2gvb - Revision history

OCA at 19:00, 29 May 2024

2024-05-29T19:00:33Z

← Older revision		Revision as of 19:00, 29 May 2024
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	==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==		==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
	<StructureSection load='2gvb' size='340' side='right'caption='[[2gvb~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>		<StructureSection load='2gvb' size='340' side='right'caption='[[2gvb]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_M13 Escherichia virus M13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[2gva\|2gva]]</div~~></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [https://pdbe.org/2gvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [https://www.ebi.ac.uk/pdbsum/2gvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [https://pdbe.org/2gvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [https://www.ebi.ac.uk/pdbsum/2gvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.		[https://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Escherichia virus M13]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Folkers~~, P J.M~~]]		[[Category: Folkers PJM]]
	[[Category: Folmer~~, R H.A~~]]		[[Category: Folmer RHA]]
	[[Category: Hilbers~~, C W~~]]		[[Category: Hilbers CW]]
	[[Category: Konings~~, R N.H~~]]		[[Category: Konings RNH]]
	[[Category: Nilges, M]]		[[Category: Nilges M]]
	[[Category: Prompers~~, J J~~]]		[[Category: Prompers JJ]]

OCA at 11:02, 5 January 2022

2022-01-05T11:02:24Z

← Older revision		Revision as of 11:02, 5 January 2022
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	<StructureSection load='2gvb' size='340' side='right'caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2gvb' size='340' side='right'caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gva\|2gva]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [~~http~~://pdbe.org/2gvb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2gvb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [https://pdbe.org/2gvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [https://www.ebi.ac.uk/pdbsum/2gvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.		[[https://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:02, 1 April 2020

2020-04-01T10:02:02Z

← Older revision		Revision as of 10:02, 1 April 2020
Line 1:		Line 1:

	==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==		==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
	<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2gvb' size='340' side='right'caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Single-stranded DNA-binding protein\|Single-stranded DNA-binding protein]]		*[[Single-stranded DNA-binding protein 3D structures\|Single-stranded DNA-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Folkers, P J.M]]		[[Category: Folkers, P J.M]]
	[[Category: Folmer, R H.A]]		[[Category: Folmer, R H.A]]

OCA at 06:41, 27 June 2018

2018-06-27T06:41:54Z

← Older revision		Revision as of 06:41, 27 June 2018
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	==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==		==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
	<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Bpm13 Bpm13]~~. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://pdbe.org/2gvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://pdbe.org/2gvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Bpm13]]~~
	[[Category: Folkers, P J.M]]		[[Category: Folkers, P J.M]]
	[[Category: Folmer, R H.A]]		[[Category: Folmer, R H.A]]

OCA at 22:12, 8 February 2016

2016-02-08T22:12:52Z

← Older revision		Revision as of 22:12, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gvb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:51, 10 September 2015

2015-09-10T15:51:28Z

← Older revision		Revision as of 15:51, 10 September 2015
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	<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_m13 Enterobacteria phage m13~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpm13 Bpm13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://pdbe.org/2gvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~VHED_BPM13 VHED_BPM13~~]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.		[[http://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2gvb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Enterobacteria phage m13~~]]		[[Category: Bpm13]]
	[[Category: Folkers, P J.M]]		[[Category: Folkers, P J.M]]
	[[Category: Folmer, R H.A]]		[[Category: Folmer, R H.A]]

OCA at 02:28, 25 December 2014

2014-12-25T02:28:54Z

← Older revision		Revision as of 02:28, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/VHED_BPM13 VHED_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Enterobacteria phage m13]]		[[Category: Enterobacteria phage m13]]
	[[Category: Folkers, P J.M.]]		[[Category: Folkers, P J.M]]
	[[Category: Folmer, R H.A.]]		[[Category: Folmer, R H.A]]
	[[Category: Hilbers, C W.]]		[[Category: Hilbers, C W]]
	[[Category: Konings, R N.H.]]		[[Category: Konings, R N.H]]
	[[Category: Nilges, M.]]		[[Category: Nilges, M]]
	[[Category: Prompers, J J.]]		[[Category: Prompers, J J]]

