2ebs - Revision history

OCA at 08:38, 25 October 2023

2023-10-25T08:38:29Z

← Older revision		Revision as of 08:38, 25 October 2023
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	<StructureSection load='2ebs' size='340' side='right'caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2ebs' size='340' side='right'caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Geos1 Geos1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geotrichum_sp._M128 Geotrichum sp. M128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BGC:BETA-D~~-~~GLUCOSE'>BGC</scene>~~, ~~<scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1sqj\|1sqj]]~~</~~div~~><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [https://pdbe.org/2ebs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [https://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebs ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [https://pdbe.org/2ebs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [https://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebs ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/CBHRE_GEOS1 CBHRE_GEOS1]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Geos1~~]]		[[Category: Geotrichum sp. M128]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]~~		[[Category: Hiyoshi A]]
	[[Category: Hiyoshi, A]]		[[Category: Kondo H]]
	[[Category: Kondo, H]]		[[Category: Miyazaki K]]
	[[Category: Miyazaki, K]]		[[Category: Noro N]]
	[[Category: Noro, N]]		[[Category: Sugimoto H]]
	~~[[Category: Structural genomic~~]]		[[Category: Yaoi K]]
	[[Category: Sugimoto, H]]
	[[Category: Yaoi, K]]
	~~[[Category: Beta-propeller]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: National project on protein structural and functional analyse]]~~
	~~[[Category: Nppsfa]]~~
	~~[[Category: Rsgi~~]]

OCA at 06:54, 10 November 2021

2021-11-10T06:54:58Z

← Older revision		Revision as of 06:54, 10 November 2021
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	<StructureSection load='2ebs' size='340' side='right'caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2ebs' size='340' side='right'caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Geos1 Geos1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2EBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geos1 Geos1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sqj\|1sqj]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [~~http~~://pdbe.org/2ebs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebs ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [https://pdbe.org/2ebs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [https://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebs ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:30, 11 March 2020

2020-03-11T08:30:56Z

← Older revision		Revision as of 08:30, 11 March 2020
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	==Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide==		==Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide==
	<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2ebs' size='340' side='right'caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geos1 Geos1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geos1 Geos1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Cellobiohydrolase\|Cellobiohydrolase]]		*[[Cellobiohydrolase 3D structures\|Cellobiohydrolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Geos1]]		[[Category: Geos1]]
			[[Category: Large Structures]]
	[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]		[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]
	[[Category: Hiyoshi, A]]		[[Category: Hiyoshi, A]]

OCA at 06:48, 6 June 2018

2018-06-06T06:48:05Z

← Older revision		Revision as of 06:48, 6 June 2018
Line 1:		Line 1:

	==Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide==		==Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide==
	<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://pdbe.org/2ebs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://pdbe.org/2ebs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebs ProSAT], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebs_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:10, 9 February 2016

2016-02-09T11:10:27Z

← Older revision		Revision as of 11:10, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:43, 10 September 2015

2015-09-10T21:43:53Z

← Older revision		Revision as of 21:43, 10 September 2015
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	<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Geotrichum_sp._m128 Geotrichum sp. m128~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geos1 Geos1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://pdbe.org/2ebs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ebs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Geotrichum sp. m128~~]]		[[Category: Geos1]]
	[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]		[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]
	[[Category: Hiyoshi, A]]		[[Category: Hiyoshi, A]]

OCA at 17:54, 15 January 2015

2015-01-15T17:54:07Z

← Older revision		Revision as of 17:54, 15 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Geotrichum sp. m128]]		[[Category: Geotrichum sp. m128]]
	[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]		[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]
	[[Category: Hiyoshi, A.]]		[[Category: Hiyoshi, A]]
	[[Category: Kondo, H.]]		[[Category: Kondo, H]]
	[[Category: Miyazaki, K.]]		[[Category: Miyazaki, K]]
	[[Category: Noro, N.]]		[[Category: Noro, N]]
	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]		[[Category: Structural genomic]]
	[[Category: Sugimoto, H.]]		[[Category: Sugimoto, H]]
	[[Category: Yaoi, K.]]		[[Category: Yaoi, K]]
	[[Category: Beta-propeller]]		[[Category: Beta-propeller]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
	~~[[Category: Riken structural genomics/proteomics initiative]]~~
	[[Category: Rsgi]]		[[Category: Rsgi]]
	~~[[Category: Structural genomic]]~~

