2gl2 - Revision history

OCA at 13:06, 26 July 2023

2023-07-26T13:06:01Z

← Older revision		Revision as of 13:06, 26 July 2023
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	<StructureSection load='2gl2' size='340' side='right'caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2gl2' size='340' side='right'caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2avr\|2avr]]~~, [[~~2gkq~~\|~~2gkq~~]]~~, [[2gld\|2gld]]</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [https://pdbe.org/2gl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gl2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [https://pdbe.org/2gl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gl2 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q5I6B0_FUSNU Q5I6B0_FUSNU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus fusiformis veillon and zuber 1898~~]]		[[Category: Fusobacterium nucleatum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Han~~, Y W~~]]		[[Category: Han YW]]
	[[Category: Nithianantham, S]]		[[Category: Nithianantham S]]
	[[Category: Shoham, M]]		[[Category: Shoham M]]
	[[Category: Wu, N]]		[[Category: Wu N]]
	[[Category: Xu, M]]		[[Category: Xu M]]
	~~[[Category: Antiparallel helix-loop-helix]]~~
	~~[[Category: Cell adhesion]]~~
	~~[[Category: Fada gly4 mutant~~]]

OCA at 09:58, 5 May 2021

2021-05-05T09:58:33Z

← Older revision		Revision as of 09:58, 5 May 2021
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	<StructureSection load='2gl2' size='340' side='right'caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2gl2' size='340' side='right'caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [~~http~~://pdbe.org/2gl2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2gl2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2gl2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [https://pdbe.org/2gl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gl2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:56, 24 July 2019

2019-07-24T08:56:31Z

← Older revision		Revision as of 08:56, 24 July 2019
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	==Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA==		==Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA==
	<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2gl2' size='340' side='right'caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 2gl2" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2gl2" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus fusiformis veillon and zuber 1898]]		[[Category: Bacillus fusiformis veillon and zuber 1898]]
			[[Category: Large Structures]]
	[[Category: Han, Y W]]		[[Category: Han, Y W]]
	[[Category: Nithianantham, S]]		[[Category: Nithianantham, S]]

OCA at 07:55, 18 October 2017

2017-10-18T07:55:58Z

← Older revision		Revision as of 07:55, 18 October 2017
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	==Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA==		==Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA==
	<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
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	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://pdbe.org/2gl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://pdbe.org/2gl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gl2 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:36, 10 September 2015

2015-09-10T04:36:08Z

← Older revision		Revision as of 04:36, 10 September 2015
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	<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Fusobacterium_nucleatum Fusobacterium nucleatum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fusiformis"_veillon_and_zuber_1898 "bacillus fusiformis" veillon and zuber 1898]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://pdbe.org/2gl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2gl2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Fusobacterium nucleatum~~]]		[[Category: Bacillus fusiformis veillon and zuber 1898]]
	[[Category: Han, Y W]]		[[Category: Han, Y W]]
	[[Category: Nithianantham, S]]		[[Category: Nithianantham, S]]

OCA at 22:32, 3 January 2015

2015-01-03T22:32:58Z

← Older revision		Revision as of 22:32, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>
	<table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Fusobacterium nucleatum]]		[[Category: Fusobacterium nucleatum]]
	[[Category: Han, Y W.]]		[[Category: Han, Y W]]
	[[Category: Nithianantham, S.]]		[[Category: Nithianantham, S]]
	[[Category: Shoham, M.]]		[[Category: Shoham, M]]
	[[Category: Wu, N.]]		[[Category: Wu, N]]
	[[Category: Xu, M.]]		[[Category: Xu, M]]
	[[Category: Antiparallel helix-loop-helix]]		[[Category: Antiparallel helix-loop-helix]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Fada gly4 mutant]]		[[Category: Fada gly4 mutant]]

OCA at 06:47, 9 June 2014

2014-06-09T06:47:24Z

← Older revision		Revision as of 06:47, 9 June 2014
Line 1:		Line 1:
	[[~~Image~~:~~2gl2~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA==
			<StructureSection load='2gl2' size='340' side='right' caption='[[2gl2]], [[Resolution\|resolution]] 2.50Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GL2 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2avr\|2avr]], [[2gkq\|2gkq]], [[2gld\|2gld]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gl2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gl2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gl2 PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Fusobacterium nucleatum is a gram-negative anaerobe prevalent in the oral cavity that is associated with periodontal disease, preterm birth and infections in other parts of the human body. The bacteria attach to and invade epithelial and endothelial cells in the gum tissue and elsewhere via a 13.7 kDa adhesin protein FadA (Fusobacterium adhesin A). FadA exists in two forms: the intact form (pre-FadA), consisting of 129 amino acids, and the mature form (mFadA), which lacks an 18-residue signal sequence. Both forms have been expressed in Escherichia coli and purified. mFadA has been crystallized. The crystals belong to the hexagonal space group P6(1) or P6(5), with unit-cell parameters a = b = 59.3, c = 125.7 A and one molecule per asymmetric unit. The crystals exhibit an unusually high solvent content of 74%. Synchrotron X-ray data have been collected to 1.9 A. The crystals are suitable for X-ray structure determination. The crystal structure of FadA may provide a basis for the development of therapeutic agents to combat periodontal disease and other infections associated with F. nucleatum.