OCA at 10:45, 30 September 2014

2014-09-30T10:45:52Z

← Older revision		Revision as of 10:45, 30 September 2014
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	[[Image:~~2gvb~~.~~png~~\|~~left~~\|~~200px~~]]		==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
			<StructureSection load='2gvb' size='340' side='right' caption='[[2gvb]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVB FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2gva\|2gva]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gvb RCSB], [http://www.ebi.ac.uk/pdbsum/2gvb PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gvb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The three-dimensional solution structure of mutant Tyr41-->His of the single-stranded DNA binding protein encoded by gene V of the filamentous bacteriophage M13 has been refined in two stages. The first stage involved the collection of additional NOE-based distance constraints, which were then used in eight cycles of back-calculations and structure calculations. The structures of the gene V protein dimers were calculated using simulated annealing, employing restrained molecular dynamics with a geometric force field. In the second stage of the refinement procedure, solvent was explicitly included during the dynamic calculations. A total of 30 structures was calculated for the protein, representing its solution structure in water. The first calculation step significantly improved the convergence of the structures, whereas the subsequent simulations in water made the structures physically more realistic. This is, for instance, illustrated by the number of hydrogen bonds formed in the molecule, which increased considerably upon going to aqueous solution. It is shown that the solution structure of the mutant gene V protein is nearly identical to the crystal structure of the wild-type molecule, except for the DNA-binding loop (residues 16-28). This antiparallel beta-hairpin is twisted and partially folded back towards the core of the protein in the NMR structure, whereas it is more extended and points away from the rest of the molecule in the X-ray structure. Unrestrained molecular dynamics calculations suggest that this latter conformation is energetically unstable in solution.

	~~{{STRUCTURE_2gvb\| PDB=2gvb \| SCENE= }}~~		Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure.,Prompers JJ, Folmer RH, Nilges M, Folkers PJ, Konings RN, Hilbers CW Eur J Biochem. 1995 Sep 1;232(2):506-14. PMID:7556200<ref>PMID:7556200</ref>

	~~===REFINED SOLUTION STRUCTURE OF THE TYR 41--~~> ~~HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_7556200}}~~		==See Also==
			*[[Single-stranded DNA-binding protein\|Single-stranded DNA-binding protein]]
	==~~About this Structure~~==		== References ==
	[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-~~bin/send~~-~~pdb?obs=1&id=1gvb 1gvb~~]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA~~].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:007556200<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Enterobacteria phage m13]]		[[Category: Enterobacteria phage m13]]
	[[Category: Folkers, P J.M.]]		[[Category: Folkers, P J.M.]]

OCA: Protected "2gvb" [edit=sysop:move=sysop]

2013-01-07T15:14:53Z

Protected "2gvb" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:14, 7 January 2013
(No difference)

OCA at 15:14, 7 January 2013

2013-01-07T15:14:51Z

← Older revision		Revision as of 15:14, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2gvb.png\|left\|200px]]		[[Image:2gvb.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2gvb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2gvb\| PDB=2gvb \| SCENE= }}		{{STRUCTURE_2gvb\| PDB=2gvb \| SCENE= }}

	===REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE===		===REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_7556200}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_7556200}}		{{ABSTRACT_PUBMED_7556200}}

	==About this Structure==		==About this Structure==
	~~2GVB~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA].		[[2gvb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_m13 Enterobacteria phage m13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gvb 1gvb]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVB OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~7556200~~</ref><references group="xtra"/>		<ref group="xtra">PMID:007556200</ref><references group="xtra"/>
	[[Category: Enterobacteria phage m13]]		[[Category: Enterobacteria phage m13]]
	[[Category: Folkers, P J.M.]]		[[Category: Folkers, P J.M.]]
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	[[Category: Nilges, M.]]		[[Category: Nilges, M.]]
	[[Category: Prompers, J J.]]		[[Category: Prompers, J J.]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:54:52 2009''~~