2fbe - Revision history

OCA at 09:06, 6 November 2024

2024-11-06T09:06:37Z

← Older revision		Revision as of 09:06, 6 November 2024
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	<StructureSection load='2fbe' size='340' side='right'caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='2fbe' size='340' side='right'caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBE FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=MSE:SELENOMETHIONINE'>MSE</scene~~></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.52Å</td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~gene 19q13.4.1 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [https://pdbe.org/2fbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [https://www.ebi.ac.uk/pdbsum/2fbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [https://pdbe.org/2fbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [https://www.ebi.ac.uk/pdbsum/2fbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbe ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/RFPLA_HUMAN RFPLA_HUMAN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbe_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Briand, C]]		[[Category: Briand C]]
	[[Category: Capitani, G]]		[[Category: Capitani G]]
	[[Category: Gruetter, C]]		[[Category: Gruetter C]]
	[[Category: Gruetter~~, M G~~]]		[[Category: Gruetter MG]]
	[[Category: Mittl~~, P R]]~~		[[Category: Mittl PR]]
	~~[[Category: Dimer]]~~
	~~[[Category: Jellyroll beta-sandwich fold]]~~
	~~[[Category: Unknown function~~]]

OCA at 07:14, 24 February 2021

2021-02-24T07:14:27Z

← Older revision		Revision as of 07:14, 24 February 2021
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	==Crystal Structure of the PRYSPRY-domain==		==Crystal Structure of the PRYSPRY-domain==
	<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='2fbe' size='340' side='right'caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FBE FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [~~http~~://pdbe.org/2fbe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fbe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [https://pdbe.org/2fbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [https://www.ebi.ac.uk/pdbsum/2fbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</div>		</div>
	<div class="pdbe-citations 2fbe" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2fbe" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[User:Emi Nakayama/TRIM5a Homology Models\|User:Emi Nakayama/TRIM5a Homology Models]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Briand, C]]		[[Category: Briand, C]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]

OCA at 08:48, 14 June 2018

2018-06-14T08:48:10Z

← Older revision		Revision as of 08:48, 14 June 2018
Line 1:		Line 1:

	==Crystal Structure of the PRYSPRY-domain==		==Crystal Structure of the PRYSPRY-domain==
	<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>
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	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://pdbe.org/2fbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://pdbe.org/2fbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fbe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbe_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:43, 9 February 2016

2016-02-09T02:43:26Z

← Older revision		Revision as of 02:43, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fbe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:50, 10 September 2015

2015-09-10T17:50:10Z

← Older revision		Revision as of 17:50, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>		<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBE FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://pdbe.org/2fbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2fbe" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Briand, C]]		[[Category: Briand, C]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]

OCA at 03:51, 25 December 2014

2014-12-25T03:51:54Z

← Older revision		Revision as of 03:51, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBE FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Briand, C.]]		[[Category: Briand, C]]
	[[Category: Capitani, G.]]		[[Category: Capitani, G]]
	[[Category: Gruetter, C.]]		[[Category: Gruetter, C]]
	[[Category: Gruetter, M G.]]		[[Category: Gruetter, M G]]
	[[Category: Mittl, P R.]]		[[Category: Mittl, P R]]
	[[Category: Dimer]]		[[Category: Dimer]]
	[[Category: Jellyroll beta-sandwich fold]]		[[Category: Jellyroll beta-sandwich fold]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 01:47, 30 September 2014

2014-09-30T01:47:48Z

← Older revision		Revision as of 01:47, 30 September 2014
Line 1:		Line 1:
	~~{{STRUCTURE_2fbe~~\| ~~PDB~~=2fbe \| ~~SCENE~~= }}		==Crystal Structure of the PRYSPRY-domain==
	===~~Crystal Structure~~ of the ~~PRYSPRY~~-~~domain~~===		<StructureSection load='2fbe' size='340' side='right' caption='[[2fbe]], [[Resolution\|resolution]] 2.52Å' scene=''>
	~~{{ABSTRACT_PUBMED_16364311}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FBE FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gene 19q13.4.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fbe RCSB], [http://www.ebi.ac.uk/pdbsum/2fbe PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/2fbe_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			We determined the first structure of PRYSPRY, a domain found in over 500 different proteins, involved in innate immune signaling, cytokine signaling suppression, development, cell growth and retroviral restriction. The fold encompasses a 7-stranded and a 6-stranded antiparallel beta-sheet, arranged in a beta-sandwich. In the crystal, PRYSPRY forms a dimer where the C-terminus of an acceptor molecule binds to the concave surface of a donor molecule, which represents a putative interaction site. Mutations in the PRYSPRY domains of Pyrin, which are responsible for familial Mediterranean fever, map on the putative PRYSPRY interaction site.

	~~==About this~~ Structure==		Structure of the PRYSPRY-domain: implications for autoinflammatory diseases.,Grutter C, Briand C, Capitani G, Mittl PR, Papin S, Tschopp J, Grutter MG FEBS Lett. 2006 Jan 9;580(1):99-106. Epub 2005 Dec 9. PMID:16364311<ref>PMID:16364311</ref>
	~~[[2fbe]] is a 4 chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.~~il/oca-bin~~/~~ocashort?id=2FBE OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[User:Emi Nakayama/TRIM5a Homology Models\|User:Emi Nakayama/TRIM5a Homology Models]]		*[[User:Emi Nakayama/TRIM5a Homology Models\|User:Emi Nakayama/TRIM5a Homology Models]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:016364311<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Briand, C.]]		[[Category: Briand, C.]]

OCA at 10:23, 11 March 2013

2013-03-11T10:23:47Z

← Older revision		Revision as of 10:23, 11 March 2013
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	~~[[Image:2fbe.png\|left\|200px]]~~

	{{STRUCTURE_2fbe\| PDB=2fbe \| SCENE= }}		{{STRUCTURE_2fbe\| PDB=2fbe \| SCENE= }}

	===Crystal Structure of the PRYSPRY-domain===		===Crystal Structure of the PRYSPRY-domain===

	{{ABSTRACT_PUBMED_16364311}}		{{ABSTRACT_PUBMED_16364311}}

OCA: Protected "2fbe" [edit=sysop:move=sysop]

2013-01-07T11:43:24Z

Protected "2fbe" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:43, 7 January 2013
(No difference)

OCA at 11:43, 7 January 2013

2013-01-07T11:43:22Z

← Older revision		Revision as of 11:43, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2fbe.png\|left\|200px]]		[[Image:2fbe.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2fbe", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2fbe\| PDB=2fbe \| SCENE= }}		{{STRUCTURE_2fbe\| PDB=2fbe \| SCENE= }}

	===Crystal Structure of the PRYSPRY-domain===		===Crystal Structure of the PRYSPRY-domain===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_16364311}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 16364311 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_16364311}}		{{ABSTRACT_PUBMED_16364311}}

	==About this Structure==		==About this Structure==
	~~2FBE~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA].		[[2fbe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FBE OCA].

			==See Also==
			*[[User:Emi Nakayama/TRIM5a Homology Models\|User:Emi Nakayama/TRIM5a Homology Models]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~16364311~~</ref><references group="xtra"/>		<ref group="xtra">PMID:016364311</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Briand, C.]]		[[Category: Briand, C.]]
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	[[Category: Dimer]]		[[Category: Dimer]]
	[[Category: Jellyroll beta-sandwich fold]]		[[Category: Jellyroll beta-sandwich fold]]
			[[Category: Unknown function]]
	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 05:49:24 2009''~~