2fvb - Revision history

OCA at 14:37, 29 December 2021

2021-12-29T14:37:38Z

← Older revision		Revision as of 14:37, 29 December 2021
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	<StructureSection load='2fvb' size='340' side='right'caption='[[2fvb]]' scene=''>		<StructureSection load='2fvb' size='340' side='right'caption='[[2fvb]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FVB FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FVB FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=2fvb FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/2fvb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvb ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fvb FirstGlance], [https://www.ebi.ac.uk/pdbsum/2fvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:06, 27 March 2020

2020-03-27T11:06:01Z

← Older revision		Revision as of 11:06, 27 March 2020
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	==MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN==		==MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN==
	<StructureSection load='2fvb' size='340' side='right' caption='[[2fvb]]' scene=''>		<StructureSection load='2fvb' size='340' side='right'caption='[[2fvb]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
			[[Category: Large Structures]]
	[[Category: Kabat, E A]]		[[Category: Kabat, E A]]
	[[Category: Padlan, E A]]		[[Category: Padlan, E A]]

OCA at 06:58, 20 June 2018

2018-06-20T06:58:19Z

← Older revision		Revision as of 06:58, 20 June 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fvb FirstGlance], [http://www.ebi.ac.uk/pdbsum/2fvb PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fvb FirstGlance], [http://www.ebi.ac.uk/pdbsum/2fvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:37, 11 February 2016

2016-02-11T10:37:17Z

← Older revision		Revision as of 10:37, 11 February 2016
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			{{Theoretical_model}}

	==MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN==		==MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN==
	<StructureSection load='2fvb' size='340' side='right' caption='[[2fvb]]' scene=''>		<StructureSection load='2fvb' size='340' side='right' caption='[[2fvb]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Theoretical Model]]
	[[Category: Kabat, E A]]		[[Category: Kabat, E A]]
	[[Category: Padlan, E A]]		[[Category: Padlan, E A]]

OCA at 06:16, 10 September 2015

2015-09-10T06:16:24Z

← Older revision		Revision as of 06:16, 10 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2fvb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:02, 16 January 2015

2015-01-16T09:02:32Z

← Older revision		Revision as of 09:02, 16 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fvb FirstGlance], [http://www.ebi.ac.uk/pdbsum/2fvb PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fvb FirstGlance], [http://www.ebi.ac.uk/pdbsum/2fvb PDBsum]</span></td></tr>
	<table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 04:00, 29 September 2014

2014-09-29T04:00:34Z

← Older revision		Revision as of 04:00, 29 September 2014
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	~~{{Theoretical_model}}~~		==MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN==
			<StructureSection load='2fvb' size='340' side='right' caption='[[2fvb]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FVB FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fvb FirstGlance], [http://www.ebi.ac.uk/pdbsum/2fvb PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Models of the Fv portion (containing the variable regions of the heavy and light chains) of two monoclonal anti-alpha (1----6)dextran antibodies, W3129 and 19.1.2, were constructed from amino acid sequences and the known three-dimensional structures of the Fv portions of McPC603 and J539. The modeled combining site of W3129 has a protrusion on one side, formed by the long complementarity-determining region 1 of the light chain and the long complementarity-determining region 3 of the heavy chain, and has a cavity accommodating a glucose moiety. The model of the 19.1.2 site is basically flat with a shallow groove that can accommodate several internal glucose units. These results support the earlier conclusions, from ligand binding data, that W3129 has a cavity-type site, involving the terminal nonreducing glucose residue (endbinder), whereas 19.1.2 has a groove-type site.

	~~[[Image~~:~~2fvb~~.~~png\|left\|200px]]~~		Model-building study of the combining sites of two antibodies to alpha (1----6)dextran.,Padlan EA, Kabat EA Proc Natl Acad Sci U S A. 1988 Sep;85(18):6885-9. PMID:2457920<ref>PMID:2457920</ref>

	~~{{STRUCTURE_2fvb\| PDB=2fvb \| SCENE= }}~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~===MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN===~~		== References ==
			<references/>
	~~{{ABSTRACT_PUBMED_2457920}}~~		__TOC__
			</StructureSection>
	==~~Reference~~==
	<~~ref group="xtra">PMID:002457920<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Kabat, E A]]		[[Category: Kabat, E A]]
	[[Category: Padlan, E A]]		[[Category: Padlan, E A]]

OCA: Protected "2fvb" [edit=sysop:move=sysop]

2012-10-21T09:38:15Z

Protected "2fvb" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:38, 21 October 2012
(No difference)

OCA at 09:38, 21 October 2012

2012-10-21T09:38:10Z

← Older revision		Revision as of 09:38, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
	~~{{Seed}}~~
	[[Image:2fvb.png\|left\|200px]]		[[Image:2fvb.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2fvb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2fvb\| PDB=2fvb \| SCENE= }}		{{STRUCTURE_2fvb\| PDB=2fvb \| SCENE= }}

	===MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN===		===MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_2457920}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 2457920 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_2457920}}		{{ABSTRACT_PUBMED_2457920}}

	~~==About this Structure==~~
	~~Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVB OCA].~~

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~2457920~~</ref><references group="xtra"/>		<ref group="xtra">PMID:002457920</ref><references group="xtra"/>
	[[Category: Kabat, E A]]		[[Category: Kabat, E A]]
	[[Category: Padlan, E A]]		[[Category: Padlan, E A]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:41:59 2010''~~

OCA at 05:41, 8 April 2010

2010-04-08T05:41:59Z

@@ Line 1: / Line 1: @@
-'''Theoretical Model'''
+{{Theoretical_model}}
-The entry 2FVB is a Theoretical Model titled 'MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN'.
+<!--
-[[Category:Theoretical Model]]
+===MODEL-BUILDING STUDY OF THE COMBINING SITES OF TWO ANTIBODIES TO ALPHA(1(RIGHT ARROW)6)DEXTRAN===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 30 09:56:41 2008''
+<!--