProX from E.coli==
	<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://pdbe.org/2dxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://pdbe.org/2dxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dxa ProSAT], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dxa_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dxa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dxa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	== References ==		== References ==

OCA at 23:03, 11 September 2015

2015-09-11T23:03:41Z

← Older revision		Revision as of 23:03, 11 September 2015
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	<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>		<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://pdbe.org/2dxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Kato-Murayama, M]]		[[Category: Kato-Murayama, M]]
	[[Category: Murayama, K]]		[[Category: Murayama, K]]

OCA at 20:37, 25 December 2014

2014-12-25T20:37:18Z

← Older revision		Revision as of 20:37, 25 December 2014
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/YBAK_ECOLI YBAK_ECOLI]] Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro).<ref>PMID:15886196</ref> <ref>PMID:23185990</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kato-Murayama, M.]]		[[Category: Kato-Murayama, M]]
	[[Category: Murayama, K.]]		[[Category: Murayama, K]]
	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]		[[Category: Structural genomic]]
	[[Category: Shirouzu, M.]]		[[Category: Shirouzu, M]]
	[[Category: Terada, T.]]		[[Category: Terada, T]]
	[[Category: Yokoyama, S.]]		[[Category: Yokoyama, S]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
	[[Category: Prolyl-trna synthetase]]		[[Category: Prolyl-trna synthetase]]
	~~[[Category: Riken structural genomics/proteomics initiative]]~~
	[[Category: Rsgi]]		[[Category: Rsgi]]
	~~[[Category: Structural genomic]]~~
	[[Category: Trans-editing domain]]		[[Category: Trans-editing domain]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 02:38, 30 September 2014

2014-09-30T02:38:12Z

← Older revision		Revision as of 02:38, 30 September 2014
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	~~[[Image:2dxa.png\|left\|200px]]~~		==Crystal structure of trans editing enzyme ProX from E.coli==
			<StructureSection load='2dxa' size='340' side='right' caption='[[2dxa]], [[Resolution\|resolution]] 1.58Å' scene=''>
	~~{{STRUCTURE_2dxa\| PDB=2dxa \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DXA FirstGlance]. <br>
	===Crystal structure of trans editing enzyme ProX from E.coli===		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
			<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dxa RCSB], [http://www.ebi.ac.uk/pdbsum/2dxa PDBsum], [http://www.topsan.org/Proteins/RSGI/2dxa TOPSAN]</span></td></tr>
	==~~About this Structure~~==		<table>
	[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA].		== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dxa_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kato-Murayama, M.]]		[[Category: Kato-Murayama, M.]]

OCA: Protected "2dxa" [edit=sysop:move=sysop]

2013-01-06T11:50:57Z

Protected "2dxa" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:50, 6 January 2013
(No difference)

OCA at 11:50, 6 January 2013

2013-01-06T11:50:54Z

← Older revision		Revision as of 11:50, 6 January 2013
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	~~{{Seed}}~~
	[[Image:2dxa.png\|left\|200px]]		[[Image:2dxa.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2dxa", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2dxa\| PDB=2dxa \| SCENE= }}		{{STRUCTURE_2dxa\| PDB=2dxa \| SCENE= }}

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	==About this Structure==		==About this Structure==
	~~2DXA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA].		[[2dxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kato-Murayama, M.]]		[[Category: Kato-Murayama, M.]]
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	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Trans-editing domain]]		[[Category: Trans-editing domain]]
			[[Category: Translation]]
	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Sun Nov 16 13:58:50 2008''~~

OCA at 11:58, 16 November 2008

2008-11-16T11:58:52Z

← Older revision		Revision as of 11:58, 16 November 2008
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	==About this Structure==		==About this Structure==
	2DXA is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA].		2DXA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DXA OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	~~[[Category: Single protein]]~~
	[[Category: Kato-Murayama, M.]]		[[Category: Kato-Murayama, M.]]
	[[Category: Murayama, K.]]		[[Category: Murayama, K.]]
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	[[Category: Trans-editing domain]]		[[Category: Trans-editing domain]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~Sep 28 20~~:58:06 2008''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 13:58:50 2008''