2gap - Revision history

OCA at 14:42, 29 December 2021

2021-12-29T14:42:35Z

← Older revision		Revision as of 14:42, 29 December 2021
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	<StructureSection load='2gap' size='340' side='right'caption='[[2gap]]' scene=''>		<StructureSection load='2gap' size='340' side='right'caption='[[2gap]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2GAP FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GAP FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=2gap FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/2gap PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2gap ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gap FirstGlance], [https://www.ebi.ac.uk/pdbsum/2gap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gap ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:12, 27 March 2020

2020-03-27T11:12:00Z

← Older revision		Revision as of 11:12, 27 March 2020
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	==MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY==		==MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY==
	<StructureSection load='2gap' size='340' side='right' caption='[[2gap]]' scene=''>		<StructureSection load='2gap' size='340' side='right'caption='[[2gap]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
			[[Category: Large Structures]]
	[[Category: Steitz, T A]]		[[Category: Steitz, T A]]
	[[Category: Weber, I T]]		[[Category: Weber, I T]]

OCA at 07:21, 20 June 2018

2018-06-20T07:21:35Z

← Older revision		Revision as of 07:21, 20 June 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gap FirstGlance], [http://www.ebi.ac.uk/pdbsum/2gap PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gap FirstGlance], [http://www.ebi.ac.uk/pdbsum/2gap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gap ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:39, 11 February 2016

2016-02-11T10:39:35Z

← Older revision		Revision as of 10:39, 11 February 2016
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			{{Theoretical_model}}

	==MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY==		==MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY==
	<StructureSection load='2gap' size='340' side='right' caption='[[2gap]]' scene=''>		<StructureSection load='2gap' size='340' side='right' caption='[[2gap]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Theoretical Model]]
	[[Category: Steitz, T A]]		[[Category: Steitz, T A]]
	[[Category: Weber, I T]]		[[Category: Weber, I T]]

OCA at 17:06, 11 September 2015

2015-09-11T17:06:47Z

← Older revision		Revision as of 17:06, 11 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2gap" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:37, 16 January 2015

2015-01-16T08:37:44Z

← Older revision		Revision as of 08:37, 16 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gap FirstGlance], [http://www.ebi.ac.uk/pdbsum/2gap PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gap FirstGlance], [http://www.ebi.ac.uk/pdbsum/2gap PDBsum]</span></td></tr>
	<table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 02:37, 29 September 2014

2014-09-29T02:37:18Z

← Older revision		Revision as of 02:37, 29 September 2014
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	~~{{Theoretical_model}}~~		==MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY==
			<StructureSection load='2gap' size='340' side='right' caption='[[2gap]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GAP FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gap FirstGlance], [http://www.ebi.ac.uk/pdbsum/2gap PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Calculation of the electrostatic potential energy surfaces of Escherichia coli catabolite gene activator protein (CAP) dimer suggests a model for the complex between CAP and a specific DNA sequence. The positive electrostatic charge density of CAP lies on the two COOH-terminal domains and about 20-30 A from the molecular 2-fold axis. Assuming that the 2-fold axes of the CAP dimer and the DNA to which it binds are coincident, the positions of the positive electrostatic potential surfaces strongly suggest the rotational orientation of the DNA relative to the protein. A specific complex between CAP and its DNA binding site in the lac operon has been built with the DNA in this orientation. The amino ends of the two protruding F alpha-helices interact in successive major grooves of the DNA. Four side chains emanating from each F helix can form hydrogen bonds with the exposed edges of four bases in the major groove. Electrostatic considerations as well as the necessity to make interactions between CAP and a DNA site as much as 20 base pairs long require us to bend or kink the DNA. In our model of CAP complexed with B-DNA, as with those proposed for Cro and lambda cI repressors, the protruding second helices of the two-helix motif from both subunits interact in successive major grooves of B-DNA. However, unlike Cro and similar to lambda cI, the protruding alpha-helices are nearly parallel to the bases rather than the groove.

	~~[[Image~~:~~2gap~~.~~png\|left\|200px]]~~		Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.,Weber IT, Steitz TA Proc Natl Acad Sci U S A. 1984 Jul;81(13):3973-7. PMID:6377305<ref>PMID:6377305</ref>

	~~{{STRUCTURE_2gap\| PDB=2gap \| SCENE= }}~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~===MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY===~~		== References ==
			<references/>
	~~{{ABSTRACT_PUBMED_6377305}}~~		__TOC__
			</StructureSection>
	==~~Reference~~==
	<~~ref group="xtra">PMID:006377305<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Steitz, T A]]		[[Category: Steitz, T A]]
	[[Category: Weber, I T]]		[[Category: Weber, I T]]

OCA: Protected "2gap" [edit=sysop:move=sysop]

2012-10-21T09:15:24Z

Protected "2gap" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:15, 21 October 2012
(No difference)

OCA at 09:15, 21 October 2012

2012-10-21T09:15:21Z

← Older revision		Revision as of 09:15, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
	~~{{Seed}}~~
	[[Image:2gap.png\|left\|200px]]		[[Image:2gap.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2gap", creates the "Structure Box" on the page.~~
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	{{STRUCTURE_2gap\| PDB=2gap \| SCENE= }}		{{STRUCTURE_2gap\| PDB=2gap \| SCENE= }}

	===MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY===		===MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_6377305}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_6377305}}		{{ABSTRACT_PUBMED_6377305}}

	~~==About this Structure==~~
	~~Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAP OCA].~~

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~6377305~~</ref><references group="xtra"/>		<ref group="xtra">PMID:006377305</ref><references group="xtra"/>
	[[Category: Steitz, T A]]		[[Category: Steitz, T A]]
	[[Category: Weber, I T]]		[[Category: Weber, I T]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 07:58:18 2010''~~

OCA at 04:58, 8 April 2010

2010-04-08T04:58:19Z

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-'''Theoretical Model'''
+{{Theoretical_model}}
-The entry 2GAP is a Theoretical Model titled 'MODEL OF SPECIFIC COMPLEX BETWEEN CATABOLITE GENE ACTIVATOR PROTEIN AND B-DNA SUGGESTED BY ELECTROSTATIC COMPLEMENTARITY'.
+<!--
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-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 30 09:56:50 2008''
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