2ei4 - Revision history

OCA at 09:05, 6 November 2024

2024-11-06T09:05:43Z

← Older revision		Revision as of 09:05, 6 November 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei4_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 08:40, 25 October 2023

2023-10-25T08:40:53Z

← Older revision		Revision as of 08:40, 25 October 2023
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	<StructureSection load='2ei4' size='340' side='right'caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2ei4' size='340' side='right'caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_sp.~~_aus~~-2 Halobacterium sp. ~~aus~~-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_sp._AUS-2 Halobacterium sp. AUS-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vgo\|1vgo]], [[1uaz\|1uaz]]</div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [https://pdbe.org/2ei4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ei4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [https://pdbe.org/2ei4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ei4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei4 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/BACR2_HALS2 BACR2_HALS2]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Halobacterium sp. ~~aus~~-2]]		[[Category: Halobacterium sp. AUS-2]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kouyama, T]]		[[Category: Kouyama T]]
	~~[[Category: Bacterioruberin]]~~
	~~[[Category: Membrane protein]]~~
	~~[[Category: Proton pump]]~~
	~~[[Category: Retinal]]~~
	~~[[Category: Structural genomic]]~~
	~~[[Category: Transport protein~~]]

OCA at 17:24, 15 December 2021

2021-12-15T17:24:31Z

← Older revision		Revision as of 17:24, 15 December 2021
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	<StructureSection load='2ei4' size='340' side='right'caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2ei4' size='340' side='right'caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Halobacterium_sp._aus-2 Halobacterium sp. aus-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_sp._aus-2 Halobacterium sp. aus-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vgo\|1vgo]], [[1uaz\|1uaz]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [~~http~~://pdbe.org/2ei4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ei4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [https://pdbe.org/2ei4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ei4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:33, 11 March 2020

2020-03-11T08:33:04Z

← Older revision		Revision as of 08:33, 11 March 2020
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	==Trimeric complex of archaerhodopsin-2==		==Trimeric complex of archaerhodopsin-2==
	<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2ei4' size='340' side='right'caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._aus-2 Halobacterium sp. aus-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._aus-2 Halobacterium sp. aus-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin 3D structures\|Bacteriorhodopsin 3D structures]]
			*[[Rhodopsin 3D structures\|Rhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Halobacterium sp. aus-2]]		[[Category: Halobacterium sp. aus-2]]
			[[Category: Large Structures]]
	[[Category: Kouyama, T]]		[[Category: Kouyama, T]]
	[[Category: Bacterioruberin]]		[[Category: Bacterioruberin]]

OCA at 06:59, 6 June 2018

2018-06-06T06:59:10Z

← Older revision		Revision as of 06:59, 6 June 2018
Line 1:		Line 1:

	==Trimeric complex of archaerhodopsin-2==		==Trimeric complex of archaerhodopsin-2==
	<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Hals2 Hals2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._aus-2 Halobacterium sp. aus-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://pdbe.org/2ei4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://pdbe.org/2ei4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ei4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei4_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin\|Bacteriorhodopsin]]
	*[[Rhodopsin\|Rhodopsin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Hals2~~]]		[[Category: Halobacterium sp. aus-2]]
	[[Category: Kouyama, T]]		[[Category: Kouyama, T]]
	[[Category: Bacterioruberin]]		[[Category: Bacterioruberin]]
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	[[Category: Proton pump]]		[[Category: Proton pump]]
	[[Category: Retinal]]		[[Category: Retinal]]
			[[Category: Structural genomic]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 01:23, 9 February 2016

2016-02-09T01:23:46Z

← Older revision		Revision as of 01:23, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ei4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:15, 10 September 2015

2015-09-10T17:15:07Z

← Older revision		Revision as of 17:15, 10 September 2015
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	<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Archaea Archaea~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hals2 Hals2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://pdbe.org/2ei4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ei4" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Archaea~~]]		[[Category: Hals2]]
	[[Category: Kouyama, T]]		[[Category: Kouyama, T]]
	[[Category: Bacterioruberin]]		[[Category: Bacterioruberin]]

