2fba - Revision history

OCA at 09:24, 30 August 2023

2023-08-30T09:24:26Z

← Older revision		Revision as of 09:24, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2fba' size='340' side='right'caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='2fba' size='340' side='right'caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_36309 Atcc 36309~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE~~-1,~~3-DIOL'>TRS</scene></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.1Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em~~;~~'>[[1ayx\|1ayx]]</div>~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>GLU1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ATCC 36309])</td></tr>~~
	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Glucan_1,4~~-~~alpha~~-~~glucosidase Glucan 1,4~~-~~alpha~~-~~glucosidase], with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.2.~~1.3 ~~3.2.1.3]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [https://pdbe.org/2fba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [https://www.ebi.ac.uk/pdbsum/2fba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fba ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [https://pdbe.org/2fba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [https://www.ebi.ac.uk/pdbsum/2fba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fba ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/AMYG_SACFI AMYG_SACFI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 36309]]~~
	~~[[Category: Glucan 1,4-alpha-glucosidase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Dauter, Z]]		[[Category: Saccharomycopsis fibuligera]]
	[[Category: Gasperik, J]]		[[Category: Dauter Z]]
	[[Category: Hostinova, E]]		[[Category: Gasperik J]]
	[[Category: Sevcik, J]]		[[Category: Hostinova E]]
	[[Category: Solovicova, A]]		[[Category: Sevcik J]]
	[[Category: Wilson~~, K S]]~~		[[Category: Solovicova A]]
	~~[[Category: Hydrolase]]~~		[[Category: Wilson KS]]
	~~[[Category: Tri~~]]

OCA at 07:14, 24 February 2021

2021-02-24T07:14:24Z

← Older revision		Revision as of 07:14, 24 February 2021
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	==Glucoamylase from Saccharomycopsis fibuligera at atomic resolution==		==Glucoamylase from Saccharomycopsis fibuligera at atomic resolution==
	<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='2fba' size='340' side='right'caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_36309 Atcc 36309]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FBA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_36309 Atcc 36309]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ayx\|1ayx]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ATCC 36309])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ATCC 36309])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [~~http~~://pdbe.org/2fba PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fba PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fba ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [https://pdbe.org/2fba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [https://www.ebi.ac.uk/pdbsum/2fba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fba ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:

	==See Also==		==See Also==
	*[[Alpha-glucosidase\|Alpha-glucosidase]]		*[[Alpha-glucosidase 3D structures\|Alpha-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	[[Category: Atcc 36309]]		[[Category: Atcc 36309]]
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
			[[Category: Large Structures]]
	[[Category: Dauter, Z]]		[[Category: Dauter, Z]]
	[[Category: Gasperik, J]]		[[Category: Gasperik, J]]

OCA at 09:02, 14 June 2018

2018-06-14T09:02:53Z

← Older revision		Revision as of 09:02, 14 June 2018
Line 1:		Line 1:

	==Glucoamylase from Saccharomycopsis fibuligera at atomic resolution==		==Glucoamylase from Saccharomycopsis fibuligera at atomic resolution==
	<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Botryoascus_cladosporoides Botryoascus cladosporoides~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_36309 Atcc 36309]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ~~Botryoascus cladosporoides~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ATCC 36309])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://pdbe.org/2fba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://pdbe.org/2fba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fba ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fba_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fba_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2fba" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2fba" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Alpha-glucosidase\|Alpha-glucosidase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Botryoascus cladosporoides~~]]		[[Category: Atcc 36309]]
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	[[Category: Dauter, Z]]		[[Category: Dauter, Z]]

OCA at 13:21, 7 February 2016

2016-02-07T13:21:02Z

← Older revision		Revision as of 13:21, 7 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fba ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:50, 10 September 2015

2015-09-10T01:50:53Z

← Older revision		Revision as of 01:50, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>		<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomycopsis_fibuligera Saccharomycopsis fibuligera~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Botryoascus_cladosporoides Botryoascus cladosporoides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 ~~Saccharomycopsis fibuligera~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 Botryoascus cladosporoides])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://pdbe.org/2fba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2fba" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Botryoascus cladosporoides]]
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	~~[[Category: Saccharomycopsis fibuligera]]~~
	[[Category: Dauter, Z]]		[[Category: Dauter, Z]]
	[[Category: Gasperik, J]]		[[Category: Gasperik, J]]

OCA at 09:14, 16 January 2015

2015-01-16T09:14:16Z

← Older revision		Revision as of 09:14, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 Saccharomycopsis fibuligera])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 Saccharomycopsis fibuligera])</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	[[Category: Saccharomycopsis fibuligera]]		[[Category: Saccharomycopsis fibuligera]]
	[[Category: Dauter, Z.]]		[[Category: Dauter, Z]]
	[[Category: Gasperik, J.]]		[[Category: Gasperik, J]]
	[[Category: Hostinova, E.]]		[[Category: Hostinova, E]]
	[[Category: Sevcik, J.]]		[[Category: Sevcik, J]]
	[[Category: Solovicova, A.]]		[[Category: Solovicova, A]]
	[[Category: Wilson, K S.]]		[[Category: Wilson, K S]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Tri]]		[[Category: Tri]]