	~~{{STRUCTURE_2gl2\| PDB=2gl2 \| SCENE= }}~~		Crystallization and preliminary X-ray data of the FadA adhesin from Fusobacterium nucleatum.,Nithianantham S, Xu M, Wu N, Han YW, Shoham M Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1215-7. Epub 2006 Nov 4. PMID:17142900<ref>PMID:17142900</ref>

	~~===Crystal structure~~ of the ~~tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17142900}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2gl2]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:017142900<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Fusobacterium nucleatum]]		[[Category: Fusobacterium nucleatum]]
	[[Category: Han, Y W.]]		[[Category: Han, Y W.]]

OCA: Protected "2gl2" [edit=sysop:move=sysop]

2012-08-14T17:19:16Z

Protected "2gl2" [edit=sysop:move=sysop]

← Older revision	Revision as of 17:19, 14 August 2012
(No difference)

OCA at 17:19, 14 August 2012

2012-08-14T17:19:15Z

← Older revision		Revision as of 17:19, 14 August 2012
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	~~{{Seed}}~~
	[[Image:2gl2.png\|left\|200px]]		[[Image:2gl2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2gl2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2gl2\| PDB=2gl2 \| SCENE= }}		{{STRUCTURE_2gl2\| PDB=2gl2 \| SCENE= }}

	===Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA===		===Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17142900}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17142900 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_17142900}}		{{ABSTRACT_PUBMED_17142900}}

	==About this Structure==		==About this Structure==
	~~2GL2 is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA].		[[2gl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusobacterium_nucleatum Fusobacterium nucleatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GL2 OCA].

	==Reference==		==Reference==
	Crystallization and preliminary X-ray data of the FadA adhesin from Fusobacterium nucleatum., Nithianantham S, Xu M, Wu N, Han YW, Shoham M, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt, 12):1215-7. Epub 2006 Nov 4. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~17142900 17142900]~~		<ref group="xtra">PMID:017142900</ref><references group="xtra"/>
	[[Category: Fusobacterium nucleatum]]		[[Category: Fusobacterium nucleatum]]
	~~[[Category: Single protein]]~~
	[[Category: Han, Y W.]]		[[Category: Han, Y W.]]
	[[Category: Nithianantham, S.]]		[[Category: Nithianantham, S.]]
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	[[Category: Xu, M.]]		[[Category: Xu, M.]]
	[[Category: Antiparallel helix-loop-helix]]		[[Category: Antiparallel helix-loop-helix]]
			[[Category: Cell adhesion]]
	[[Category: Fada gly4 mutant]]		[[Category: Fada gly4 mutant]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:18:27 2008''~~

OCA at 16:18, 27 July 2008

2008-07-27T16:18:32Z

← Older revision		Revision as of 16:18, 27 July 2008
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			[[Image:2gl2.png\|left\|200px]]

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	{{STRUCTURE_2gl2\| PDB=2gl2 \| SCENE= }}		{{STRUCTURE_2gl2\| PDB=2gl2 \| SCENE= }}

	~~'''~~Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA~~'''~~		===Crystal structure of the tetra muntant (T66G,R67G,F68G,Y69G) of bacterial adhesin FadA===


	~~==Overview==~~		<!--
	~~Fusobacterium nucleatum is a gram-negative anaerobe prevalent in the oral cavity that is associated with periodontal disease~~, ~~preterm birth and infections in other parts of~~ the ~~human body. The bacteria attach~~ to ~~and invade epithelial and endothelial cells in~~ the ~~gum tissue and elsewhere via a 13.7 kDa adhesin protein FadA~~ (~~Fusobacterium adhesin A). FadA exists in two forms~~: ~~the intact form (pre-FadA), consisting of 129 amino acids, and the mature form (mFadA), which lacks an 18-residue signal sequence. Both forms have been expressed in Escherichia coli and purified~~. ~~mFadA has been crystallized~~. ~~The crystals belong to the hexagonal space group P6(1) or P6(5~~), ~~with unit-cell parameters a = b = 59~~.~~3, c = 125.7 A and one molecule per asymmetric unit. The crystals exhibit an unusually high solvent content of 74%. Synchrotron X~~-~~ray data have been collected to 1.9 A. The crystals are suitable for X~~-ray structure determination. The crystal structure of FadA may provide a basis for the development of therapeutic agents to combat periodontal disease and other infections associated with F. nucleatum.		The line below this paragraph, {{ABSTRACT_PUBMED_17142900}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 17142900 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_17142900}}

	==About this Structure==		==About this Structure==
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	[[Category: Antiparallel helix-loop-helix]]		[[Category: Antiparallel helix-loop-helix]]
	[[Category: Fada gly4 mutant]]		[[Category: Fada gly4 mutant]]
	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 05~~:13:27 2008''
			''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:18:27 2008''