OCA at 09:51, 29 September 2014

2014-09-29T09:51:49Z

← Older revision		Revision as of 09:51, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2ebs~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide==
			<StructureSection load='2ebs' size='340' side='right' caption='[[2ebs]], [[Resolution\|resolution]] 2.40Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBS FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=XYS:XYLOPYRANOSE'>XYS</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1sqj\|1sqj]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oligoxyloglucan_reducing-end-specific_cellobiohydrolase Oligoxyloglucan reducing-end-specific cellobiohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.150 3.2.1.150] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ebs RCSB], [http://www.ebi.ac.uk/pdbsum/2ebs PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebs TOPSAN]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebs_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Oligoxyloglucan reducing end-specific cellobiohydrolase (OXG-RCBH) is a unique exo-beta-1,4-glucanase that belongs to glycoside hydrolase family 74. The enzyme recognizes the reducing end of xyloglucan oligosaccharides and releases two glucosyl residue segments from the reducing end of the main chain. Previously, we reported that OXG-RCBH consists of two seven-bladed beta-propeller domains. There is a large cleft between the two domains, and a unique loop encloses one side of the active site cleft. Here, we report the X-ray crystal structure of the OXG-RCBH-substrate complex determined to a resolution of 2.4 A. The substrate bound to the cleft, and its reducing end was arranged near the loop region that is believed to impart OXG-RCBH with its activity. We constructed a deletion mutant of the loop region and conducted a detailed analysis. A deletion mutant of the loop region showed endo-activity with altered substrate recognition. More specifically, cleavage occurred randomly instead of at specific sites, most likely due to the misalignment of the substrate within the subsite. We believe that the loop imparts unique substrate specificity with exo-mode hydrolysis in OXG-RCBH.

	~~{{STRUCTURE_2ebs\| PDB=2ebs \| SCENE= }}~~		The structural basis for the exo-mode of action in GH74 oligoxyloglucan reducing end-specific cellobiohydrolase.,Yaoi K, Kondo H, Hiyoshi A, Noro N, Sugimoto H, Tsuda S, Mitsuishi Y, Miyazaki K J Mol Biol. 2007 Jun 29;370(1):53-62. Epub 2007 Apr 19. PMID:17498741<ref>PMID:17498741</ref>

	~~===Crystal Structure Anaalysis~~ of ~~Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17498741}}~~

	~~==About this Structure==~~
	~~[[2ebs]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Geotrichum_sp~~.~~_m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2EBS OCA].~~

	==See Also==		==See Also==
	*[[Cellobiohydrolase\|Cellobiohydrolase]]		*[[Cellobiohydrolase\|Cellobiohydrolase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:017498741<~~/~~ref~~><~~ref group="xtra">PMID:015242597</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Geotrichum sp. m128]]		[[Category: Geotrichum sp. m128]]
	[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]		[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]

OCA at 13:41, 20 October 2012

2012-10-20T13:41:10Z

← Older revision		Revision as of 13:41, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2ebs]] is a 2 chain structure ~~of [[Cellobiohydrolase]]~~ with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA].		[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA].

	==See Also==		==See Also==

OCA at 12:46, 26 July 2012

2012-07-26T12:46:06Z

← Older revision		Revision as of 12:46, 26 July 2012
Line 1:		Line 1:
	[[Image:2ebs.png\|left\|200px]]		[[Image:2ebs.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2ebs", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2ebs\| PDB=2ebs \| SCENE= }}		{{STRUCTURE_2ebs\| PDB=2ebs \| SCENE= }}

	===Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide===		===Crystal Structure Anaalysis of Oligoxyloglucan reducing-end-specific cellobiohydrolase (OXG-RCBH) D465N Mutant Complexed with a Xyloglucan Heptasaccharide===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17498741}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17498741 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_17498741}}		{{ABSTRACT_PUBMED_17498741}}

	==About this Structure==		==About this Structure==
	[[2ebs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA].		[[2ebs]] is a 2 chain structure of [[Cellobiohydrolase]] with sequence from [http://en.wikipedia.org/wiki/Geotrichum_sp._m128 Geotrichum sp. m128]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBS OCA].

			==See Also==
			*[[Cellobiohydrolase\|Cellobiohydrolase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17498741~~</ref><ref group="xtra">PMID:~~15242597~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017498741</ref><ref group="xtra">PMID:015242597</ref><references group="xtra"/>
	[[Category: Geotrichum sp. m128]]		[[Category: Geotrichum sp. m128]]
	[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]		[[Category: Oligoxyloglucan reducing-end-specific cellobiohydrolase]]