OCA at 01:09, 30 September 2014

2014-09-30T01:09:24Z

← Older revision		Revision as of 01:09, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2fba~~.~~png~~\|~~left~~\|~~200px~~]]		==Glucoamylase from Saccharomycopsis fibuligera at atomic resolution==
			<StructureSection load='2fba' size='340' side='right' caption='[[2fba]], [[Resolution\|resolution]] 1.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBA FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ayx\|1ayx]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">GLU1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4944 Saccharomycopsis fibuligera])</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,4-alpha-glucosidase Glucan 1,4-alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.3 3.2.1.3] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fba RCSB], [http://www.ebi.ac.uk/pdbsum/2fba PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fba_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Most glucoamylases (alpha-1,4-D-glucan glucohydrolase, EC 3.2.1.3) have structures consisting of both a catalytic and a starch binding domain. The structure of a glucoamylase from Saccharomycopsis fibuligera HUT 7212 (Glu), determined a few years ago, consists of a single catalytic domain. The structure of this enzyme with the resolution extended to 1.1 A and that of the enzyme-acarbose complex at 1.6 A resolution are presented here. The structure at atomic resolution, besides its high accuracy, shows clearly the influence of cryo-cooling, which is manifested in shrinkage of the molecule and lowering the volume of the unit cell. In the structure of the complex, two acarbose molecules are bound, one at the active site and the second at a site remote from the active site, curved around Tyr464 which resembles the inhibitor molecule in the 'sugar tongs' surface binding site in the structure of barley alpha-amylase isozyme 1 complexed with a thiomalto-oligosaccharide. Based on the close similarity in sequence of glucoamylase Glu, which does not degrade raw starch, to that of glucoamylase (Glm) from S. fibuligera IFO 0111, a raw starch-degrading enzyme, it is reasonable to expect the presence of the remote starch binding site at structurally equivalent positions in both enzymes. We propose the role of this site is to fix the enzyme onto the surface of a starch granule while the active site degrades the polysaccharide. This hypothesis is verified here by the preparation of mutants of glucoamylases Glu and Glm.

	~~{{STRUCTURE_2fba\| PDB=2fba \| SCENE= }}~~		Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain.,Sevcik J, Hostinova E, Solovicova A, Gasperik J, Dauter Z, Wilson KS FEBS J. 2006 May;273(10):2161-71. PMID:16649993<ref>PMID:16649993</ref>

	~~===Glucoamylase from Saccharomycopsis fibuligera at atomic resolution===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_16649993}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2fba]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:016649993<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	[[Category: Saccharomycopsis fibuligera]]		[[Category: Saccharomycopsis fibuligera]]

OCA: Protected "2fba" [edit=sysop:move=sysop]

2013-01-07T13:47:12Z

Protected "2fba" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:47, 7 January 2013
(No difference)

OCA at 13:47, 7 January 2013

2013-01-07T13:47:10Z

← Older revision		Revision as of 13:47, 7 January 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2fba.png\|left\|200px]]		[[Image:2fba.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2fba", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2fba\| PDB=2fba \| SCENE= }}		{{STRUCTURE_2fba\| PDB=2fba \| SCENE= }}

	===Glucoamylase from Saccharomycopsis fibuligera at atomic resolution===		===Glucoamylase from Saccharomycopsis fibuligera at atomic resolution===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16649993}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16649993 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_16649993}}		{{ABSTRACT_PUBMED_16649993}}

	==About this Structure==		==About this Structure==
	~~2FBA~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA].		[[2fba]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16649993~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016649993</ref><references group="xtra"/>
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	[[Category: Saccharomycopsis fibuligera]]		[[Category: Saccharomycopsis fibuligera]]
Line 32:		Line 20:
	[[Category: Solovicova, A.]]		[[Category: Solovicova, A.]]
	[[Category: Wilson, K S.]]		[[Category: Wilson, K S.]]
			[[Category: Hydrolase]]
	[[Category: Tri]]		[[Category: Tri]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:04:44 2009''~~

OCA at 12:04, 16 February 2009

2009-02-16T12:04:46Z

← Older revision		Revision as of 12:04, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
	2FBA is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA].		2FBA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomycopsis_fibuligera Saccharomycopsis fibuligera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBA OCA].

	==Reference==		==Reference==
	Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain., Sevcik J, Hostinova E, Solovicova A, Gasperik J, Dauter Z, Wilson KS, FEBS J. 2006 May;273(10):2161-71. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16649993 16649993]~~		<ref group="xtra">PMID:16649993</ref><references group="xtra"/>
	[[Category: Glucan 1,4-alpha-glucosidase]]		[[Category: Glucan 1,4-alpha-glucosidase]]
	[[Category: Saccharomycopsis fibuligera]]		[[Category: Saccharomycopsis fibuligera]]
	~~[[Category: Single protein]]~~
	[[Category: Dauter, Z.]]		[[Category: Dauter, Z.]]
	[[Category: Gasperik, J.]]		[[Category: Gasperik, J.]]
Line 35:		Line 34:
	[[Category: Tri]]		[[Category: Tri]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27~~ 16:37:~~56 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:04:44 2009''