2dyn - Revision history

OCA at 09:19, 14 February 2024

2024-02-14T09:19:10Z

← Older revision		Revision as of 09:19, 14 February 2024
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	<StructureSection load='2dyn' size='340' side='right'caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2dyn' size='340' side='right'caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [https://pdbe.org/2dyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [https://www.ebi.ac.uk/pdbsum/2dyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyn ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [https://pdbe.org/2dyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [https://www.ebi.ac.uk/pdbsum/2dyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.		[https://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyn ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The pleckstrin homology (PH) domain is a conserved module present in many signal transducing and cytoskeletal proteins. Here we report the 2.8 A crystal structure of the PH domain from dynamin. This domain consists of seven beta-strands forming two roughly orthogonal antiparallel beta-sheets terminating with an amphipathic alpha-helix. The structure also reveals a non-covalent dimeric association of the PH domain and a hydrophobic pocket surrounded by a charged rim. The dynamin PH domain structure is discussed in relation to its potential role in mediating interactions between proteins.

	Crystal structure of the pleckstrin homology domain from dynamin.,Timm D, Salim K, Gout I, Guruprasad L, Waterfield M, Blundell T Nat Struct Biol. 1994 Nov;1(11):782-8. PMID:7634088<ref>PMID:7634088</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>~~
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Timm~~, D E]]~~		[[Category: Timm DE]]
	~~[[Category: Motor protein]]~~
	~~[[Category: Phospholipid binding]]~~
	~~[[Category: Protein binding]]~~
	~~[[Category: Signal transduction~~]]

OCA at 17:18, 15 December 2021

2021-12-15T17:18:36Z

← Older revision		Revision as of 17:18, 15 December 2021
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	<StructureSection load='2dyn' size='340' side='right'caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2dyn' size='340' side='right'caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [~~http~~://pdbe.org/2dyn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dyn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyn ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [https://pdbe.org/2dyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [https://www.ebi.ac.uk/pdbsum/2dyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.		[[https://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</div>		</div>
	<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Dynamin 3D structures\|Dynamin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:23, 11 March 2020

2020-03-11T08:23:51Z

← Older revision		Revision as of 08:23, 11 March 2020
Line 1:		Line 1:

	==DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)==		==DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)==
	<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2dyn' size='340' side='right'caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Dynamin 3D structures\|Dynamin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Timm, D E]]		[[Category: Timm, D E]]
	[[Category: Motor protein]]		[[Category: Motor protein]]

OCA at 06:54, 6 June 2018

2018-06-06T06:54:58Z

← Older revision		Revision as of 06:54, 6 June 2018
Line 1:		Line 1:

	==DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)==		==DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)==
	<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://pdbe.org/2dyn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://pdbe.org/2dyn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyn_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:14, 7 February 2016

2016-02-07T13:14:22Z

← Older revision		Revision as of 13:14, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:47, 10 September 2015

2015-09-10T01:47:45Z

← Older revision		Revision as of 01:47, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://pdbe.org/2dyn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2dyn" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Timm, D E]]		[[Category: Timm, D E]]
	[[Category: Motor protein]]		[[Category: Motor protein]]

OCA at 15:20, 24 December 2014

2014-12-24T15:20:41Z

← Older revision		Revision as of 15:20, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/DYN1_HUMAN DYN1_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Timm, D E.]]		[[Category: Timm, D E]]
	[[Category: Motor protein]]		[[Category: Motor protein]]
	[[Category: Phospholipid binding]]		[[Category: Phospholipid binding]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Signal transduction]]		[[Category: Signal transduction]]

OCA at 01:06, 30 September 2014

2014-09-30T01:06:12Z

← Older revision		Revision as of 01:06, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2dyn~~.~~png~~\|~~left~~\|~~200px~~]]		==DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)==
			<StructureSection load='2dyn' size='340' side='right' caption='[[2dyn]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DYN FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dyn RCSB], [http://www.ebi.ac.uk/pdbsum/2dyn PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyn_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The pleckstrin homology (PH) domain is a conserved module present in many signal transducing and cytoskeletal proteins. Here we report the 2.8 A crystal structure of the PH domain from dynamin. This domain consists of seven beta-strands forming two roughly orthogonal antiparallel beta-sheets terminating with an amphipathic alpha-helix. The structure also reveals a non-covalent dimeric association of the PH domain and a hydrophobic pocket surrounded by a charged rim. The dynamin PH domain structure is discussed in relation to its potential role in mediating interactions between proteins.

	~~{{STRUCTURE_2dyn\| PDB=2dyn \| SCENE= }}~~		Crystal structure of the pleckstrin homology domain from dynamin.,Timm D, Salim K, Gout I, Guruprasad L, Waterfield M, Blundell T Nat Struct Biol. 1994 Nov;1(11):782-8. PMID:7634088<ref>PMID:7634088</ref>

	~~===DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_7634088}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2dyn]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:007634088<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Timm, D E.]]		[[Category: Timm, D E.]]

OCA: Protected "2dyn" [edit=sysop:move=sysop]

2013-01-06T10:22:46Z

Protected "2dyn" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:22, 6 January 2013
(No difference)

OCA at 10:22, 6 January 2013

2013-01-06T10:22:44Z

← Older revision		Revision as of 10:22, 6 January 2013
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	[[Image:2dyn.png\|left\|200px]]		[[Image:2dyn.png\|left\|200px]]

	~~<!--~~
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	{{STRUCTURE_2dyn\| PDB=2dyn \| SCENE= }}		{{STRUCTURE_2dyn\| PDB=2dyn \| SCENE= }}

	===DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)===		===DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH)===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_7634088}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_7634088}}		{{ABSTRACT_PUBMED_7634088}}

	==About this Structure==		==About this Structure==
	~~2DYN~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA].		[[2dyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYN OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~7634088~~</ref><references group="xtra"/>		<ref group="xtra">PMID:007634088</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Timm, D E.]]		[[Category: Timm, D E.]]
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	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Signal transduction]]		[[Category: Signal transduction]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:02:42 2009''~~