OCA at 03:28, 25 December 2014

2014-12-25T03:28:26Z

← Older revision		Revision as of 03:28, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaea Archaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaea Archaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Kouyama, T.]]		[[Category: Kouyama, T]]
	[[Category: Bacterioruberin]]		[[Category: Bacterioruberin]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 03:05, 29 September 2014

2014-09-29T03:05:16Z

← Older revision		Revision as of 03:05, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2ei4~~.~~png~~\|~~left~~\|~~200px~~]]		==Trimeric complex of archaerhodopsin-2==
			<StructureSection load='2ei4' size='340' side='right' caption='[[2ei4]], [[Resolution\|resolution]] 2.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaea Archaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EI4 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=22B:BACTERIORUBERIN'>22B</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=L2P:2,3-DI-PHYTANYL-GLYCEROL'>L2P</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vgo\|1vgo]], [[1uaz\|1uaz]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ei4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ei4 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2ei4_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Archaerhodopsin-2 (aR2), a retinal protein-carotenoid complex found in the claret membrane of Halorubrum sp. aus-2, functions as a light-driven proton pump. In this study, the membrane fusion method was utilized to prepare trigonal P321 crystals (a=b=98.2 A, c=56.2 A) and hexagonal P6(3) crystals (a=b=108.8 A, c=220.7 A). The trigonal crystal is made up of stacked membranes in which the aR2 trimers are arranged on a honeycomb lattice. Similar membranous structures are found in the hexagonal crystal, but four membrane layers with different orientations are contained in the unit cell. In these crystals, the carotenoid bacterioruberin [5,32-bis(2-hydroxypropan-2-yl)-2,8,12,16,21,25,29,35-octamethylhexatriaco nta-6,8,10,12,14,16,18,20,22,24,26,28,30-tridecaene-2,35-diol] binds to crevices between the subunits of the trimer. Its polyene chain is inclined from the membrane normal by an angle of about 20 degrees and, on the cytoplasmic side, it is surrounded by helices AB and DE of neighbouring subunits. This peculiar binding mode suggests that bacterioruberin plays a striking structural role for the trimerization of aR2. When compared with the aR2 structure in another crystal form containing no bacterioruberin, the proton release channel takes a more closed conformation in the P321 or P6(3) crystal; i.e., the native conformation of protein is stabilized in the trimeric protein-bacterioruberin complex. Interestingly, most residues participating in the trimerization are not conserved in bacteriorhodopsin, a homologous protein capable of forming a trimeric structure in the absence of bacterioruberin. Despite a large alteration in the amino acid sequence, the shape of the intratrimer hydrophobic space filled by lipids is highly conserved between aR2 and bacteriorhodopsin. Since a transmembrane helix facing this space undergoes a large conformational change during the proton pumping cycle, it is feasible that trimerization is an important strategy to capture special lipid components that are relevant to the protein activity.

	~~{{STRUCTURE_2ei4\| PDB=2ei4 \| SCENE= }}~~		Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-2.,Yoshimura K, Kouyama T J Mol Biol. 2008 Feb 1;375(5):1267-81. Epub 2007 Nov 22. PMID:18082767<ref>PMID:18082767</ref>

	~~===Trimeric complex~~ of ~~archaerhodopsin-2===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18082767}}~~

	~~==About this Structure==~~
	~~[[2ei4]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Archaea Archaea]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2EI4 OCA].~~

	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin\|Bacteriorhodopsin]]
	*[[Rhodopsin\|Rhodopsin]]		*[[Rhodopsin\|Rhodopsin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018082767<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Kouyama, T.]]		[[Category: Kouyama, T.]]

OCA at 12:09, 20 October 2012

2012-10-20T12:09:26Z

← Older revision		Revision as of 12:09, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2ei4]] is a 1 chain structure ~~of [[Bacteriorhodopsin]] and [[Rhodopsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Archaea Archaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA].		[[2ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaea Archaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EI4 OCA].

	==See Also==		==See Also==